Roman Yelensky
Roman Yelensky
CTO, Gritstone Oncology
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
GM Frampton, A Fichtenholtz, GA Otto, K Wang, SR Downing, J He, ...
Nature biotechnology 31 (11), 1023-1031, 2013
Efficiency and power in genetic association studies
PIW De Bakker, R Yelensky, I Pe'er, SB Gabriel, MJ Daly, D Altshuler
Nature genetics 37 (11), 1217-1223, 2005
Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial
EM Swisher, KK Lin, AM Oza, CL Scott, H Giordano, J Sun, GE Konecny, ...
The lancet oncology 18 (1), 75-87, 2017
Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
D Lipson, M Capelletti, R Yelensky, G Otto, A Parker, M Jarosz, JA Curran, ...
Nature medicine 18 (3), 382-384, 2012
Estimation of the multiple testing burden for genomewide association studies of nearly all common variants
I Pe'er, R Yelensky, D Altshuler, MJ Daly
Genetic Epidemiology: The Official Publication of the International Genetic …, 2008
Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors
GM Frampton, SM Ali, M Rosenzweig, J Chmielecki, X Lu, TM Bauer, ...
Cancer discovery 5 (8), 850-859, 2015
Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor–positive breast cancer
R Jeselsohn, R Yelensky, G Buchwalter, G Frampton, F Meric-Bernstam, ...
Clinical cancer research 20 (7), 1757-1767, 2014
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas
T Wiesner, J He, R Yelensky, R Esteve-Puig, T Botton, I Yeh, D Lipson, ...
Nature communications 5 (1), 3116, 2014
Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets
JM Balko, JM Giltnane, K Wang, LJ Schwarz, CD Young, RS Cook, ...
Cancer discovery 4 (2), 232-245, 2014
Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity
H Beltran, R Yelensky, GM Frampton, K Park, SR Downing, ...
European urology 63 (5), 920-926, 2013
RAS/MAPK activation is associated with reduced tumor-infiltrating lymphocytes in triple-negative breast cancer: therapeutic cooperation between MEK and PD-1/PD-L1 immune …
S Loi, S Dushyanthen, PA Beavis, R Salgado, C Denkert, P Savas, ...
Clinical Cancer Research 22 (6), 1499-1509, 2016
New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing
JS Ross, K Wang, L Gay, R Al-Rohil, JV Rand, DM Jones, HJ Lee, ...
The oncologist 19 (3), 235-242, 2014
Defects in DNA repair genes predict response to neoadjuvant cisplatin-based chemotherapy in muscle-invasive bladder cancer
ER Plimack, RL Dunbrack, TA Brennan, MD Andrake, Y Zhou, ...
European urology 68 (6), 959-967, 2015
D538G mutation in estrogen receptor-α: A novel mechanism for acquired endocrine resistance in breast cancer
K Merenbakh-Lamin, N Ben-Baruch, A Yeheskel, A Dvir, ...
Cancer research 73 (23), 6856-6864, 2013
Genome-wide discovery of transcriptional modules from DNA sequence and gene expression
E Segal, R Yelensky, D Koller
Bioinformatics-Oxford 19 (1), 273-282, 2003
Evaluating and improving power in whole-genome association studies using fixed marker sets
I Pe'er, PIW de Bakker, J Maller, R Yelensky, D Altshuler, MJ Daly
Nature genetics 38 (6), 663-667, 2006
Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms
R Rampal, J Ahn, O Abdel-Wahab, M Nahas, K Wang, D Lipson, GA Otto, ...
Proceedings of the National Academy of Sciences 111 (50), E5401-E5410, 2014
Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines
E Choy, R Yelensky, S Bonakdar, RM Plenge, R Saxena, PL De Jager, ...
PLoS genetics 4 (11), e1000287, 2008
Optimization of multigene analysis of tumor samples
D Lipson, GA Otto, AN Parker, PJ Stephens, SR Downing, M Jarosz, ...
US Patent 9,340,830, 2016
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting
J He, O Abdel-Wahab, MK Nahas, K Wang, RK Rampal, AM Intlekofer, ...
Blood, The Journal of the American Society of Hematology 127 (24), 3004-3014, 2016
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