Multivalent control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme. M Nakanishi, JL Goldstein, MS Brown Journal of Biological Chemistry 263 (18), 8929-8937, 1988 | 417 | 1988 |
Protein transduction domain of HIV-1 Tat protein promotes efficient delivery of DNA into mammalian cells A Eguchi, T Akuta, H Okuyama, T Senda, H Yokoi, H Inokuchi, S Fujita, ... Journal of Biological Chemistry 276 (28), 26204-26210, 2001 | 408 | 2001 |
Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming K Nishimura, M Sano, M Ohtaka, B Furuta, Y Umemura, Y Nakajima, ... Journal of Biological Chemistry 286 (6), 4760-4771, 2011 | 371 | 2011 |
Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation T Nishimura, S Kaneko, A Kawana-Tachikawa, Y Tajima, H Goto, D Zhu, ... Cell stem cell 12 (1), 114-126, 2013 | 370 | 2013 |
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells N Takayama, S Nishimura, S Nakamura, T Shimizu, R Ohnishi, H Endo, ... Journal of Experimental Medicine 207 (13), 2817-2830, 2010 | 362 | 2010 |
Initiation of Sendai virus multiplication from transfected cDNA or RNA with negative or positive sense A Kato, Y Sakai, T Shioda, T Kondo, M Nakanishi, Y Nagai Genes to Cells 1 (6), 569-579, 1996 | 342 | 1996 |
Genetic variability overrides the impact of parental cell type and determines iPSC differentiation potential A Kyttälä, R Moraghebi, C Valensisi, J Kettunen, C Andrus, ... Stem cell reports 6 (2), 200-212, 2016 | 215 | 2016 |
Expression of hepatitis B virus surface antigen in adult rat liver. Co-introduction of DNA and nuclear protein by a simplified liposome method K Kato, M Nakanishi, Y Kaneda, T Uchida, Y Okada Journal of Biological Chemistry 266 (6), 3361-3364, 1991 | 211 | 1991 |
C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced … R Dafinca, J Scaber, N Ababneh, T Lalic, G Weir, H Christian, J Vowles, ... Stem cells 34 (8), 2063-2078, 2016 | 205 | 2016 |
Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins T Nakanishi, J Kunisawa, A Hayashi, Y Tsutsumi, K Kubo, S Nakagawa, ... Journal of controlled release 61 (1-2), 233-240, 1999 | 192 | 1999 |
Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes K Takayama, Y Morisaki, S Kuno, Y Nagamoto, K Harada, N Furukawa, ... Proceedings of the National Academy of Sciences 111 (47), 16772-16777, 2014 | 187 | 2014 |
Development of Sendai virus vectors and their potential applications in gene therapy and regenerative medicine M Nakanishi, M Otsu Current gene therapy 12 (5), 410-416, 2012 | 139 | 2012 |
Effect of asymmetric terminal structures of short RNA duplexes on the RNA interference activity and strand selection M Sano, M Sierant, M Miyagishi, M Nakanishi, Y Takagi, S Sutou Nucleic acids research 36 (18), 5812-5821, 2008 | 136 | 2008 |
Efficient introduction of contents of liposomes into cells using HVJ (Sendai virus) M Nakanishi, T Uchida, H Sugawa, M Ishiura, Y Okada Experimental cell research 159 (2), 399-409, 1985 | 125 | 1985 |
Efficient gene transfer into mammalian cells using fusogenic liposome H Mizuguchi, T Nakagawa, M Nakanishi, S Imazu, S Nakagawa, ... Biochemical and biophysical research communications 218 (1), 402-407, 1996 | 110 | 1996 |
Enhancing T cell receptor stability in rejuvenated iPSC-derived T cells improves their use in cancer immunotherapy A Minagawa, T Yoshikawa, M Yasukawa, A Hotta, M Kunitomo, S Iriguchi, ... Cell Stem Cell 23 (6), 850-858. e4, 2018 | 102 | 2018 |
Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics AE Handel, S Chintawar, T Lalic, E Whiteley, J Vowles, A Giustacchini, ... Human molecular genetics 25 (5), 989-1000, 2016 | 99 | 2016 |
Expansion of functional human mucosal-associated invariant T cells via reprogramming to pluripotency and redifferentiation H Wakao, K Yoshikiyo, U Koshimizu, T Furukawa, K Enomoto, ... Cell Stem Cell 12 (5), 546-558, 2013 | 96 | 2013 |
Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway T Nakanishi, A Hayashi, J Kunisawa, Y Tsutsumi, K Tanaka, ... European Journal of Immunology 30 (6), 1740-1747, 2000 | 88 | 2000 |
Application of fusogenic liposomes containing fragment A of diphtheria toxin to cancer therapy H Mizuguchi, M Nakanishi, T Nakanishi, T Nakagawa, S Nakagawa, ... British journal of cancer 73 (4), 472-476, 1996 | 86 | 1996 |