High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome S Alsford, DJ Turner, SO Obado, A Sanchez-Flores, L Glover, M Berriman, ... Genome research 21 (6), 915-924, 2011 | 528 | 2011 |
High-throughput decoding of antitrypanosomal drug efficacy and resistance S Alsford, S Eckert, N Baker, L Glover, A Sanchez-Flores, KF Leung, ... Nature 482 (7384), 232, 2012 | 356 | 2012 |
Tagging a T. brucei RRNA locus improves stable transfection efficiency and circumvents inducible expression position effects S Alsford, T Kawahara, L Glover, D Horn Molecular and biochemical parasitology 144 (2), 142-148, 2005 | 192 | 2005 |
Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes N Baker, L Glover, JC Munday, DA Andrés, MP Barrett, HP De Koning, ... Proceedings of the National Academy of Sciences 109 (27), 10996-11001, 2012 | 189 | 2012 |
Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of … JC Munday, AA Eze, N Baker, L Glover, C Clucas, D Aguinaga Andrés, ... Journal of Antimicrobial Chemotherapy 69 (3), 651-663, 2013 | 143 | 2013 |
Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes L Glover, R McCulloch, D Horn Nucleic acids research 36 (8), 2608-2618, 2008 | 128 | 2008 |
DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes L Glover, S Alsford, D Horn PLoS pathogens 9 (3), e1003260, 2013 | 122 | 2013 |
Trypanosomal histone γH2A and the DNA damage response L Glover, D Horn Molecular and biochemical parasitology 183 (1), 78-83, 2012 | 118 | 2012 |
VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes L Glover, S Hutchinson, S Alsford, D Horn Proceedings of the National Academy of Sciences 113 (26), 7225-7230, 2016 | 107 | 2016 |
Microhomology-mediated deletion and gene conversion in African trypanosomes L Glover, J Jun, D Horn Nucleic acids research 39 (4), 1372-1380, 2010 | 92 | 2010 |
Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control L Glover, S Hutchinson, S Alsford, R McCulloch, MC Field, D Horn Cellular microbiology 15 (12), 1984-1993, 2013 | 76 | 2013 |
PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome SG Rudd, L Glover, SK Jozwiakowski, D Horn, AJ Doherty Molecular cell 52 (4), 554-565, 2013 | 70 | 2013 |
Repression of polymerase I‐mediated gene expression at Trypanosoma brucei telomeres L Glover, D Horn EMBO reports 7 (1), 93-99, 2006 | 65 | 2006 |
Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes L Glover, S Alsford, N Baker, DJ Turner, A Sanchez-Flores, S Hutchinson, ... Nature protocols 10 (1), 106, 2015 | 61 | 2015 |
Deletion of a trypanosome telomere leads to loss of silencing and progressive loss of terminal DNA in the absence of cell cycle arrest L Glover, S Alsford, C Beattie, D Horn Nucleic acids research 35 (3), 872-880, 2007 | 58 | 2007 |
Site-specific DNA double-strand breaks greatly increase stable transformation efficiency in Trypanosoma brucei L Glover, D Horn Molecular and biochemical parasitology 166 (2), 194-197, 2009 | 45 | 2009 |
High-resolution analysis of multi-copy variant surface glycoprotein gene expression sites in African trypanosomes S Hutchinson, L Glover, D Horn BMC genomics 17 (1), 806, 2016 | 34 | 2016 |
Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei E Rico, A Ivens, L Glover, D Horn, KR Matthews PLoS pathogens 13 (3), e1006279, 2017 | 28 | 2017 |
Locus-specific control of DNA resection and suppression of subtelomeric VSG recombination by HAT3 in the African trypanosome L Glover, D Horn Nucleic acids research 42 (20), 12600-12613, 2014 | 27 | 2014 |
DNA breaks as triggers for antigenic variation in African trypanosomes S Alsford, D Horn, L Glover Genome biology 10 (6), 223, 2009 | 16 | 2009 |