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Liang Wu
Liang Wu
DSM Biotechnology Center
Bestätigte E-Mail-Adresse bei dsm.com
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Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards
L Wu, MR Mashego, JC van Dam, AM Proell, JL Vinke, C Ras, ...
Analytical biochemistry 336 (2), 164-171, 2005
4682005
MIRACLE: mass isotopomer ratio analysis of U‐13C‐labeled extracts. A new method for accurate quantification of changes in concentrations of intracellular …
MR Mashego, L Wu, JC Van Dam, C Ras, JL Vinke, WA Van Winden, ...
Biotechnology and bioengineering 85 (6), 620-628, 2004
3192004
The sequence of a 1.8-Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways
MH Medema, A Trefzer, A Kovalchuk, M Van Den Berg, U Müller, ...
Genome Biology and Evolution 2, 212-224, 2010
2412010
Replacement of the Saccharomyces cerevisiae acetyl-CoA synthetases by alternative pathways for cytosolic acetyl-CoA synthesis
BU Kozak, HM van Rossum, KR Benjamin, L Wu, JMG Daran, JT Pronk, ...
Metabolic engineering 21, 46-59, 2014
1262014
Metabolic engineering toward sustainable production of nylon-6
SCHJ Turk, WP Kloosterman, DK Ninaber, KPAM Kolen, J Knutova, E Suir, ...
ACS synthetic biology 5 (1), 65-73, 2016
1122016
Analysis of in vivo kinetics of glycolysis in aerobic Saccharomyces cerevisiae by application of glucose and ethanol pulses
D Visser, GA van Zuylen, JC van Dam, MR Eman, A Pröll, C Ras, L Wu, ...
Biotechnology and Bioengineering 88 (2), 157-167, 2004
1092004
Engineering acetyl coenzyme A supply: functional expression of a bacterial pyruvate dehydrogenase complex in the cytosol of Saccharomyces cerevisiae
BU Kozak, HM van Rossum, MAH Luttik, M Akeroyd, KR Benjamin, L Wu, ...
MBio 5 (5), 10.1128/mbio. 01696-14, 2014
1052014
A new framework for the estimation of control parameters in metabolic pathways using lin‐log kinetics
L Wu, W Wang, WA Van Winden, WM Van Gulik, JJ Heijnen
European Journal of Biochemistry 271 (16), 3348-3359, 2004
952004
Short-Term Metabolome Dynamics and Carbon, Electron, and ATP Balances in Chemostat-Grown Saccharomyces cerevisiae CEN.PK 113-7D following a Glucose …
L Wu, J van Dam, D Schipper, MTAP Kresnowati, AM Proell, C Ras, ...
Applied and environmental microbiology 72 (5), 3566-3577, 2006
722006
Iterative algorithm-guided design of massive strain libraries, applied to itaconic acid production in yeast
EM Young, Z Zhao, BEM Gielesen, L Wu, DB Gordon, JA Roubos, ...
Metabolic engineering 48, 33-43, 2018
552018
Diterpene production
M Lehmann, J Trueheart, PZ Jens, L Wu, VM Boer, CMJ Sagt, M Kumar, ...
US Patent App. 14/373,571, 2015
492015
In vivo kinetics of primary metabolism in Saccharomyces cerevisiae studied through prolonged chemostat cultivation
L Wu, MR Mashego, AM Proell, JL Vinke, C Ras, J Van Dam, ...
Metabolic Engineering 8 (2), 160-171, 2006
442006
Determination of in vivo oxygen uptake and carbon dioxide evolution rates from off‐gas measurements under highly dynamic conditions
L Wu, HC Lange, WM Van Gulik, JJ Heijnen
Biotechnology and bioengineering 81 (4), 448-458, 2003
412003
Thermodynamics and economic feasibility of acetone production from syngas using the thermophilic production host Moorella thermoacetica
S Redl, S Sukumara, T Ploeger, L Wu, T Ølshøj Jensen, AT Nielsen, ...
Biotechnology for biofuels 10, 1-17, 2017
382017
Application of metabolome data in functional genomics: a conceptual strategy
L Wu, WA van Winden, WM van Gulik, JJ Heijnen
Metabolic Engineering 7 (4), 302-310, 2005
292005
Acetyl-coa producing enzymes in yeast
UM Müller, L Wu, LM Raamsdonk, AA Winkler
US Patent App. 12/670,050, 2010
272010
Reconstruction of the O2 uptake rate and CO2 evolution rate on a time scale of seconds
HHJ Bloemen, L Wu, WM Van Gulik, JJ Heijnen, MHG Verhaegen
AIChE journal 49 (7), 1895-1908, 2003
272003
Exploring Sequence Characteristics Related to High-Level Production of Secreted Proteins in Aspergillus niger
BA van den Berg, MJT Reinders, M Hulsman, L Wu, HJ Pel, JA Roubos, ...
Public Library of Science 7 (10), e45869, 2012
202012
Replacement of the initial steps of ethanol metabolism in Saccharomyces cerevisiae by ATP-independent acetylating acetaldehyde dehydrogenase
BU Kozak, HM van Rossum, MS Niemeijer, M van Dijk, K Benjamin, L Wu, ...
FEMS Yeast Research 16 (2), fow006, 2016
192016
Succinic acid production in a eukaryotic cell
R Verwaal, L Wu, RA Damveld, CMJ Sagt
WO2009065778, 2009
172009
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