Paul Mischel
Paul Mischel
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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
IK Mellinghoff, MY Wang, I Vivanco, DA Haas-Kogan, S Zhu, EQ Dia, ...
New England Journal of Medicine 353 (19), 2012-2024, 2005
Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma
AT Parsa, JS Waldron, A Panner, CA Crane, IF Parney, JJ Barry, ...
Nature medicine 13 (1), 84-88, 2007
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma
R Beroukhim, G Getz, L Nghiemphu, J Barretina, T Hsueh, D Linhart, ...
Proceedings of the National Academy of Sciences 104 (50), 20007-20012, 2007
High-throughput oncogene mutation profiling in human cancer
RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ...
Nature genetics 39 (3), 347-351, 2007
Gene expression profiling of gliomas strongly predicts survival
WA Freije, FE Castro-Vargas, Z Fang, S Horvath, T Cloughesy, LM Liau, ...
Cancer research 64 (18), 6503-6510, 2004
Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target
S Horvath, B Zhang, M Carlson, KV Lu, S Zhu, RM Felciano, MF Laurance, ...
Proceedings of the National Academy of Sciences 103 (46), 17402-17407, 2006
Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma
TF Cloughesy, K Yoshimoto, P Nghiemphu, K Brown, J Dang, S Zhu, ...
PLoS medicine 5 (1), e8, 2008
Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment
LM Liau, RM Prins, SM Kiertscher, SK Odesa, TJ Kremen, AJ Giovannone, ...
Clinical Cancer Research 11 (15), 5515-5525, 2005
Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity
KM Turner, V Deshpande, D Beyter, T Koga, J Rusert, C Lee, B Li, ...
Nature 543 (7643), 122-125, 2017
LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin
DB Shackelford, E Abt, L Gerken, DS Vasquez, A Seki, M Leblanc, L Wei, ...
Cancer cell 23 (2), 143-158, 2013
Glioblastoma: from molecular pathology to targeted treatment
TF Cloughesy, WK Cavenee, PS Mischel
Annual review of pathology: mechanisms of disease 9, 1-25, 2014
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA
DA Nathanson, B Gini, J Mottahedeh, K Visnyei, T Koga, G Gomez, ...
Science 343 (6166), 72-76, 2014
Analysis of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma patients in vivo
G Choe, S Horvath, TF Cloughesy, K Crosby, D Seligson, A Palotie, ...
Cancer research 63 (11), 2742-2746, 2003
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme
A Lai, A Tran, PL Nghiemphu, WB Pope, OE Solis, M Selch, E Filka, ...
Journal of clinical oncology 29 (2), 142, 2011
Imaging proliferation in brain tumors with 18F-FLT PET: comparison with 18F-FDG
W Chen, T Cloughesy, N Kamdar, N Satyamurthy, M Bergsneider, L Liau, ...
Journal of Nuclear Medicine 46 (6), 945-952, 2005
Metabolic state of glioma stem cells and nontumorigenic cells
E Vlashi, C Lagadec, L Vergnes, T Matsutani, K Masui, M Poulou, ...
Proceedings of the National Academy of Sciences 108 (38), 16062-16067, 2011
Cerebral cortical dysplasia associated with pediatric epilepsy. Review of neuropathologic features and proposal for a grading system
PS Mischel, LP Nguyen, HV Vinters
Journal of Neuropathology & Experimental Neurology 54 (2), 137-153, 1995
Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin
A Lai, S Kharbanda, WB Pope, A Tran, OE Solis, F Peale, WF Forrest, ...
Journal of clinical oncology 29 (34), 4482, 2011
Single-cell analysis tools for drug discovery and development
JR Heath, A Ribas, PS Mischel
Nature reviews Drug discovery 15 (3), 204-216, 2016
MR imaging correlates of survival in patients with high-grade gliomas
WB Pope, J Sayre, A Perlina, JP Villablanca, PS Mischel, TF Cloughesy
American Journal of Neuroradiology 26 (10), 2466-2474, 2005
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