Decoding myofibroblast origins in human kidney fibrosis C Kuppe, MM Ibrahim, J Kranz, X Zhang, S Ziegler, J Perales-Patón, ... Nature 589 (7841), 281-286, 2021 | 526 | 2021 |
Mutant calreticulin requires both its mutant C-terminus and the thrombopoietin receptor for oncogenic transformation S Elf, NS Abdelfattah, E Chen, J Perales-Patón, EA Rosen, A Ko, ... Cancer discovery 6 (4), 368-381, 2016 | 292* | 2016 |
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data CH Holland, J Tanevski, J Perales-Patón, J Gleixner, MP Kumar, E Mereu, ... Genome biology 21, 1-19, 2020 | 266 | 2020 |
The miR-146b-3p/PAX8/NIS regulatory circuit modulates the differentiation phenotype and function of thyroid cells during carcinogenesis G Riesco-Eizaguirre, L Wert-Lamas, J Perales-Paton, A Sastre-Perona, ... Cancer research 75 (19), 4119-4130, 2015 | 111 | 2015 |
Complete regression of advanced pancreatic ductal adenocarcinomas upon combined inhibition of EGFR and C-RAF MT Blasco, C Navas, G Martín-Serrano, O Graña-Castro, CG Lechuga, ... Cancer cell 35 (4), 573-587. e6, 2019 | 104 | 2019 |
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells LP Vu, C Prieto, EM Amin, S Chhangawala, A Krivtsov, MN Calvo-Vidal, ... Nature genetics 49 (6), 866-875, 2017 | 93 | 2017 |
PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data E Piñeiro-Yáñez, M Reboiro-Jato, G Gómez-López, J Perales-Patón, ... Genome medicine 10, 1-11, 2018 | 83 | 2018 |
MicroRNA deep-sequencing reveals master regulators of follicular and papillary thyroid tumors V Mancikova, E Castelblanco, E Pineiro-Yanez, J Perales-Paton, ... Modern Pathology 28 (6), 748-757, 2015 | 71 | 2015 |
Differential expression of microRNA miR-150-5p in IgA nephropathy as a potential mediator and marker of disease progression IZA Pawluczyk, A Didangelos, SJ Barbour, L Er, JU Becker, R Martin, ... Kidney international 99 (5), 1127-1139, 2021 | 52 | 2021 |
Discovery of new targets to control metastasis in pancreatic cancer by single-cell transcriptomics analysis of circulating tumor cells S Dimitrov-Markov, J Perales-Patón, B Bockorny, A Dopazo, M Muñoz, ... Molecular Cancer Therapeutics 19 (8), 1751-1760, 2020 | 39 | 2020 |
Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease Y Xu, C Kuppe, J Perales-Patón, S Hayat, J Kranz, AT Abdallah, J Nagai, ... Nature genetics 54 (11), 1690-1701, 2022 | 29 | 2022 |
Cross-regional homeostatic and reactive glial signatures in multiple sclerosis T Trobisch, A Zulji, NA Stevens, S Schwarz, S Wischnewski, M Öztürk, ... Acta neuropathologica 144 (5), 987-1003, 2022 | 24 | 2022 |
Multilayer OMIC Data in Medullary Thyroid Carcinoma Identifies the STAT3 Pathway as a Potential Therapeutic Target in RETM918T Tumors V Mancikova, C Montero-Conde, J Perales-Paton, A Fernandez, ... Clinical Cancer Research 23 (5), 1334-1345, 2017 | 24 | 2017 |
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling K van Kuijk, JAF Demandt, J Perales-Patón, TL Theelen, C Kuppe, ... Cardiovascular Research 118 (5), 1232-1246, 2022 | 16 | 2022 |
Pancreas cancer precision treatment using avatar mice from a bioinformatics perspective J Perales-Patón, E Piñeiro-Yañez, H Tejero, PP López-Casas, M Hidalgo, ... Public health genomics 20 (2), 81-91, 2017 | 13 | 2017 |
Experimental and computational technologies to dissect the kidney at the single-cell level C Kuppe, J Perales-Patón, J Saez-Rodriguez, R Kramann Nephrology Dialysis Transplantation 37 (4), 628-637, 2022 | 11 | 2022 |
Sex-specific differences in cytokine signaling pathways in circulating monocytes of cardiovascular disease patients C Lu, MMPC Donners, J Karel, H de Boer, AJ van Zonneveld, ... Atherosclerosis 384, 117123, 2023 | 10 | 2023 |
Dianhydrogalactitol overcomes multiple temozolomide resistance mechanisms in glioblastoma M Jiménez-Alcázar, Á Curiel-García, P Nogales, J Perales-Patón, ... Molecular cancer therapeutics 20 (6), 1029-1038, 2021 | 10 | 2021 |
vulcanSpot: a tool to prioritize therapeutic vulnerabilities in cancer J Perales-Patón, T Di Domenico, C Fustero-Torre, E Piñeiro-Yáñez, ... Bioinformatics 35 (22), 4846-4848, 2019 | 10 | 2019 |
Partial inhibition of the 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase-3 (PFKFB3) enzyme in myeloid cells does not affect atherosclerosis RJHA Tillie, J De Bruijn, J Perales-Patón, L Temmerman, Y Ghosheh, ... Frontiers in cell and developmental biology 9, 695684, 2021 | 9 | 2021 |