Fitness costs of plasmids: a limit to plasmid transmission A San Millan, RC MacLean Microbiology spectrum 5 (5), 10.1128/microbiolspec. mtbp-0016-2017, 2017 | 475 | 2017 |
Evolution of plasmid-mediated antibiotic resistance in the clinical context A San Millan Trends in microbiology 26 (12), 978-985, 2018 | 428 | 2018 |
The evolution of antibiotic resistance RC MacLean, A San Millan Science 365 (6458), 1082-1083, 2019 | 369 | 2019 |
Beyond horizontal gene transfer: the role of plasmids in bacterial evolution J Rodríguez-Beltrán, J DelaFuente, R Leon-Sampedro, RC MacLean, ... Nature Reviews Microbiology 19 (6), 347-359, 2021 | 320 | 2021 |
Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids AS Millan, R Peña-Miller, M Toll-Riera, ZV Halbert, AR McLean, ... Nature communications 5 (1), 5208, 2014 | 276 | 2014 |
Multicopy plasmids potentiate the evolution of antibiotic resistance in bacteria A San Millan, JA Escudero, DR Gifford, D Mazel, RC MacLean Nature ecology & evolution 1 (1), 0010, 2016 | 200 | 2016 |
Positive epistasis between co-infecting plasmids promotes plasmid survival in bacterial populations A San Millan, K Heilbron, RC MacLean The ISME journal 8 (3), 601-612, 2014 | 196 | 2014 |
Interactions between horizontally acquired genes create a fitness cost in Pseudomonas aeruginosa A San Millan, M Toll-Riera, Q Qi, RC MacLean Nature communications 6 (1), 6845, 2015 | 184 | 2015 |
Cooperation, competition and antibiotic resistance in bacterial colonies I Frost, WPJ Smith, S Mitri, AS Millan, Y Davit, JM Osborne, JM Pitt-Francis, ... The ISME journal 12 (6), 1582-1593, 2018 | 182 | 2018 |
Multiresistance in Pasteurella multocida Is Mediated by Coexistence of Small Plasmids A San Millan, JA Escudero, B Gutierrez, L Hidalgo, N Garcia, ... Antimicrobial agents and chemotherapy 53 (8), 3399-3404, 2009 | 148 | 2009 |
Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities A Alonso-del Valle, R León-Sampedro, J Rodríguez-Beltrán, ... Nature communications 12 (1), 2653, 2021 | 145* | 2021 |
Evolutionary pathways and trajectories in antibiotic resistance F Baquero, JL Martinez, V F. Lanza, J Rodríguez-Beltrán, JC Galán, ... Clinical Microbiology Reviews 34 (4), e00050-19, 2021 | 136 | 2021 |
Pervasive transmission of a carbapenem resistance plasmid in the gut microbiota of hospitalized patients R León-Sampedro, J DelaFuente, C Díaz-Agero, T Crellen, P Musicha, ... Nature microbiology 6 (5), 606-616, 2021 | 133 | 2021 |
Integrative analysis of fitness and metabolic effects of plasmids in Pseudomonas aeruginosa PAO1 A San Millan, M Toll-Riera, Q Qi, A Betts, RJ Hopkinson, J McCullagh, ... The ISME journal 12 (12), 3014-3024, 2018 | 106 | 2018 |
Microbial evolution: towards resolving the plasmid paradox RC MacLean, A San Millan Current Biology 25 (17), R764-R767, 2015 | 104 | 2015 |
β-Lactam Resistance in Haemophilus parasuis Is Mediated by Plasmid pB1000 Bearing blaROB-1 A San Millan, JA Escudero, A Catalan, S Nieto, F Farelo, M Gibert, ... Antimicrobial agents and chemotherapy 51 (6), 2260-2264, 2007 | 97 | 2007 |
Small-plasmid-mediated antibiotic resistance is enhanced by increases in plasmid copy number and bacterial fitness A San Millan, A Santos-Lopez, R Ortega-Huedo, C Bernabe-Balas, ... Antimicrobial agents and chemotherapy 59 (6), 3335-3341, 2015 | 93 | 2015 |
Multicopy plasmids allow bacteria to escape from fitness trade-offs during evolutionary innovation J Rodriguez-Beltran, JCR Hernandez-Beltran, J DelaFuente, JA Escudero, ... Nature ecology & evolution 2 (5), 873-881, 2018 | 88 | 2018 |
Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria J Rodríguez-Beltrán, V Sørum, M Toll-Riera, C de la Vega, R Peña-Miller, ... Proceedings of the National Academy of Sciences 117 (27), 15755-15762, 2020 | 66 | 2020 |
Haemophilus influenzae Clinical Isolates with Plasmid pB1000 Bearing blaROB-1: Fitness Cost and Interspecies Dissemination A San Millan, S Garcia-Cobos, JA Escudero, L Hidalgo, B Gutierrez, ... Antimicrobial agents and chemotherapy 54 (4), 1506-1511, 2010 | 61 | 2010 |