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Ashok Sekhar
Ashok Sekhar
Assistant Professor, Indian Institute of Science Bangalore, India
Bestätigte E-Mail-Adresse bei iisc.ac.in - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
JP Brady, PJ Farber, A Sekhar, YH Lin, R Huang, A Bah, TJ Nott, ...
Proceedings of the National Academy of Sciences 114 (39), E8194-E8203, 2017
4092017
NMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformers
A Sekhar, LE Kay
Proceedings of the National Academy of Sciences 110 (32), 12867-12874, 2013
2542013
An NMR view of protein dynamics in health and disease
A Sekhar, LE Kay
Annual review of biophysics 48, 297-319, 2019
1432019
Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer
P Vallurupalli, A Sekhar, T Yuwen, LE Kay
Journal of biomolecular NMR 67, 243-271, 2017
1402017
Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways
A Sekhar, JAO Rumfeldt, HR Broom, CM Doyle, G Bouvignies, ...
elife 4, e07296, 2015
1152015
Mapping the conformation of a client protein through the Hsp70 functional cycle
A Sekhar, R Rosenzweig, G Bouvignies, LE Kay
Proceedings of the National Academy of Sciences 112 (33), 10395-10400, 2015
1032015
Hsp70 biases the folding pathways of client proteins
A Sekhar, R Rosenzweig, G Bouvignies, LE Kay
Proceedings of the National Academy of Sciences 113 (20), E2794-E2801, 2016
982016
Promiscuous binding by Hsp70 results in conformational heterogeneity and fuzzy chaperone-substrate ensembles
R Rosenzweig, A Sekhar, J Nagesh, LE Kay
Elife 6, e28030, 2017
812017
Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions
A Sekhar, A Velyvis, G Zoltsman, R Rosenzweig, G Bouvignies, LE Kay
Elife 7, e32764, 2018
802018
Understanding the mechanism of proteasome 20S core particle gating
MP Latham, A Sekhar, LE Kay
Proceedings of the National Academy of Sciences 111 (15), 5532-5537, 2014
672014
Effects of maturation on the conformational free-energy landscape of SOD1
RM Culik, A Sekhar, J Nagesh, H Deol, JAO Rumfeldt, EM Meiering, ...
Proceedings of the National Academy of Sciences 115 (11), E2546-E2555, 2018
662018
Probing the free energy landscapes of ALS disease mutants of SOD1 by NMR spectroscopy
A Sekhar, JAO Rumfeldt, HR Broom, CM Doyle, RE Sobering, ...
Proceedings of the National Academy of Sciences 113 (45), E6939-E6945, 2016
662016
Heterogeneous binding of the SH3 client protein to the DnaK molecular chaperone
JH Lee, D Zhang, C Hughes, Y Okuno, A Sekhar, S Cavagnero
Proceedings of the National Academy of Sciences 112 (31), E4206-E4215, 2015
562015
1H-Detected 13C Photo-CIDNP as a Sensitivity Enhancement Tool in Solution NMR
JH Lee, A Sekhar, S Cavagnero
Journal of the American Chemical Society 133 (21), 8062-8065, 2011
512011
Characterizing post-translational modifications and their effects on protein conformation using NMR spectroscopy
A Kumar, V Narayanan, A Sekhar
Biochemistry 59 (1), 57-73, 2019
482019
A universal pattern in the percolation and dissipation of protein structural perturbations
N Rajasekaran, A Sekhar, AN Naganathan
The journal of physical chemistry letters 8 (19), 4779-4784, 2017
412017
Defining a length scale for millisecond-timescale protein conformational exchange
A Sekhar, P Vallurupalli, LE Kay
Proceedings of the National Academy of Sciences 110 (28), 11391-11396, 2013
402013
Separating Dipolar and Chemical Exchange Magnetization Transfer Processes in 1H‐CEST
T Yuwen, A Sekhar, LE Kay
Angewandte Chemie International Edition 56 (22), 6122-6125, 2017
392017
Probing the free energy landscape of the fast-folding gpW protein by relaxation dispersion NMR
C Sanchez-Medina, A Sekhar, P Vallurupalli, M Cerminara, V Muñoz, ...
Journal of the American Chemical Society 136 (20), 7444-7451, 2014
382014
Concurrent increases and decreases in local stability and conformational heterogeneity in Cu, Zn superoxide dismutase variants revealed by temperature-dependence of amide …
CM Doyle, JA Rumfeldt, HR Broom, A Sekhar, LE Kay, EM Meiering
Biochemistry 55 (9), 1346-1361, 2016
372016
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