ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ... Stem cell reports 6 (3), 342-356, 2016 | 302 | 2016 |
Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes C Lang, KR Campbell, BJ Ryan, P Carling, M Attar, J Vowles, ... Cell stem cell 24 (1), 93-106. e6, 2019 | 129 | 2019 |
Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons F Zambon, M Cherubini, HJR Fernandes, C Lang, BJ Ryan, V Volpato, ... Human molecular genetics 28 (12), 2001-2013, 2019 | 111 | 2019 |
Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson’s disease C Sandor, P Robertson, C Lang, A Heger, H Booth, J Vowles, L Witty, ... Human molecular genetics 26 (3), 552-566, 2017 | 66 | 2017 |
αSynuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson’s Disease? D Protter, C Lang, AA Cooper Parkinson’s Disease 2012, 2012 | 46 | 2012 |
What we can learn from iPSC-derived cellular models of Parkinson's disease MC Caiazza, C Lang, R Wade-Martins Progress in Brain Research 252, 3-25, 2020 | 11 | 2020 |