The short chain fatty acid butyrate imprints an antimicrobial program in macrophages J Schulthess, S Pandey, M Capitani, KC Rue-Albrecht, I Arnold, ... Immunity 50 (2), 432-445. e7, 2019 | 725 | 2019 |
Distinct fibroblast subsets drive inflammation and damage in arthritis AP Croft, J Campos, K Jansen, JD Turner, J Marshall, M Attar, L Savary, ... Nature 570 (7760), 246-251, 2019 | 646 | 2019 |
Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex JD Pereira, SN Sansom, J Smith, MW Dobenecker, A Tarakhovsky, ... Proceedings of the National Academy of Sciences 107 (36), 15957-15962, 2010 | 478 | 2010 |
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis SN Sansom, DS Griffiths, A Faedo, DJ Kleinjan, Y Ruan, J Smith, ... PLoS genetics 5 (6), e1000511, 2009 | 456 | 2009 |
A highly efficient human pluripotent stem cell microglia model displays a neuronal-co-culture-specific expression profile and inflammatory response W Haenseler, SN Sansom, J Buchrieser, SE Newey, CS Moore, ... Stem cell reports 8 (6), 1727-1742, 2017 | 454 | 2017 |
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis S Alivernini, L MacDonald, A Elmesmari, S Finlay, B Tolusso, MR Gigante, ... Nature medicine 26 (8), 1295-1306, 2020 | 388 | 2020 |
Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia SN Sansom, N Shikama-Dorn, S Zhanybekova, G Nusspaumer, ... Genome research 24 (12), 1918-1931, 2014 | 346 | 2014 |
The long non‐coding RNA Paupar regulates the expression of both local and distal genes KW Vance, SN Sansom, S Lee, V Chalei, L Kong, SE Cooper, PL Oliver, ... The EMBO journal 33 (4), 296-311, 2014 | 230 | 2014 |
Chromatin regulation by BAF170 controls cerebral cortical size and thickness TC Tuoc, S Boretius, SN Sansom, ME Pitulescu, J Frahm, FJ Livesey, ... Developmental cell 25 (3), 256-269, 2013 | 192 | 2013 |
Gradients in the brain: the control of the development of form and function in the cerebral cortex SN Sansom, FJ Livesey Cold Spring Harbor perspectives in biology 1 (2), a002519, 2009 | 174 | 2009 |
The long non-coding RNA Dali is an epigenetic regulator of neural differentiation V Chalei, SN Sansom, L Kong, S Lee, JF Montiel, KW Vance, CP Ponting elife 3, e04530, 2014 | 166 | 2014 |
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ... Cell 185 (5), 916-938. e58, 2022 | 159 | 2022 |
An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease Y Peng, SL Felce, D Dong, F Penkava, AJ Mentzer, X Yao, G Liu, Z Yin, ... Nature immunology 23 (1), 50-61, 2022 | 138 | 2022 |
Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus DJ Downes, AR Cross, P Hua, N Roberts, R Schwessinger, AJ Cutler, ... Nature genetics 53 (11), 1606-1615, 2021 | 135 | 2021 |
IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies M Friedrich, M Pohin, MA Jackson, I Korsunsky, SJ Bullers, ... Nature Medicine 27 (11), 1970-1981, 2021 | 134 | 2021 |
Reversible block of mouse neural stem cell differentiation in the absence of dicer and microRNAs T Andersson, S Rahman, SN Sansom, JM Alsiö, M Kaneda, J Smith, ... PloS one 5 (10), e13453, 2010 | 87 | 2010 |
Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb D Mi, CB Carr, PA Georgala, YT Huang, MN Manuel, E Jeanes, E Niisato, ... Neuron 78 (2), 269-284, 2013 | 85 | 2013 |
Interferon regulatory factor 5 controls necrotic core formation in atherosclerotic lesions by impairing efferocytosis AN Seneviratne, A Edsfeldt, JE Cole, C Kassiteridi, M Swart, I Park, ... Circulation 136 (12), 1140-1154, 2017 | 83 | 2017 |
GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis D Regan-Komito, JW Swann, P Demetriou, ES Cohen, NJ Horwood, ... Nature communications 11 (1), 155, 2020 | 80 | 2020 |
CGAT: computational genomics analysis toolkit D Sims, NE Ilott, SN Sansom, IM Sudbery, JS Johnson, KA Fawcett, ... Bioinformatics 30 (9), 1290-1291, 2014 | 76 | 2014 |