Structural insight into nascent polypeptide chain–mediated translational stalling B Seidelt, CA Innis, DN Wilson, M Gartmann, JP Armache, E Villa, ... Science 326 (5958), 1412-1415, 2009 | 325 | 2009 |
Revisiting the structures of several antibiotics bound to the bacterial ribosome D Bulkley, CA Innis, G Blaha, TA Steitz Proceedings of the National Academy of Sciences 107 (40), 17158-17163, 2010 | 301 | 2010 |
A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome YS Polikanov, TA Steitz, CA Innis Nature structural & molecular biology 21 (9), 787-793, 2014 | 236 | 2014 |
The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex AC Seefeldt, F Nguyen, S Antunes, N Pérébaskine, M Graf, S Arenz, ... Nature structural & molecular biology 22 (6), 470-475, 2015 | 182 | 2015 |
Evolutionary trace analysis of TGF-β and related growth factors: implications for site-directed mutagenesis CA Innis, J Shi, TL Blundell Protein Engineering 13 (12), 839-847, 2000 | 179 | 2000 |
Proline-rich antimicrobial peptides targeting protein synthesis M Graf, M Mardirossian, F Nguyen, AC Seefeldt, G Guichard, M Scocchi, ... Natural product reports 34 (7), 702-711, 2017 | 176 | 2017 |
Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling D Sohmen, S Chiba, N Shimokawa-Chiba, CA Innis, O Berninghausen, ... Nature communications 6 (1), 6941, 2015 | 133 | 2015 |
The dolphin proline-rich antimicrobial peptide Tur1A inhibits protein synthesis by targeting the bacterial ribosome M Mardirossian, N Pérébaskine, M Benincasa, S Gambato, S Hofmann, ... Cell chemical biology 25 (5), 530-539. e7, 2018 | 112 | 2018 |
A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest S Arenz, LV Bock, M Graf, CA Innis, R Beckmann, H Grubmüller, ... Nature communications 7 (1), 12026, 2016 | 112 | 2016 |
Structure of the mammalian antimicrobial peptide Bac7 (1–16) bound within the exit tunnel of a bacterial ribosome AC Seefeldt, M Graf, N Pérébaskine, F Nguyen, S Arenz, M Mardirossian, ... Nucleic acids research 44 (5), 2429-2438, 2016 | 110 | 2016 |
Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis FF Yin, S Bailey, CA Innis, M Ciubotaru, S Kamtekar, TA Steitz, DG Schatz Nature structural & molecular biology 16 (5), 499-508, 2009 | 98 | 2009 |
Prediction of functional sites in proteins using conserved functional group analysis CA Innis, AP Anand, R Sowdhamini Journal of molecular biology 337 (4), 1053-1068, 2004 | 70 | 2004 |
Protein-protein interactions in receptor activation and intracellular signalling TL Blundell, DF Burke, D Chirgadze, V Dhanaraj, M Hyvönen, CA Innis, ... Walter de Gruyter 381 (9-10), 955-959, 2000 | 70 | 2000 |
Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding CA Innis, M Hyvönen Journal of Biological Chemistry 278 (41), 39969-39977, 2003 | 65 | 2003 |
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics B Beckert, EC Leroy, S Sothiselvam, LV Bock, MS Svetlov, M Graf, ... Nature Communications 12 (1), 4466, 2021 | 54 | 2021 |
Sequence‐structure homology recognition by iterative alignment refinement and comparative modeling MG Williams, H Shirai, J Shi, HG Nagendra, J Mueller, K Mizuguchi, ... Proteins: Structure, Function, and Bioinformatics 45 (S5), 92-97, 2001 | 51 | 2001 |
Ornithine capture by a translating ribosome controls bacterial polyamine synthesis A Herrero del Valle, B Seip, I Cervera-Marzal, G Sacheau, AC Seefeldt, ... Nature microbiology 5 (4), 554-561, 2020 | 48 | 2020 |
siteFiNDER| 3D: a web-based tool for predicting the location of functional sites in proteins CA Innis Nucleic acids research 35 (suppl_2), W489-W494, 2007 | 45 | 2007 |
How widespread is metabolite sensing by ribosome-arresting nascent peptides? B Seip, CA Innis Journal of molecular biology 428 (10), 2217-2227, 2016 | 37 | 2016 |
Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling AX van der Stel, ER Gordon, A Sengupta, AK Martínez, D Klepacki, ... Nature Communications 12 (1), 5340, 2021 | 25 | 2021 |