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Adam E. Locke
Adam E. Locke
Senior Director, Statistical Genetics, Regeneron Genetics Center
Verified email at regeneron.com
Title
Cited by
Cited by
Year
Genetic studies of body mass index yield new insights for obesity biology
AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ...
Nature 518 (7538), 197-206, 2015
48022015
Next-generation genotype imputation service and methods
S Das, L Forer, S Schönherr, C Sidore, AE Locke, A Kwong, SI Vrieze, ...
Nature genetics 48 (10), 1284-1287, 2016
33552016
Defining the role of common variation in the genomic and biological architecture of adult human height
AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ...
Nature genetics 46 (11), 1173-1186, 2014
21262014
New genetic loci link adipose and insulin biology to body fat distribution
D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ...
Nature 518 (7538), 187-196, 2015
16552015
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
A Mahajan, D Taliun, M Thurner, NR Robertson, JM Torres, NW Rayner, ...
Nature genetics 50 (11), 1505-1513, 2018
16202018
The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
12502016
Rare and low-frequency coding variants alter human adult height
E Marouli, M Graff, C Medina-Gomez, KS Lo, AR Wood, TR Kjaer, RS Fine, ...
Nature 542 (7640), 186-190, 2017
6572017
Quality control and conduct of genome-wide association meta-analyses
TW Winkler, FR Day, DC Croteau-Chonka, AR Wood, AE Locke, R Mägi, ...
Nature protocols 9 (5), 1192-1212, 2014
5322014
Exome sequencing and analysis of 454,787 UK Biobank participants
JD Backman, AH Li, A Marcketta, D Sun, J Mbatchou, MD Kessler, ...
Nature 599 (7886), 628-634, 2021
5162021
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
JC Randall, TW Winkler, Z Kutalik, SI Berndt, AU Jackson, KL Monda, ...
PLoS genetics 9 (6), e1003500, 2013
4762013
The power of genetic diversity in genome-wide association studies of lipids
SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ...
Nature 600 (7890), 675-679, 2021
4602021
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ...
Nature genetics 47 (12), 1415-1425, 2015
4212015
Ethnicity, sex, and the incidence of congenital heart defects: a report from the National Down Syndrome Project
SB Freeman, LH Bean, EG Allen, SW Tinker, AE Locke, C Druschel, ...
Genetics in Medicine 10 (3), 173-180, 2008
3932008
A saturated map of common genetic variants associated with human height
L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ...
Nature 610 (7933), 704-712, 2022
3702022
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
V Turcot, Y Lu, HM Highland, C Schurmann, AE Justice, RS Fine, ...
Nature genetics 50 (1), 26-41, 2018
3402018
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ...
Nature genetics 54 (5), 560-572, 2022
3282022
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
CG Boer, K Hatzikotoulas, L Southam, L Stefánsdóttir, Y Zhang, ...
Cell 184 (18), 4784-4818. e17, 2021
3212021
Genetic evidence of assortative mating in humans
MR Robinson, A Kleinman, M Graff, AAE Vinkhuyzen, D Couper, ...
Nature Human Behaviour 1 (1), 0016, 2017
3182017
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Y Lu, FR Day, S Gustafsson, ML Buchkovich, J Na, V Bataille, ...
Nature communications 7 (1), 10495, 2016
2992016
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol
LA Lange, Y Hu, H Zhang, C Xue, EM Schmidt, ZZ Tang, C Bizon, ...
The American Journal of Human Genetics 94 (2), 233-245, 2014
2412014
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