Ulrich Zachariae
Ulrich Zachariae
Professor of Molecular Biophysics, University of Dundee
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Zitiert von
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Ion permeation in K+ channels occurs by direct Coulomb knock-on
DA Köpfer, C Song, T Gruene, GM Sheldrick, U Zachariae, BL de Groot
Science 346 (6207), 352-355, 2014
Computational electrophysiology: the molecular dynamics of ion channel permeation and selectivity in atomistic detail
C Kutzner, H Grubmüller, BL De Groot, U Zachariae
Biophysical journal 101 (4), 809-817, 2011
Direct knock-on of desolvated ions governs strict ion selectivity in K+ channels
W Kopec, DA Köpfer, ON Vickery, AS Bondarenko, TLC Jansen, ...
Nature chemistry 10 (8), 813-820, 2018
Structure of the MacAB–TolC ABC-type tripartite multidrug efflux pump
AWP Fitzpatrick, S Llabrés, A Neuberger, JN Blaza, X Bai, U Okada, ...
Nature microbiology 2 (7), 1-8, 2017
Crystal structure and functional mechanism of a human antimicrobial membrane channel
C Song, C Weichbrodt, ES Salnikov, M Dynowski, BO Forsberg, ...
Proceedings of the National Academy of Sciences 110 (12), 4586-4591, 2013
Mechanisms of anion conduction by coupled glutamate transporters
JP Machtens, D Kortzak, C Lansche, A Leinenweber, P Kilian, ...
Cell 160 (3), 542-553, 2015
β-Barrel mobility underlies closure of the voltage-dependent anion channel
U Zachariae, R Schneider, R Briones, Z Gattin, JP Demers, K Giller, ...
Structure 20 (9), 1540-1549, 2012
Functional dynamics in the voltage-dependent anion channel
S Villinger, R Briones, K Giller, U Zachariae, A Lange, BL de Groot, ...
Proceedings of the National Academy of Sciences 107 (52), 22546-22551, 2010
GPCRmd uncovers the dynamics of the 3D-GPCRome
I Rodríguez-Espigares, M Torrens-Fontanals, JKS Tiemann, ...
Nature Methods 17 (8), 777-787, 2020
Position of transmembrane helix 6 determines receptor G protein coupling specificity
AS Rose, M Elgeti, U Zachariae, H Grubmüller, KP Hofmann, ...
Journal of the American Chemical Society 136 (32), 11244-11247, 2014
Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7
RA Pumroy, S Ke, DJ Hart, U Zachariae, G Cingolani
Structure 23 (2), 374-384, 2015
Quantitative structural analysis of importin-β flexibility: paradigm for solenoid protein structures
JK Forwood, A Lange, U Zachariae, M Marfori, C Preast, H Grubmüller, ...
Structure 18 (9), 1171-1183, 2010
Structural basis for cooperativity of CRM1 export complex formation
T Monecke, D Haselbach, B Voß, A Russek, P Neumann, E Thomson, ...
Proceedings of the National Academy of Sciences 110 (3), 960-965, 2013
An unusual hydrophobic core confers extreme flexibility to HEAT repeat proteins
C Kappel, U Zachariae, N Dölker, H Grubmüller
Biophysical journal 99 (5), 1596-1603, 2010
Intracellular transfer of Na+ in an active-state G-protein-coupled receptor
ON Vickery, CA Carvalheda, SA Zaidi, AV Pisliakov, V Katritch, ...
Structure 26 (1), 171-180. e2, 2018
Interfacial self-assembly of a bacterial hydrophobin
KM Bromley, RJ Morris, L Hobley, G Brandani, RMC Gillespie, ...
Proceedings of the National Academy of Sciences 112 (17), 5419-5424, 2015
Insights into the function of ion channels by computational electrophysiology simulations
C Kutzner, DA Köpfer, JP Machtens, BL De Groot, C Song, U Zachariae
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (7), 1741-1752, 2016
Toward a consensus model of the HERG potassium channel
A Stary, SJ Wacker, L Boukharta, U Zachariae, Y Karimi‐Nejad, J Åqvist, ...
ChemMedChem 5 (3), 455-467, 2010
Importin-β: structural and dynamic determinants of a molecular spring
U Zachariae, H Grubmüller
Structure 16 (6), 906-915, 2008
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers
U Zachariae, F Giordanetto, AG Leach
Journal of medicinal chemistry 52 (14), 4266-4276, 2009
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