Causes and consequences of the loss of serotonergic presynapses elicited by the consumption of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) and its congeners G Huether, D Zhou, E Rüther Journal of Neural Transmission 104, 771-794, 1997 | 168 | 1997 |
Mechanisms Underlying Hypoxia Tolerance in Drosophila melanogaster: hairy as a Metabolic Switch D Zhou, J Xue, JCK Lai, NJ Schork, KP White, GG Haddad PLoS genetics 4 (10), e1000221, 2008 | 166 | 2008 |
Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders D Zhou, N Udpa, R Ronen, T Stobdan, J Liang, O Appenzeller, HW Zhao, ... The American Journal of Human Genetics 93 (3), 452-462, 2013 | 154 | 2013 |
Experimental selection of hypoxia-tolerant Drosophila melanogaster D Zhou, N Udpa, M Gersten, DAW Visk, A Bashir, J Xue, KA Frazer, ... Proceedings of the National Academy of Sciences 108 (6), 2349-2354, 2011 | 138 | 2011 |
Acute disruption of select steroid receptor coactivators prevents reproductive behavior in rats and unmasks genetic adaptation in knockout mice EM Apostolakis, M Ramamurphy, D Zhou, S Oñate, BW O’Malley Molecular Endocrinology 16 (7), 1511-1523, 2002 | 136 | 2002 |
High-altitude adaptation in humans: from genomics to integrative physiology P Azad, T Stobdan, D Zhou, I Hartley, A Akbari, V Bafna, GG Haddad Journal of Molecular Medicine 95, 1269-1282, 2017 | 122 | 2017 |
Intermittent hypoxia and hypercapnia, a hallmark of obstructive sleep apnea, alters the gut microbiome and metabolome A Tripathi, AV Melnik, J Xue, O Poulsen, MJ Meehan, G Humphrey, ... Msystems 3 (3), 10.1128/msystems. 00020-18, 2018 | 115 | 2018 |
Experimental selection for Drosophila survival in extremely low O2 environment. D Zhou, J Xue, J Chen, P Morcillo, JD Lambert, KP White, GG Haddad PLoS ONE 2 (5), 2007 | 107 | 2007 |
Gene expression and phenotypic characterization of mouse heart after chronic constant or intermittent hypoxia C Fan, DA Iacobas, D Zhou, Q Chen, JK Lai, O Gavrialov, GG Haddad Physiological genomics 22 (3), 292-307, 2005 | 101 | 2005 |
Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes N Udpa, R Ronen, D Zhou, J Liang, T Stobdan, O Appenzeller, Y Yin, ... Genome Biol 15 (2), R36, 2014 | 100 | 2014 |
Distinct mechanisms underlying tolerance to intermittent and constant hypoxia in Drosophila melanogaster P Azad, D Zhou, E Russo, GG Haddad PLoS One 4 (4), e5371, 2009 | 94 | 2009 |
Hypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakage SS Ali, M Hsiao, HW Zhao, LL Dugan, GG Haddad, D Zhou PloS one 7 (5), e36801, 2012 | 93 | 2012 |
Intermittent hypoxia and hypercapnia accelerate atherosclerosis, partially via trimethylamine-oxide J Xue, D Zhou, O Poulsen, T Imamura, YH Hsiao, TH Smith, A Malhotra, ... American journal of respiratory cell and molecular biology 57 (5), 581-588, 2017 | 88 | 2017 |
Influence of olfactory bulbectomy and subsequent imipramine treatment on 5-hydroxytryptaminergic presynapses in the rat frontal cortex: behavioural correlates G Grecksch, D Zhou, C Franke, U Schröder, B Sabel, A Becker, G Huether British journal of pharmacology 122 (8), 1725, 1997 | 84 | 1997 |
Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysis JD Feala, L Coquin, D Zhou, GG Haddad, G Paternostro, AD McCulloch BMC systems biology 3, 1-15, 2009 | 81 | 2009 |
Long-term food restriction down-regulates the density of serotonin transporters in the rat frontal cortex G Huether, D Zhou, S Schmidt, J Wiltfang, E Rüther Biological psychiatry 41 (12), 1174-1180, 1997 | 79 | 1997 |
Antimicrobial peptides increase tolerance to oxidant stress in Drosophila melanogaster HW Zhao, D Zhou, GG Haddad Journal of Biological Chemistry 286 (8), 6211-6218, 2011 | 78 | 2011 |
Long-lasting changes in DNA methylation following short-term hypoxic exposure in primary hippocampal neuronal cultures. I Hartley, FF Elkhoury, SJ Heon, B Xie, X Gu, Y Gao, D Zhou, GG Haddad PLoS One 8 (10), e77859, 2013 | 74 | 2013 |
Serotonergic hyperinnervation of the frontal cortex in an animal model of depression, the bulbectomized rat D Zhou, G Grecksch, A Becker, C Frank, J Pilz, G Huether Journal of neuroscience research 54 (1), 109-116, 1998 | 67 | 1998 |
CB1 cannabinoid receptor‐mediated neurite remodeling in mouse neuroblastoma N1E‐115 cells D Zhou, ZH Song Journal of neuroscience research 65 (4), 346-353, 2001 | 57 | 2001 |