Release of chromatin protein HMGB1 by necrotic cells triggers inflammation P Scaffidi, T Misteli, ME Bianchi Nature 418 (6894), 191-195, 2002 | 5156 | 2002 |
Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion T Bonaldi, F Talamo, P Scaffidi, D Ferrera, A Porto, A Bachi, A Rubartelli, ... The EMBO journal, 2003 | 1541 | 2003 |
Lamin A-dependent nuclear defects in human aging P Scaffidi, T Misteli Science 312 (5776), 1059-1063, 2006 | 1395 | 2006 |
HMGB1 is an endogenous immune adjuvant released by necrotic cells P Rovere‐Querini, A Capobianco, P Scaffidi, B Valentinis, F Catalanotti, ... EMBO reports 5 (8), 825-830, 2004 | 761 | 2004 |
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome P Scaffidi, T Misteli Nature medicine 11 (4), 440-445, 2005 | 712 | 2005 |
The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells B Degryse, T Bonaldi, P Scaffidi, S Müller, M Resnati, F Sanvito, ... The Journal of cell biology 152 (6), 1197-1206, 2001 | 660 | 2001 |
The double life of HMGB1 chromatin protein: architectural factor and extracellular signal S Müller, P Scaffidi, B Degryse, T Bonaldi, L Ronfani, A Agresti, ... The EMBO journal, 2001 | 588 | 2001 |
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing P Scaffidi, T Misteli Nature cell biology 10 (4), 452-459, 2008 | 563 | 2008 |
Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins RD Phair, P Scaffidi, C Elbi, J Vecerová, A Dey, K Ozato, DT Brown, ... Molecular and cellular biology, 2004 | 542 | 2004 |
Distinct structural and mechanical properties of the nuclear lamina in Hutchinson–Gilford progeria syndrome KN Dahl, P Scaffidi, MF Islam, AG Yodh, KL Wilson, T Misteli Proceedings of the National Academy of Sciences 103 (27), 10271-10276, 2006 | 437 | 2006 |
Epigenetics and cancer stem cells: unleashing, hijacking, and restricting cellular plasticity EN Wainwright, P Scaffidi Trends in cancer 3 (5), 372-386, 2017 | 329 | 2017 |
Target-specific precision of CRISPR-mediated genome editing AM Chakrabarti, T Henser-Brownhill, J Monserrat, AR Poetsch, ... Molecular cell 73 (4), 699-713. e6, 2019 | 263 | 2019 |
The linker histone H1. 0 generates epigenetic and functional intratumor heterogeneity CM Torres, A Biran, MJ Burney, H Patel, T Henser-Brownhill, AHS Cohen, ... Science 353 (6307), aaf1644, 2016 | 186 | 2016 |
Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes C Pallier, P Scaffidi, S Chopineau-Proust, A Agresti, P Nordmann, ... Molecular biology of the cell 14 (8), 3414-3426, 2003 | 163 | 2003 |
In vitro generation of human cells with cancer stem cell properties P Scaffidi, T Misteli Nature cell biology 13 (9), 1051-1061, 2011 | 153 | 2011 |
Spatially precise DNA bending is an essential activity of the sox2 transcription factor P Scaffidi, ME Bianchi Journal of Biological Chemistry 276 (50), 47296-47302, 2001 | 153 | 2001 |
GR and HMGB1 interact only within chromatin and influence each other’s residence time A Agresti, P Scaffidi, A Riva, VR Caiolfa, ME Bianchi Molecular cell 18 (1), 109-121, 2005 | 133 | 2005 |
The cell nucleus and aging: tantalizing clues and hopeful promises P Scaffidi, L Gordon, T Misteli PLoS biology 3 (11), e395, 2005 | 81 | 2005 |
Transformation resistance in a premature aging disorder identifies a tumor-protective function of BRD4 P Fernandez, P Scaffidi, E Markert, JH Lee, S Rane, T Misteli Cell reports 9 (1), 248-260, 2014 | 73 | 2014 |
Histone H1 alterations in cancer P Scaffidi Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (3), 533-539, 2016 | 55 | 2016 |