Codon-specific translation reprogramming promotes resistance to targeted therapy F Rapino, S Delaunay, F Rambow, Z Zhou, L Tharun, P De Tullio, O Sin, ... Nature 558 (7711), 605-609, 2018 | 238 | 2018 |
Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer S Delaunay, F Rapino, L Tharun, Z Zhou, L Heukamp, M Termathe, ... Journal of Experimental Medicine 213 (11), 2503-2523, 2016 | 177 | 2016 |
Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma M Corazzari, F Rapino, F Ciccosanti, P Giglio, M Antonioli, B Conti, ... Cell Death & Differentiation 22 (6), 946-958, 2015 | 171 | 2015 |
Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine A Ladang, F Rapino, LC Heukamp, L Tharun, K Shostak, D Hermand, ... Journal of Experimental Medicine 212 (12), 2057-2075, 2015 | 86 | 2015 |
tRNA modification: is cancer having a wobble? F Rapino, S Delaunay, Z Zhou, A Chariot, P Close Trends in cancer 3 (4), 249-252, 2017 | 56 | 2017 |
BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways F Rapino, M Jung, S Fulda Oncogene 33 (13), 1713-1724, 2014 | 52 | 2014 |
Bortezomib antagonizes microtubule-interfering drug-induced apoptosis by inhibiting G2/M transition and MCL-1 degradation F Rapino, I Naumann, S Fulda Cell death & disease 4 (11), e925-e925, 2013 | 41 | 2013 |
Translational offsetting as a mode of estrogen receptor α‐dependent regulation of gene expression J Lorent, EP Kusnadi, V van Hoef, RJ Rebello, M Leibovitch, J Ristau, ... The EMBO journal 38 (23), e101323, 2019 | 38 | 2019 |
Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate F Rapino, Z Zhou, AM Roncero Sanchez, M Joiret, C Seca, N El Hachem, ... Nature Communications 12 (1), 2170, 2021 | 34 | 2021 |
NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways F Rapino, BA Abhari, M Jung, S Fulda Cell Death & Disease 6 (3), e1692-e1692, 2015 | 26 | 2015 |
Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis A Rosu, N El Hachem, F Rapino, K Rouault-Pierre, J Jorssen, J Somja, ... Journal of Experimental Medicine 218 (3), e20200662, 2021 | 20 | 2021 |
Ribosome exit tunnel electrostatics M Joiret, F Kerff, F Rapino, P Close, L Geris Physical Review E 105 (1), 014409, 2022 | 16 | 2022 |
Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells MH Berryer, M Tegtmeyer, L Binan, V Valakh, A Nathanson, ... Iscience 26 (7), 2023 | 9 | 2023 |
Wobble uridine tRNA modification: a new vulnerability of refractory melanoma F Rapino, P Close Molecular & Cellular Oncology 5 (6), e1513725, 2018 | 8 | 2018 |
Cracking the genetic code with neural networks M Joiret, M Leclercq, G Lambrechts, F Rapino, P Close, G Louppe, ... Frontiers in Artificial Intelligence 6, 1128153, 2023 | 4 | 2023 |
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma N El-Hachem, M Leclercq, M Susaeta Ruiz, R Vanleyssem, K Shostak, ... Nature Cell Biology, 1-11, 2024 | 3 | 2024 |
A simple geometrical model of the electrostatic environment around the catalytic center of the ribosome and its significance for the elongation cycle kinetics M Joiret, F Kerff, F Rapino, P Close, L Geris Computational and Structural Biotechnology Journal 21, 3768-3795, 2023 | 2 | 2023 |
Author Correction: codon-specific translation reprogramming promotes resistance to targeted therapy F Rapino, S Delaunay, F Rambow, Z Zhou, L Tharun, P De Tullio, O Sin, ... Nature 599 (7886), E14-E14, 2021 | 2 | 2021 |
Iron‐responsive element of divalent metal transporter 1 (Dmt1) controls Notch‐mediated cell fates J Hounjet, AJ Groot, JP Piepers, O Kranenburg, DA Zwijnenburg, ... The FEBS journal 290 (24), 5811-5834, 2023 | 1 | 2023 |
Reversing the relative time courses of the peptide bond reaction with oligopeptides of different lengths and charged amino acid distributions in the ribosome exit tunnel M Joiret, F Kerff, F Rapino, P Close, L Geris Computational and Structural Biotechnology Journal, 2024 | | 2024 |