Heritable gene targeting in zebrafish using customized TALENs P Huang, A Xiao, M Zhou, Z Zhu, S Lin, B Zhang Nature biotechnology 29 (8), 699-700, 2011 | 903 | 2011 |
Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish A Xiao, Z Wang, Y Hu, Y Wu, Z Luo, Z Yang, Y Zu, W Li, P Huang, X Tong, ... Nucleic acids research 41 (14), e141-e141, 2013 | 507 | 2013 |
TALEN-mediated precise genome modification by homologous recombination in zebrafish Y Zu, X Tong, Z Wang, D Liu, R Pan, Z Li, Y Hu, Z Luo, P Huang, Q Wu, ... Nature methods 10 (4), 329-331, 2013 | 448 | 2013 |
Efficient and specific modifications of the Drosophila genome by means of an easy TALEN strategy J Liu, C Li, Z Yu, P Huang, H Wu, C Wei, N Zhu, Y Shen, Y Chen, B Zhang, ... Journal of genetics and genomics 39 (5), 209-215, 2012 | 293 | 2012 |
Unlinking an lncRNA from its associated cis element VR Paralkar, CC Taborda, P Huang, Y Yao, AV Kossenkov, R Prasad, ... Molecular cell 62 (1), 104-110, 2016 | 262 | 2016 |
Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish L Wen, W Wei, W Gu, P Huang, X Ren, Z Zhang, Z Zhu, S Lin, B Zhang Developmental biology 314 (1), 84-92, 2008 | 217 | 2008 |
Chromatin structure dynamics during the mitosis-to-G1 phase transition H Zhang, DJ Emerson, TG Gilgenast, KR Titus, Y Lan, P Huang, D Zhang, ... Nature 576 (7785), 158-162, 2019 | 192 | 2019 |
The BET protein BRD2 cooperates with CTCF to enforce transcriptional and architectural boundaries SC Hsu, TG Gilgenast, CR Bartman, CR Edwards, AJ Stonestrom, ... Molecular cell 66 (1), 102-116. e7, 2017 | 143 | 2017 |
Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element P Huang, CA Keller, B Giardine, JD Grevet, JOJ Davies, JR Hughes, ... Genes & development 31 (16), 1704-1713, 2017 | 130 | 2017 |
Functions of BET proteins in erythroid gene expression AJ Stonestrom, SC Hsu, KS Jahn, P Huang, CA Keller, BM Giardine, ... Blood, The Journal of the American Society of Hematology 125 (18), 2825-2834, 2015 | 120 | 2015 |
Reverse genetic approaches in zebrafish P Huang, Z Zhu, S Lin, B Zhang Journal of Genetics and Genomics 39 (9), 421-433, 2012 | 119 | 2012 |
A hyperactive transcriptional state marks genome reactivation at the mitosis–G1 transition CCS Hsiung, CR Bartman, P Huang, P Ginart, AJ Stonestrom, CA Keller, ... Genes & development 30 (12), 1423-1439, 2016 | 116 | 2016 |
Dynamic enhancer–gene body contacts during transcription elongation K Lee, CCS Hsiung, P Huang, A Raj, GA Blobel Genes & development 29 (19), 1992-1997, 2015 | 104 | 2015 |
The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5 Q Xia, A Chesi, E Manduchi, BT Johnston, S Lu, ME Leonard, UW Parlin, ... Diabetologia 59, 2360-2368, 2016 | 85 | 2016 |
A dementia-associated risk variant near TMEM106B alters chromatin architecture and gene expression MD Gallagher, M Posavi, P Huang, TL Unger, Y Berlyand, AL Gruenewald, ... The American Journal of Human Genetics 101 (5), 643-663, 2017 | 84 | 2017 |
The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression P Huang, SA Peslak, X Lan, E Khandros, JA Yano, M Sharma, CA Keller, ... Blood 135 (24), 2121-2132, 2020 | 57 | 2020 |
Alteration of genome folding via contact domain boundary insertion D Zhang, P Huang, M Sharma, CA Keller, B Giardine, H Zhang, ... Nature genetics 52 (10), 1076-1087, 2020 | 42 | 2020 |
Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression SK Topfer, R Feng, P Huang, LC Ly, GE Martyn, GA Blobel, MJ Weiss, ... Blood, The Journal of the American Society of Hematology 139 (14), 2107-2118, 2022 | 41 | 2022 |
Gfi1. 1 regulates hematopoietic lineage differentiation during zebrafish embryogenesis W Wei, L Wen, P Huang, Z Zhang, Y Chen, A Xiao, H Huang, Z Zhu, ... Cell research 18 (6), 677-685, 2008 | 40 | 2008 |
Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts E Khandros, P Huang, SA Peslak, M Sharma, O Abdulmalik, BM Giardine, ... Blood 135 (22), 1957-1968, 2020 | 35 | 2020 |