| TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo JH Shim, C Xiao, AE Paschal, ST Bailey, P Rao, MS Hayden, KY Lee, ... Genes & development 19 (22), 2668-2681, 2005 | 882 | 2005 |
| Osteoblast-osteoclast communication and bone homeostasis JM Kim, C Lin, Z Stavre, MB Greenblatt, JH Shim Cells 9 (9), 2073, 2020 | 669 | 2020 |
| T-bet represses TH17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt V Lazarevic, X Chen, JH Shim, ES Hwang, E Jang, AN Bolm, M Oukka, ... Nature immunology 12 (1), 96-104, 2011 | 509 | 2011 |
| Discovery of a periosteal stem cell mediating intramembranous bone formation S Debnath, AR Yallowitz, J McCormick, S Lalani, T Zhang, R Xu, NA Li, ... Nature 562 (7725), 133-139, 2018 | 486 | 2018 |
| The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice MB Greenblatt, JH Shim, W Zou, D Sitara, M Schweitzer, D Hu, S Lotinun, ... The Journal of clinical investigation 120 (7), 2457-2473, 2010 | 421 | 2010 |
| PDK1 nucleates T cell receptor-induced signaling complex for NF-κB activation KY Lee, F D'Acquisto, MS Hayden, JH Shim, S Ghosh Science 308 (5718), 114-118, 2005 | 311 | 2005 |
| Targeting skeletal endothelium to ameliorate bone loss R Xu, A Yallowitz, A Qin, Z Wu, DY Shin, JM Kim, S Debnath, G Ji, ... Nature medicine 24 (6), 823-833, 2018 | 264 | 2018 |
| Mitogen-activated protein kinase pathways in osteoblasts MB Greenblatt, JH Shim, LH Glimcher Annual review of cell and developmental biology 29, 63-79, 2013 | 246 | 2013 |
| TAK1 is an essential regulator of BMP signalling in cartilage JH Shim, MB Greenblatt, M Xie, MD Schneider, W Zou, B Zhai, S Gygi, ... The EMBO journal 28 (14), 2028-2041, 2009 | 166 | 2009 |
| CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis JH Shim, C Xiao, MS Hayden, KY Lee, ES Trombetta, M Pypaert, A Nara, ... The Journal of cell biology 172 (7), 1045-1056, 2006 | 137 | 2006 |
| The ERK MAPK pathway is essential for skeletal development and homeostasis JM Kim, YS Yang, KH Park, H Oh, MB Greenblatt, JH Shim International journal of molecular sciences 20 (8), 1803, 2019 | 121 | 2019 |
| H2O2-dependent hyperoxidation of peroxiredoxin 6 (Prdx6) plays a role in cellular toxicity via up-regulation of iPLA2 activity SY Kim, HY Jo, MH Kim, Y Cha, SW Choi, JH Shim, TJ Kim, KY Lee Journal of biological chemistry 283 (48), 33563-33568, 2008 | 121 | 2008 |
| Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis C Xiao, J Shim, M Klüppel, SSM Zhang, C Dong, RA Flavell, XY Fu, ... Genes & development 17 (23), 2933-2949, 2003 | 119 | 2003 |
| The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid W Zou, X Chen, JH Shim, Z Huang, N Brady, D Hu, R Drapp, K Sigrist, ... Nature cell biology 13 (1), 59-65, 2011 | 115 | 2011 |
| Bone loss in rheumatoid arthritis: basic mechanisms and clinical implications J Shim, Z Stavre, EM Gravallese Calcified Tissue International 102, 533-546, 2018 | 111 | 2018 |
| Zinc inhibits osteoclast differentiation by suppression of Ca2+-Calcineurin-NFATc1 signaling pathway KH Park, B Park, DS Yoon, SH Kwon, DM Shin, JW Lee, HG Lee, JH Shim, ... Cell Communication and Signaling 11, 1-12, 2013 | 96 | 2013 |
| Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex H Mendoza, DG Campbell, K Burness, J Hastie, N Ronkina, JH Shim, ... Biochemical Journal 409 (3), 711-722, 2008 | 91 | 2008 |
| TAK1-ECSIT-TRAF6 complex plays a key role in the TLR4 signal to activate NF-κB SM Wi, G Moon, J Kim, ST Kim, JH Shim, E Chun, KY Lee Journal of Biological Chemistry 289 (51), 35205-35214, 2014 | 89 | 2014 |
| Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis YS Yang, J Xie, D Wang, JM Kim, PWL Tai, E Gravallese, G Gao, JH Shim Nature communications 10 (1), 2958, 2019 | 79 | 2019 |
| A novel ubiquitin-like domain in IκB kinase β is required for functional activity of the kinase MJ May, SE Larsen, JH Shim, LA Madge, S Ghosh Journal of Biological Chemistry 279 (44), 45528-45539, 2004 | 77 | 2004 |
