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Jiazhi Hu
Jiazhi Hu
Assistant professor, Peking University
Bestätigte E-Mail-Adresse bei pku.edu.cn
Titel
Zitiert von
Zitiert von
Jahr
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
RL Frock, J Hu, RM Meyers, YJ Ho, E Kii, FW Alt
Nature biotechnology 33 (2), 179-186, 2015
7782015
Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability
FL Meng, Z Du, A Federation, J Hu, Q Wang, KR Kieffer-Kwon, ...
Cell 159 (7), 1538-1548, 2014
2702014
Detecting DNA double-stranded breaks in mammalian genomes by linear amplification–mediated high-throughput genome-wide translocation sequencing
J Hu, RM Meyers, J Dong, RA Panchakshari, FW Alt, RL Frock
Nature protocols 11 (5), 853-871, 2016
2422016
CRISPR/Cas9-mediated targeted chromosome elimination
E Zuo, X Huo, X Yao, X Hu, Y Sun, J Yin, B He, X Wang, L Shi, J Ping, ...
Genome biology 18, 1-18, 2017
2092017
The intra-S phase checkpoint targets Dna2 to prevent stalled replication forks from reversing
J Hu, L Sun, F Shen, Y Chen, Y Hua, Y Liu, M Zhang, Y Hu, Q Wang, ...
Cell 149 (6), 1221-1232, 2012
1982012
Chromosomal loop domains direct the recombination of antigen receptor genes
J Hu, Y Zhang, L Zhao, RL Frock, Z Du, RM Meyers, F Meng, DG Schatz, ...
Cell 163 (4), 947-959, 2015
1612015
Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching
J Dong, RA Panchakshari, T Zhang, Y Zhang, J Hu, SA Volpi, RM Meyers, ...
Nature 525 (7567), 134-139, 2015
1142015
Global detection of DNA repair outcomes induced by CRISPR-Cas9
M Liu, W Zhang, C Xin, J Yin, Y Shang, C Ai, J Li, F Meng, J Hu
Nucleic Acids Research, 2021
822021
Optimizing genome editing strategy by primer-extension-mediated sequencing
J Yin, M Liu, Y Liu, J Wu, T Gan, W Zhang, Y Li, Y Zhou, J Hu
Cell discovery 5 (1), 18, 2019
782019
Comprehensive assessment of miniature CRISPR-Cas12f nucleases for gene disruption
C Xin, J Yin, S Yuan, L Ou, M Liu, W Zhang, J Hu
Nature communications 13 (1), 5623, 2022
712022
Cas9 exo-endonuclease eliminates chromosomal translocations during genome editing
J Yin, R Lu, C Xin, Y Wang, X Ling, D Li, W Zhang, M Liu, W Xie, L Kong, ...
Nature communications 13 (1), 1204, 2022
682022
Highly sensitive and unbiased approach for elucidating antibody repertoires
SG Lin, Z Ba, Z Du, Y Zhang, J Hu, FW Alt
Proceedings of the National Academy of Sciences 113 (28), 7846-7851, 2016
662016
Direct visualization of RNA-DNA primer removal from Okazaki fragments provides support for flap cleavage and exonucleolytic pathways in eukaryotic cells
B Liu, J Hu, J Wang, D Kong
Journal of Biological Chemistry 292 (12), 4777-4788, 2017
612017
ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells
X Liu, T Liu, Y Shang, P Dai, W Zhang, BJ Lee, M Huang, D Yang, Q Wu, ...
Cell research 30 (9), 732-744, 2020
562020
Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates
X Ling, L Chang, H Chen, X Gao, J Yin, Y Zuo, Y Huang, B Zhang, J Hu, ...
Molecular Cell 81 (22), 4747-4756. e7, 2021
452021
Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development
L Zhao, RL Frock, Z Du, J Hu, L Chen, MS Krangel, FW Alt
Journal of Experimental Medicine 213 (9), 1921-1936, 2016
442016
In-depth assessment of the PAM compatibility and editing activities of Cas9 variants
W Zhang, J Yin, Z Zhang-Ding, C Xin, M Liu, Y Wang, C Ai, J Hu
Nucleic Acids Research 49 (15), 8785-8795, 2021
432021
The deubiquitinase USP38 promotes NHEJ repair through regulation of HDAC1 activity and regulates cancer cell response to genotoxic insults
Y Yang, C Yang, T Li, S Yu, T Gan, J Hu, J Cui, X Zheng
Cancer research 80 (4), 719-731, 2020
392020
Transcription shapes DNA replication initiation to preserve genome integrity
Y Liu, C Ai, T Gan, J Wu, Y Jiang, X Liu, R Lu, N Gao, Q Li, X Ji, J Hu
Genome biology 22 (1), 176, 2021
342021
Developmental propagation of V (D) J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes
J Hu, S Tepsuporn, RM Meyers, M Gostissa, FW Alt
Proceedings of the National Academy of Sciences 111 (28), 10269-10274, 2014
342014
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