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Helle Bogetofte
Helle Bogetofte
MD, Ph.D., University of Southern Denmark / Odense University Hospital
Bestätigte E-Mail-Adresse bei health.sdu.dk
Titel
Zitiert von
Zitiert von
Jahr
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease
O Cooper, H Seo, S Andrabi, C Guardia-Laguarta, J Graziotto, ...
Science translational medicine 4 (141), 141ra90-141ra90, 2012
5592012
ER stress and autophagic perturbations lead to elevated extracellular α-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons
HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ...
Stem cell reports 6 (3), 342-356, 2016
3542016
Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons
M Sundberg, H Bogetofte, T Lawson, J Jansson, G Smith, A Astradsson, ...
Stem cells 31 (8), 1548-1562, 2013
2602013
PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons
H Bogetofte, P Jensen, M Ryding, SI Schmidt, J Okarmus, L Ritter, ...
Frontiers in cellular neuroscience 13, 297, 2019
632019
Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation
H Bogetofte, P Jensen, J Okarmus, SI Schmidt, M Agger, M Ryding, ...
Neurobiology of Disease 132, 104581, 2019
352019
Lysosomal perturbations in human dopaminergic neurons derived from induced pluripotent stem cells with PARK2 mutation
J Okarmus, H Bogetofte, SI Schmidt, M Ryding, S García-López, BJ Ryan, ...
Scientific Reports 10 (1), 10278, 2020
312020
Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism
J Okarmus, JF Havelund, M Ryding, SI Schmidt, H Bogetofte, ...
Stem cell reports 16 (6), 1510-1526, 2021
292021
Levodopa therapy for Parkinson's disease: history, current status and perspectives
H Bogetofte, A Alamyar, M Blaabjerg, M Meyer
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2020
292020
Microglia-secreted factors enhance dopaminergic differentiation of tissue-and iPSC-derived human neural stem cells
SI Schmidt, H Bogetofte, L Ritter, JB Agergaard, D Hammerich, ...
Stem Cell Reports 16 (2), 281-294, 2021
232021
REST protects dopaminergic neurons from mitochondrial and α-synuclein oligomer pathology in an alpha synuclein overexpressing BAC-transgenic mouse model
BJ Ryan, N Bengoa-Vergniory, M Williamson, E Kirkiz, R Roberts, ...
Journal of Neuroscience 41 (16), 3731-3746, 2021
202021
The validity of intracerebral hemorrhage diagnoses in the Danish Patient Registry and the Danish Stroke Registry
SM Hald, C Kring Sloth, M Agger, MT Schelde-Olesen, M Højholt, M Hasle, ...
Clinical epidemiology, 1313-1325, 2020
152020
Group I metabotropic glutamate receptors: a potential target for regulation of proliferation and differentiation of an immortalized human neural stem cell line
JL Erichsen, M Blaabjerg, H Bogetofte, AM Serrano, M Meyer
Basic & clinical pharmacology & toxicology 116 (4), 329-336, 2015
142015
Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson’s disease GBA-N370S dopamine neurons
H Bogetofte, BJ Ryan, P Jensen, SI Schmidt, DLE Vergoossen, ...
Cell Reports 42 (3), 2023
12*2023
Activation of group II metabotropic glutamate receptors increases proliferation but does not influence neuronal differentiation of a human neural stem cell line
A Dindler, M Blaabjerg, M Kamand, H Bogetofte, M Meyer
Basic & Clinical Pharmacology & Toxicology 122 (4), 367-372, 2018
42018
Lipotype acquisition during neural development is not recapitulated in stem cell–derived neurons
AB Gopalan, L van Uden, RR Sprenger, NFN Marx, H Bogetofte, ...
Life Science Alliance 7 (5), 2024
12024
Multi-omic analysis of guided and unguided forebrain organoids reveal differences in cellular composition and metabolic profiles
MS Oehlenschlaeger, P Jensen, JF Havelund, M Sutcliffe, SB Elmkvist, ...
bioRxiv, 2023.12. 21.572871, 2023
12023
Feeder free differentiation of A9 and A10 type dopaminergic neurons from human pluripotent stem cells using small molecules
O Cooper, M Sundberg, H Bogetofte, H Seo, M Deleidi, T Osborn, ...
Society for Neuroscience (SFN) Annual Meeting, 2011
2011
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