Sequence saturation mutagenesis (SeSaM): a novel method for directed evolution TS Wong, KL Tee, B Hauer, U Schwaneberg Nucleic Acids Research 32 (3), e26-e26, 2004 | 289 | 2004 |
Laboratory evolution of cytochrome P450 BM‐3 monooxygenase for organic cosolvents T Seng Wong, FH Arnold, U Schwaneberg Biotechnology and bioengineering 85 (3), 351-358, 2004 | 258 | 2004 |
A statistical analysis of random mutagenesis methods used for directed protein evolution TS Wong, D Roccatano, M Zacharias, U Schwaneberg Journal of molecular biology 355 (4), 858-871, 2006 | 208 | 2006 |
The diversity challenge in directed protein evolution TS Wong, D Zhurina, U Schwaneberg Combinatorial chemistry & high throughput screening 9 (4), 271-288, 2006 | 196 | 2006 |
Protein engineering in bioelectrocatalysis TS Wong, U Schwaneberg Current Opinion in Biotechnology 14 (6), 590-596, 2003 | 167 | 2003 |
Carbon dioxide capture and utilization using biological systems: opportunities and challenges P Jajesniak, H Ali, TS Wong J Bioprocess Biotech 4 (3), 1-15, 2014 | 137 | 2014 |
Polishing the craft of genetic diversity creation in directed evolution KL Tee, TS Wong Biotechnology advances 31 (8), 1707-1721, 2013 | 135 | 2013 |
Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53 TS Wong, S Rajagopalan, SM Freund, TJ Rutherford, A Andreeva, ... Nucleic acids research 37 (20), 6765-6783, 2009 | 109 | 2009 |
Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53 TS Wong, S Rajagopalan, FM Townsley, SM Freund, M Petrovich, ... Nucleic acids research 37 (2), 568-581, 2009 | 109 | 2009 |
Steering directed protein evolution: strategies to manage combinatorial complexity of mutant libraries TS Wong, D Roccatano, U Schwaneberg Environmental microbiology 9 (11), 2645-2659, 2007 | 102 | 2007 |
Design and application of genetically-encoded malonyl-CoA biosensors for metabolic engineering of microbial cell factories AO Johnson, M Gonzalez-Villanueva, L Wong, A Steinbüchel, KL Tee, ... Metabolic engineering 44, 253-264, 2017 | 100 | 2017 |
The accessory subunit of mitochondrial DNA polymerase γ determines the DNA content of mitochondrial nucleoids in human cultured cells M Di Re, H Sembongi, J He, A Reyes, T Yasukawa, P Martinsson, ... Nucleic acids research 37 (17), 5701-5713, 2009 | 87 | 2009 |
Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds TS Wong, N Wu, D Roccatano, M Zacharias, U Schwaneberg Journal of biomolecular screening 10 (3), 246-252, 2005 | 82 | 2005 |
Understanding a mechanism of organic cosolvent inactivation in heme monooxygenase P450 BM-3 J Kuper, TS Wong, D Roccatano, M Wilmanns, U Schwaneberg Journal of the American Chemical Society 129 (18), 5786-5787, 2007 | 68 | 2007 |
Transversion-enriched sequence saturation mutagenesis (SeSaM-Tv+): a random mutagenesis method with consecutive nucleotide exchanges that complements the bias of error-prone PCR. TS Wong, D Roccatano, D Loakes, KL Tee, A Schenk, B Hauer, ... Biotechnology journal 3 (1), 74-82, 2008 | 60 | 2008 |
An Engineered Constitutive Promoter Set with Broad Activity Range for Cupriavidus necator H16 AO Johnson, M Gonzalez-Villanueva, KL Tee, TS Wong ACS synthetic biology 7 (8), 1918-1928, 2018 | 46 | 2018 |
Production of Trimeric SARS‐CoV‐2 Spike Protein by CHO Cells for Serological COVID‐19 Testing YB Johari, SRP Jaffé, JM Scarrott, AO Johnson, T Mozzanino, TH Pohle, ... Biotechnology and bioengineering, 2020 | 44 | 2020 |
Sequence saturation mutagenesis with tunable mutation frequencies TS Wong, KL Tee, B Hauer, U Schwaneberg Analytical biochemistry 341 (1), 187-189, 2005 | 42 | 2005 |
Challenges of the genetic code for exploring sequence space in directed protein evolution TS Wong, TS Wong, D Roccatano*, U Schwaneberg Biocatalysis and biotransformation 25 (2-4), 229-241, 2007 | 41 | 2007 |
Are transversion mutations better? A Mutagenesis Assistant Program analysis on P450 BM‐3 heme domain TS Wong, D Roccatano, U Schwaneberg Biotechnology journal 2 (1), 133-142, 2007 | 41 | 2007 |