James A. Lederer
James A. Lederer
Associate Professor, Brigham and Women's Hospital and Harvard Medical School
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
A network-based analysis of systemic inflammation in humans
SE Calvano, W Xiao, DR Richards, RM Felciano, HV Baker, RJ Cho, ...
Nature 437 (7061), 1032-1037, 2005
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
DA Rao, MF Gurish, JL Marshall, K Slowikowski, CY Fonseka, Y Liu, ...
Nature 542 (7639), 110-114, 2017
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
F Zhang, K Wei, K Slowikowski, CY Fonseka, DA Rao, S Kelly, ...
Nature immunology 20 (7), 928-942, 2019
Major injury leads to predominance of the T helper-2 lymphocyte phenotype and diminished interleukin-12 production associated with decreased resistance to infection
ST O'Sullivan, JA Lederer, AF Horgan, DHL Chin, JA Mannick, ...
Annals of surgery 222 (4), 482-492, 1995
Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity
E Shrock, E Fujimura, T Kula, RT Timms, IH Lee, Y Leng, ML Robinson, ...
Science 370 (6520), eabd4250, 2020
The immune cell landscape in kidneys of patients with lupus nephritis
A Arazi, DA Rao, CC Berthier, A Davidson, Y Liu, PJ Hoover, A Chicoine, ...
Nature immunology 20 (7), 902-914, 2019
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
F Mizoguchi, K Slowikowski, K Wei, JL Marshall, DA Rao, SK Chang, ...
Nature communications 9 (1), 789, 2018
The effects of injury on the adaptive immune response
JA Lederer, ML Rodrick, JA Mannick
Shock 11 (3), 153-159, 1999
Injury primes the innate immune system for enhanced Toll-like receptor reactivity
HM Paterson, TJ Murphy, EJ Purcell, O Shelley, SJ Kriynovich, E Lien, ...
The Journal of Immunology 171 (3), 1473-1483, 2003
The immunologic response to injury
JA Mannick, ML Rodrick, JA Lederer
Journal of the American College of Surgeons 193 (3), 237-244, 2001
Major injury induces increased production of interleukin-10 by cells of the immune system with a negative impact on resistance to infection
A Lyons, JL Kelly, ML Rodrick, JA Mannick, JA Lederer
Annals of surgery 226 (4), 450-460, 1997
Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule
I Gotsman, N Grabie, R Gupta, R Dacosta, M MacConmara, J Lederer, ...
Circulation 114 (19), 2047-2055, 2006
CD4+ CD25+ regulatory T cells control innate immune reactivity after injury
TJ Murphy, NN Choileain, Y Zang, JA Mannick, JA Lederer
The Journal of Immunology 174 (5), 2957-2963, 2005
Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene.
HA Young, P Ghosh, J Ye, J Lederer, A Lichtman, JR Gerard, L Penix, ...
Journal of immunology (Baltimore, Md.: 1950) 153 (8), 3603-3610, 1994
Impairment of the programmed cell death-1 pathway increases atherosclerotic lesion development and inflammation
D Bu, M Tarrio, E Maganto-Garcia, G Stavrakis, G Tajima, J Lederer, ...
Arteriosclerosis, thrombosis, and vascular biology 31 (5), 1100-1107, 2011
Targeting regulatory T cells in cancer
WL Byrne, KHG Mills, JA Lederer, GC O'Sullivan
Cancer research 71 (22), 6915-6920, 2011
Trauma equals danger—damage control by the immune system
VM Stoecklein, A Osuka, JA Lederer
Journal of leukocyte biology 92 (3), 539-551, 2012
Cytokine transcriptional events during helper T cell subset differentiation.
JA Lederer, VL Perez, L DesRoches, SM Kim, AK Abbas, AH Lichtman
The Journal of experimental medicine 184 (2), 397-406, 1996
Stability of Th1 and Th2 populations
VL Perez, JA Lederer, AH Lichtman, AK Abbas
International immunology 7 (5), 869-875, 1995
PD-1hiCXCR5–T peripheral helper cells promote B cell responses in lupus via MAF and IL-21
AV Bocharnikov, J Keegan, VS Wacleche, Y Cao, CY Fonseka, G Wang, ...
JCI insight 4 (20), 2019
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