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Alfredo De Biasio
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Structure of the processive human Pol δ holoenzyme
C Lancey, M Tehseen, VS Raducanu, F Rashid, N Merino, TJ Ragan, ...
Nature communications 11 (1), 1109, 2020
1162020
Proliferating cell nuclear antigen structure and interactions: too many partners for one dancer?
A De Biasio, FJ Blanco
Advances in protein chemistry and structural biology 91, 1-36, 2013
962013
Structural basis of human PCNA sliding on DNA
M De March, N Merino, S Barrera-Vilarmau, R Crehuet, S Onesti, ...
Nature communications 8 (1), 13935, 2017
832017
Structure of p15PAF–PCNA complex and implications for clamp sliding during DNA replication and repair
A De Biasio, AI De Opakua, GB Mortuza, R Molina, TN Cordeiro, ...
Nature communications 6 (1), 6439, 2015
782015
The intracellular region of Notch ligands: does the tail make the difference?
A Pintar, A De Biasio, M Popovic, N Ivanova
Biology direct 2, 1-13, 2007
782007
p15PAF is an intrinsically disordered protein with nonrandom structural preferences at sites of interaction with other proteins
A De Biasio, AI De Opakua, TN Cordeiro, M Villate, N Merino, N Sibille, ...
Biophysical journal 106 (4), 865-874, 2014
582014
N-terminal truncation of antiapoptotic MCL1, but not G2/M-induced phosphorylation, is associated with stabilization and abundant expression in tumor cells
A De Biasio, JA Vrana, P Zhou, L Qian, CK Bieszczad, KE Braley, ...
Journal of Biological Chemistry 282 (33), 23919-23936, 2007
512007
Thr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancer
SK Nifoussi, JA Vrana, AM Domina, A De Biasio, J Gui, MA Gregory, ...
Public Library of Science 7 (10), e47060, 2012
482012
Prevalence of intrinsic disorder in the intracellular region of human single-pass type I proteins: the case of the notch ligand Delta-4
A De Biasio, C Guarnaccia, M Popovic, VN Uversky, A Pintar, S Pongor
Journal of proteome research 7 (6), 2496-2506, 2008
452008
Mode of interaction between β2GPI and lipoprotein receptors suggests mutually exclusive binding of β2GPI to the receptors and anionic phospholipids
CJ Lee, A De Biasio, N Beglova
Structure 18 (3), 366-376, 2010
422010
Disentangling polydispersity in the PCNA−p15PAF complex, a disordered, transient and multivalent macromolecular assembly
TN Cordeiro, P Chen, A De Biasio, N Sibille, FJ Blanco, JS Hub, ...
Nucleic acids research 45 (3), 1501-1515, 2017
372017
Reduced stability and increased dynamics in the human proliferating cell nuclear antigen (PCNA) relative to the yeast homolog
A De Biasio, R Sánchez, J Prieto, M Villate, R Campos-Olivas, FJ Blanco
PloS one 6 (2), e16600, 2011
372011
Proliferating cell nuclear antigen (PCNA) interactions in solution studied by NMR
A De Biasio, R Campos-Olivas, R Sánchez, JP López-Alonso, ...
PLoS One 7 (11), e48390, 2012
342012
A novel dimeric inhibitor targeting Beta2GPI in Beta2GPI/antibody complexes implicated in antiphospholipid syndrome
A Kolyada, CJ Lee, A De Biasio, N Beglova
PLoS One 5 (12), e15345, 2010
332010
The intracellular region of the Notch ligand Jagged‐1 gains partial structure upon binding to synthetic membranes
M Popovic, A De Biasio, A Pintar, S Pongor
The FEBS Journal 274 (20), 5325-5336, 2007
322007
The dark side of the ring: role of the DNA sliding surface of PCNA
M De March, A De Biasio
Critical reviews in biochemistry and molecular biology 52 (6), 663-673, 2017
262017
Cryo-EM structure of human Pol κ bound to DNA and mono-ubiquitylated PCNA
C Lancey, M Tehseen, S Bakshi, M Percival, M Takahashi, MA Sobhy, ...
Nature Communications 12 (1), 6095, 2021
252021
p15PAF binding to PCNA modulates the DNA sliding surface
M De March, S Barrera-Vilarmau, E Crespan, E Mentegari, N Merino, ...
Nucleic acids research 46 (18), 9816-9828, 2018
222018
Double Monoubiquitination Modifies the Molecular Recognition Properties of p15PAF Promoting Binding to the Reader Module of Dnmt1
A González-Magaña, AI De Opakua, N Merino, H Monteiro, T Diercks, ...
ACS chemical biology 14 (10), 2315-2326, 2019
192019
The p12 subunit of human polymerase δ uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA)
A Gonzalez-Magaña, AI De Opakua, M Romano-Moreno, ...
Journal of biological chemistry 294 (11), 3947-3956, 2019
172019
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