Transient protein-protein interactions: structural, functional, and network properties JR Perkins, I Diboun, BH Dessailly, JG Lees, C Orengo Structure 18 (10), 1233-1243, 2010 | 624 | 2010 |
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures I Sillitoe, AL Cuff, BH Dessailly, NL Dawson, N Furnham, D Lee, JG Lees, ... Nucleic acids research 41 (D1), D490-D498, 2012 | 276 | 2012 |
Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes RA Studer, BH Dessailly, CA Orengo Biochemical journal 449 (3), 581-594, 2013 | 244 | 2013 |
Exploring the structure and function paradigm OC Redfern, B Dessailly, CA Orengo Current opinion in structural biology 18 (3), 394-402, 2008 | 159 | 2008 |
PSI-2: structural genomics to cover protein domain family space BH Dessailly, R Nair, L Jaroszewski, JE Fajardo, A Kouranov, D Lee, ... Structure 17 (6), 869-881, 2009 | 153 | 2009 |
Gene3D: a domain-based resource for comparative genomics, functional annotation and protein network analysis J Lees, C Yeats, J Perkins, I Sillitoe, R Rentzsch, BH Dessailly, C Orengo Nucleic acids research 40 (D1), D465-D471, 2012 | 111 | 2012 |
LigASite—a database of biologically relevant binding sites in proteins with known apo -structures BH Dessailly, MF Lensink, CA Orengo, SJ Wodak Nucleic acids research 36 (suppl_1), D667-D673, 2007 | 107 | 2007 |
Gene3D: Multi-domain annotations for protein sequence and comparative genome analysis JG Lees, D Lee, RA Studer, NL Dawson, I Sillitoe, S Das, C Yeats, ... Nucleic acids research 42 (D1), D240-D245, 2014 | 66 | 2014 |
FLORA: a novel method to predict protein function from structure in diverse superfamilies OC Redfern, BH Dessailly, TJ Dallman, I Sillitoe, CA Orengo PLoS computational biology 5 (8), e1000485, 2009 | 53 | 2009 |
Benchmarking network propagation methods for disease gene identification S Picart-Armada, SJ Barrett, DR Willé, A Perera-Lluna, A Gutteridge, ... PLoS computational biology 15 (9), e1007276, 2019 | 49 | 2019 |
Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering C Yu, AFP Sonnen, R George, BH Dessailly, LJ Stagg, EJ Evans, ... Journal of biological chemistry 286 (8), 6685-6696, 2011 | 49 | 2011 |
The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant CK Tang, T Aoshi, N Jounai, J Ito, K Ohata, K Kobiyama, BH Dessailly, ... PloS one 8 (3), e60038, 2013 | 41 | 2013 |
Exploiting structural classifications for function prediction: towards a domain grammar for protein function BH Dessailly, OC Redfern, A Cuff, CA Orengo Current opinion in structural biology 19 (3), 349-356, 2009 | 38 | 2009 |
Functional site plasticity in domain superfamilies BH Dessailly, NL Dawson, K Mizuguchi, CA Orengo Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (5), 874-889, 2013 | 32 | 2013 |
Evolutionary history of the TBP-domain superfamily B Brindefalk, BH Dessailly, C Yeats, C Orengo, F Werner, AM Poole Nucleic acids research 41 (5), 2832-2845, 2013 | 31 | 2013 |
Detailed analysis of function divergence in a large and diverse domain superfamily: toward a refined protocol of function classification BH Dessailly, OC Redfern, AL Cuff, CA Orengo Structure 18 (11), 1522-1535, 2010 | 31 | 2010 |
Relating destabilizing regions to known functional sites in proteins BH Dessailly, MF Lensink, SJ Wodak BMC bioinformatics 8, 1-22, 2007 | 30 | 2007 |
Integrated pathway clusters with coherent biological themes for target prioritisation YA Chen, LP Tripathi, BH Dessailly, J Nystroem-Persson, S Ahmad, ... PloS one 9 (6), e99030, 2014 | 26 | 2014 |
Function diversity within folds and superfamilies BH Dessailly, NL Dawson, S Das, CA Orengo From protein structure to function with bioinformatics, 295-325, 2017 | 10 | 2017 |
The evolution of protein functions and networks: a family-centric approach BH Dessailly, AJ Reid, C Yeats, JG Lees, A Cuff, CA Orengo Biochemical Society Transactions 37 (4), 745-750, 2009 | 5 | 2009 |