2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1 J Neres, RC Hartkoorn, LR Chiarelli, R Gadupudi, MR Pasca, G Mori, ... ACS chemical biology 10 (3), 705-714, 2015 | 127 | 2015 |
Shifts of faecal microbiota during sporadic colorectal carcinogenesis G Mori, S Rampelli, BS Orena, C Rengucci, G De Maio, G Barbieri, ... Scientific reports 8 (1), 1-11, 2018 | 86 | 2018 |
Mechanochemical synthesis and biological evaluation of novel isoniazid derivatives with potent antitubercular activity PFM Oliveira, B Guidetti, A Chamayou, C André-Barrès, J Madacki, ... Molecules 22 (9), 1457, 2017 | 82 | 2017 |
Thiophenecarboxamide derivatives activated by EthA kill Mycobacterium tuberculosis by inhibiting the CTP synthetase PyrG G Mori, LR Chiarelli, M Esposito, V Makarov, M Bellinzoni, RC Hartkoorn, ... Chemistry & biology 22 (7), 917-927, 2015 | 75 | 2015 |
Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents LR Chiarelli, M Mori, D Barlocco, G Beretta, A Gelain, E Pini, M Porcino, ... European journal of medicinal chemistry 155, 754-763, 2018 | 66 | 2018 |
Design, syntheses, and anti-TB activity of 1, 3-benzothiazinone azide and click chemistry products inspired by BTZ043 R Tiwari, PA Miller, LR Chiarelli, G Mori, M Šarkan, I Centárová, S Cho, ... ACS Medicinal Chemistry Letters 7 (3), 266-270, 2016 | 66 | 2016 |
Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis AL de Jesus Lopes Ribeiro, G Degiacomi, F Ewann, S Buroni, ... PloS one 6 (11), e26675, 2011 | 66 | 2011 |
New prodrugs against tuberculosis G Mori, LR Chiarelli, G Riccardi, MR Pasca Drug Discovery Today 22 (3), 519-525, 2017 | 51 | 2017 |
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth A Chollet, G Mori, C Menendez, F Rodriguez, I Fabing, MR Pasca, ... European Journal of Medicinal Chemistry 101, 218-235, 2015 | 50 | 2015 |
Synthesis of 3-heteryl substituted pyrrolidine-2, 5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis T Matviiuk, G Mori, C Lherbet, F Rodriguez, MR Pasca, M Gorichko, ... European Journal of Medicinal Chemistry 71, 46-52, 2014 | 50 | 2014 |
Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis D Albesa-Jove, LR Chiarelli, V Makarov, MR Pasca, S Urresti, G Mori, ... ACS Chemical Biology 9 (7), 1567-1575, 2014 | 44 | 2014 |
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK LR Chiarelli, G Mori, BS Orena, M Esposito, T Lane, ... Scientific reports 8 (1), 3187, 2018 | 43 | 2018 |
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis T Matviiuk, J Madacki, G Mori, BS Orena, C Menendez, A Kysil, ... European Journal of Medicinal Chemistry 123, 462-475, 2016 | 40 | 2016 |
Microbiome-immune interactions in tuberculosis G Mori, M Morrison, A Blumenthal PLoS pathogens 17 (4), e1009377, 2021 | 35 | 2021 |
New and old hot drug targets in tuberculosis L Roberto Chiarelli, G Mori, M Esposito, B Silvia Orena, M Rosalia Pasca Current medicinal chemistry 23 (33), 3813-3846, 2016 | 34 | 2016 |
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors M Esposito, S Szadocka, G Degiacomi, BS Orena, G Mori, V Piano, ... ACS Infectious Diseases 3 (6), 428-437, 2017 | 33 | 2017 |
Synthesis, oxidation potential and anti–mycobacterial activity of isoniazid and analogues: insights into the molecular isoniazid activation mechanism J Laborde, C Deraeve, L Lecoq, A Sournia‐Saquet, JL Stigliani, BS Orena, ... ChemistrySelect 1 (2), 172-179, 2016 | 28 | 2016 |
Gut microbiota analysis in postoperative lynch syndrome patients G Mori, BS Orena, I Cultrera, G Barbieri, AM Albertini, GN Ranzani, ... Frontiers in Microbiology 10, 1746, 2019 | 27 | 2019 |
Gut microbial signatures in sporadic and hereditary colorectal cancer G Mori, MR Pasca International Journal of Molecular Sciences 22 (3), 1312, 2021 | 21 | 2021 |
2-aminooxazole as a novel privileged scaffold in antitubercular medicinal chemistry E Azzali, M Girardini, G Annunziato, M Pavone, F Vacondio, G Mori, ... ACS Medicinal Chemistry Letters 11 (7), 1435-1441, 2020 | 20 | 2020 |