Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine K Cadwell, KK Patel, NS Maloney, TC Liu, ACY Ng, CE Storer, RD Head, ... Cell 141 (7), 1135-1145, 2010 | 992 | 2010 |
Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial BH Park, T Hwang, TC Liu, DY Sze, JS Kim, HC Kwon, SY Oh, SY Han, ... The lancet oncology 9 (6), 533-542, 2008 | 599 | 2008 |
Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress TC Liu, E Galanis, D Kirn Nature clinical practice Oncology 4 (2), 101-117, 2007 | 559 | 2007 |
Human glioblastoma–derived cancer stem cells: Establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors H Wakimoto, S Kesari, CJ Farrell, WT Curry Jr, C Zaupa, M Aghi, T Kuroda, ... Cancer research 69 (8), 3472-3481, 2009 | 410 | 2009 |
Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense KG Lassen, P Kuballa, KL Conway, KK Patel, CE Becker, JM Peloquin, ... Proceedings of the National Academy of Sciences 111 (21), 7741-7746, 2014 | 398 | 2014 |
Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy AL Kau, JD Planer, J Liu, S Rao, T Yatsunenko, I Trehan, MJ Manary, ... Science translational medicine 7 (276), 276ra24-276ra24, 2015 | 382 | 2015 |
IL-6 stimulates intestinal epithelial proliferation and repair after injury KA Kuhn, NA Manieri, TC Liu, TS Stappenbeck PloS one 9 (12), e114195, 2014 | 290 | 2014 |
Genetics and pathogenesis of inflammatory bowel disease TC Liu, TS Stappenbeck Annual Review of Pathology: Mechanisms of Disease 11, 127-148, 2016 | 274 | 2016 |
The targeted oncolytic poxvirus JX-594 demonstrates antitumoral, antivascular, and anti-HBV activities in patients with hepatocellular carcinoma TC Liu, T Hwang, BH Park, J Bell, DH Kirn Molecular therapy 16 (9), 1637-1642, 2008 | 234 | 2008 |
Gene therapy progress and prospects cancer: oncolytic viruses TC Liu, D Kirn Gene therapy 15 (12), 877-884, 2008 | 212 | 2008 |
Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease KL VanDussen, TC Liu, D Li, F Towfic, N Modiano, R Winter, ... Gastroenterology 146 (1), 200-209, 2014 | 211 | 2014 |
Alternative lengthening of telomeres and loss of DAXX/ATRX expression predicts metastatic disease and poor survival in patients with pancreatic neuroendocrine tumors AD Singhi, TC Liu, JL Roncaioli, D Cao, HJ Zeh, AH Zureikat, A Tsung, ... Clinical Cancer Research 23 (2), 600-609, 2017 | 204 | 2017 |
E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models Y Wang, G Hallden, R Hill, A Anand, TC Liu, J Francis, G Brooks, ... Nature biotechnology 21 (11), 1328-1335, 2003 | 190 | 2003 |
A mechanistic proof-of-concept clinical trial with JX-594, a targeted multi-mechanistic oncolytic poxvirus, in patients with metastatic melanoma TH Hwang, A Moon, J Burke, A Ribas, J Stephenson, CJ Breitbach, ... Molecular Therapy 19 (10), 1913-1922, 2011 | 178 | 2011 |
Systemic efficacy with oncolytic virus therapeutics: clinical proof-of-concept and future directions TC Liu, D Kirn Cancer research 67 (2), 429-432, 2007 | 159 | 2007 |
Inflammatory fibroid polyps of the gastrointestinal tract: spectrum of clinical, morphologic, and immunohistochemistry features TC Liu, MT Lin, EA Montgomery, AD Singhi The American journal of surgical pathology 37 (4), 586-592, 2013 | 155 | 2013 |
Long-term culture captures injury-repair cycles of colonic stem cells Y Wang, IL Chiang, TE Ohara, S Fujii, J Cheng, BD Muegge, A Ver Heul, ... Cell 179 (5), 1144-1159. e15, 2019 | 150 | 2019 |
Debaryomyces is enriched in Crohn’s disease intestinal tissue and impairs healing in mice U Jain, AM Ver Heul, S Xiong, MH Gregory, EG Demers, JT Kern, CW Lai, ... Science 371 (6534), 1154-1159, 2021 | 148 | 2021 |
Deep learning global glomerulosclerosis in transplant kidney frozen sections JN Marsh, MK Matlock, S Kudose, TC Liu, TS Stappenbeck, JP Gaut, ... IEEE transactions on medical imaging 37 (12), 2718-2728, 2018 | 147 | 2018 |
Novel immunocompetent murine tumor models for the assessment of replication-competent oncolytic adenovirus efficacy G Halldén, R Hill, Y Wang, A Anand, TC Liu, NR Lemoine, J Francis, ... Molecular Therapy 8 (3), 412-424, 2003 | 127 | 2003 |