| Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche T Sato, RG Vries, HJ Snippert, M Van De Wetering, N Barker, DE Stange, ... Nature 459 (7244), 262-265, 2009 | 7155 | 2009 |
| Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts T Sato, JH Van Es, HJ Snippert, DE Stange, RG Vries, M Van Den Born, ... Nature 469 (7330), 415-418, 2011 | 2820 | 2011 |
| Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells HJ Snippert, LG Van Der Flier, T Sato, JH Van Es, M Van Den Born, ... Cell 143 (1), 134-144, 2010 | 2084 | 2010 |
| Lgr5+ ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro N Barker, M Huch, P Kujala, M van de Wetering, HJ Snippert, JH van Es, ... Cell stem cell 6 (1), 25-36, 2010 | 1785 | 2010 |
| Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas AG Schepers, HJ Snippert, DE Stange, M van den Born, JH van Es, ... Science 337 (6095), 730-735, 2012 | 1267 | 2012 |
| Lgr5 marks cycling, yet long-lived, hair follicle stem cells V Jaks, N Barker, M Kasper, JH Van Es, HJ Snippert, H Clevers, ... Nature genetics 40 (11), 1291-1299, 2008 | 1129 | 2008 |
| Sequential cancer mutations in cultured human intestinal stem cells J Drost, RH Van Jaarsveld, B Ponsioen, C Zimberlin, R Van Boxtel, ... Nature 521 (7550), 43-47, 2015 | 1099 | 2015 |
| Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin HJ Snippert, A Haegebarth, M Kasper, V Jaks, JH van Es, N Barker, ... Science 327 (5971), 1385-1389, 2010 | 897 | 2010 |
| An organoid platform for ovarian cancer captures intra-and interpatient heterogeneity O Kopper, CJ De Witte, K Lõhmussaar, JE Valle-Inclan, N Hami, L Kester, ... Nature medicine 25 (5), 838-849, 2019 | 678 | 2019 |
| Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging L Ritsma, SIJ Ellenbroek, A Zomer, HJ Snippert, FJ De Sauvage, ... Nature 507 (7492), 362-365, 2014 | 532 | 2014 |
| Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation S Bardehle, M Krüger, F Buggenthin, J Schwausch, J Ninkovic, H Clevers, ... Nature neuroscience 16 (5), 580-586, 2013 | 485 | 2013 |
| Interplay between metabolic identities in the intestinal crypt supports stem cell function MJ Rodríguez-Colman, M Schewe, M Meerlo, E Stigter, J Gerrits, ... Nature 543 (7645), 424-427, 2017 | 484 | 2017 |
| High-resolution 3D imaging of fixed and cleared organoids JF Dekkers, M Alieva, LM Wellens, HCR Ariese, PR Jamieson, AM Vonk, ... Nature protocols 14 (6), 1756-1771, 2019 | 428 | 2019 |
| Microbiota controls the homeostasis of glial cells in the gut lamina propria PS Kabouridis, R Lasrado, S McCallum, SH Chng, HJ Snippert, H Clevers, ... Neuron 85 (2), 289-295, 2015 | 365 | 2015 |
| Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion HJ Snippert, AG Schepers, JH Van Es, BD Simons, H Clevers EMBO reports 15 (1), 62-69, 2014 | 271 | 2014 |
| Lgr5+ ve stem/progenitor cells contribute to nephron formation during kidney development N Barker, MB Rookmaaker, P Kujala, A Ng, M Leushacke, H Snippert, ... Cell reports 2 (3), 540-552, 2012 | 261 | 2012 |
| Stem cell dynamics in homeostasis and cancer of the intestine L Vermeulen, HJ Snippert Nature Reviews Cancer 14 (7), 468-480, 2014 | 260 | 2014 |
| Plasticity of Lgr5-negative cancer cells drives metastasis in colorectal cancer A Fumagalli, KC Oost, L Kester, J Morgner, L Bornes, L Bruens, ... Cell stem cell 26 (4), 569-578. e7, 2020 | 258 | 2020 |
| Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine HJ Snippert, JH van Es, M van den Born, H Begthel, DE Stange, N Barker, ... Gastroenterology 136 (7), 2187-2194. e1, 2009 | 251 | 2009 |
| Tracking adult stem cells HJ Snippert, H Clevers EMBO reports 12 (2), 113-122, 2011 | 250 | 2011 |
Hans CleversHubrecht Institute - UtrechtBestätigte E-Mail-Adresse bei hubrecht.eu
