| Macrophage phenotype and bioenergetics are controlled by oxidized phospholipids identified in lean and obese adipose tissue V Serbulea, CM Upchurch, MS Schappe, P Voigt, DE DeWeese, ... Proceedings of the National Academy of Sciences 115 (27), E6254-E6263, 2018 | 110 | 2018 |
| Macrophages sensing oxidized DAMPs reprogram their metabolism to support redox homeostasis and inflammation through a TLR2-Syk-ceramide dependent mechanism V Serbulea, CM Upchurch, KW Ahern, G Bories, P Voigt, DE DeWeese, ... Molecular metabolism 7, 23-34, 2018 | 47 | 2018 |
| Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2 AJB Kreutzberger, V Kiessling, CA Doyle, N Schenk, CM Upchurch, ... Elife 9, e62506, 2020 | 30 | 2020 |
| Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels S Senthivinayagam, V Serbulea, CM Upchurch, ... Molecular Metabolism 44, 101130, 2021 | 21 | 2021 |
| Carbon nanodots as molecular scaffolds for development of antimicrobial agents M Ngu-Schwemlein, SF Chin, R Hileman, C Drozdowski, C Upchurch, ... Bioorganic & medicinal chemistry letters 26 (7), 1745-1749, 2016 | 19 | 2016 |
| Mitochondrial Ca2+ signaling is an electrometabolic switch to fuel phagosome killing PV Seegren, TK Downs, ME Stremska, LR Harper, R Cao, RJ Olson, ... Cell reports 33 (8), 2020 | 16 | 2020 |
| Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism S Yeudall, CM Upchurch, PV Seegren, CM Pavelec, J Greulich, ... Science Advances 8 (47), eabq1984, 2022 | 15 | 2022 |
| Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis CM Upchurch, S Yeudall, CM Pavelec, D Merk, J Greulich, ... Science Advances 8 (28), eabn0050, 2022 | 13 | 2022 |
| BAFF antagonism via the BAFF receptor 3 binding site attenuates BAFF 60-mer-induced classical NF-κB signaling and metabolic reprogramming of B cells MD Lempicki, S Paul, V Serbulea, CM Upchurch, S Sahu, JA Gray, ... Cellular Immunology 381, 104603, 2022 | 2 | 2022 |
| Impact of a short-term low calorie diet alone or with interval exercise on quality of life and oxidized phospholipids in obese females NM Gilbertson, NZM Eichner, JM Gaitán, JM Pirtle, JL Kirby, CM Upchurch, ... Physiology & behavior 246, 113706, 2022 | 2 | 2022 |
| Biologically active lipids in vascular biology C Upchurch, N Leitinger Fundamentals of Vascular Biology, 171-193, 2019 | 2 | 2019 |
| The clinical relevance of heme detoxification by the macrophage heme oxygenase system S Yeudall, CM Upchurch, N Leitinger Frontiers in Immunology 15, 1379967, 2024 | 1 | 2024 |
| Endocannabinoid biosynthetic enzymes regulate pain response via LKB1–AMPK signaling M Chen, M Shin, TB Ware, G Donvito, KH Muchhala, R Mischel, ... Proceedings of the National Academy of Sciences 120 (52), e2304900120, 2023 | | 2023 |
Vlad SerbuleaResearch Assistant Professor of PharmacologyBestätigte E-Mail-Adresse bei virginia.edu
