Rudi Fasan
Rudi Fasan
Robert Welch Professor of Chemistry, Dept of Chemistry & Biochemistry, University of Texas at Dallas
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Zitiert von
Zitiert von
Tuning P450 enzymes as oxidation catalysts
R Fasan
Acs Catalysis 2 (4), 647-666, 2012
Engineered Alkane‐Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties
R Fasan, MM Chen, NC Crook, FH Arnold
Angewandte Chemie International Edition 46 (44), 8414-8418, 2007
Exploiting and engineering hemoproteins for abiological carbene and nitrene transfer reactions
OF Brandenberg, R Fasan, FH Arnold
Current opinion in biotechnology 47, 102-111, 2017
Highly diastereoselective and enantioselective olefin cyclopropanation using engineered myoglobin‐based catalysts
M Bordeaux, V Tyagi, R Fasan
Angewandte Chemie 127 (6), 1764-1768, 2015
Molecular basis of RNA recognition by the human alternative splicing factor Fox‐1
SD Auweter, R Fasan, L Reymond, JG Underwood, DL Black, S Pitsch, ...
The EMBO journal 25 (1), 163-173, 2006
Evolutionary history of a specialized P450 propane monooxygenase
R Fasan, YT Meharenna, CD Snow, TL Poulos, FH Arnold
Journal of molecular biology 383 (5), 1069-1080, 2008
Using a b-hairpin to mimic an a-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction
R Fasan, RLA Dias, K Moehle, O Zerbe, JW Vrijbloed, D Obrecht, ...
Angewandte Chemie-International Edition 43 (16), 2109-2112, 2004
Controlled Oxidation of Remote sp3 C–H Bonds in Artemisinin via P450 Catalysts with Fine-Tuned Regio- and Stereoselectivity
K Zhang, BM Shafer, MD Demars, HA Stern, R Fasan
Journal of the American Chemical Society 134 (45), 18695-18704, 2012
Intermolecular carbene S–H insertion catalysed by engineered myoglobin-based catalysts
V Tyagi, RB Bonn, R Fasan
Chemical science 6 (4), 2488-2494, 2015
P450-Catalyzed Intramolecular sp3 C–H Amination with Arylsulfonyl Azide Substrates
R Singh, M Bordeaux, R Fasan
ACS catalysis 4 (2), 546-552, 2014
Highly diastereo-and enantioselective synthesis of trifluoromethyl-substituted cyclopropanes via myoglobin-catalyzed transfer of trifluoromethylcarbene
A Tinoco, V Steck, V Tyagi, R Fasan
Journal of the American Chemical Society 139 (15), 5293-5296, 2017
Structure–activity studies in a family of β‐Hairpin protein epitope mimetic inhibitors of the p53–HDM2 protein–protein interaction
R Fasan, RLA Dias, K Moehle, O Zerbe, D Obrecht, PRE Mittl, MG Grütter, ...
ChemBioChem 7 (3), 515-526, 2006
Myoglobin-catalyzed intermolecular carbene N–H insertion with arylamine substrates
G Sreenilayam, R Fasan
Chemical Communications 51 (8), 1532-1534, 2015
Gram‐scale synthesis of chiral cyclopropane‐containing drugs and drug precursors with engineered myoglobin catalysts featuring complementary stereoselectivity
P Bajaj, G Sreenilayam, V Tyagi, R Fasan
Angewandte Chemie 128 (52), 16344-16348, 2016
Enzymatic C(sp3)-H Amination: P450-Catalyzed Conversion of Carbonazidates into Oxazolidinones
R Singh, JN Kolev, PA Sutera, R Fasan
ACS catalysis 5 (3), 1685-1691, 2015
Chemo-enzymatic fluorination of unactivated organic compounds
A Rentmeister, FH Arnold, R Fasan
Nature Chemical Biology 5 (1), 26-28, 2009
Intramolecular C (sp3) H amination of arylsulfonyl azides with engineered and artificial myoglobin-based catalysts
M Bordeaux, R Singh, R Fasan
Bioorganic & medicinal chemistry 22 (20), 5697-5704, 2014
Metal substitution modulates the reactivity and extends the reaction scope of myoglobin carbene transfer catalysts
G Sreenilayam, EJ Moore, V Steck, R Fasan
Advanced synthesis & catalysis 359 (12), 2076-2089, 2017
P450 fingerprinting method for rapid discovery of terpene hydroxylating P450 catalysts with diversified regioselectivity
K Zhang, S El Damaty, R Fasan
Journal of the American Chemical Society 133 (10), 3242-3245, 2011
Myoglobin‐Catalyzed C− H Functionalization of Unprotected Indoles
DA Vargas, A Tinoco, V Tyagi, R Fasan
Angewandte Chemie International Edition 57 (31), 9911-9915, 2018
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