ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ... Stem cell reports 6 (3), 342-356, 2016 | 359 | 2016 |
Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes C Lang, KR Campbell, BJ Ryan, P Carling, M Attar, J Vowles, ... Cell stem cell 24 (1), 93-106. e6, 2019 | 153 | 2019 |
Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons F Zambon, M Cherubini, HJR Fernandes, C Lang, BJ Ryan, V Volpato, ... Human molecular genetics 28 (12), 2001-2013, 2019 | 148 | 2019 |
Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson’s disease C Sandor, P Robertson, C Lang, A Heger, H Booth, J Vowles, L Witty, ... Human molecular genetics 26 (3), 552-566, 2017 | 79 | 2017 |
αSynuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson’s Disease? D Protter, C Lang, AA Cooper Parkinson’s Disease 2012, 2012 | 46 | 2012 |
What we can learn from iPSC-derived cellular models of Parkinson's disease MC Caiazza, C Lang, R Wade-Martins Progress in Brain Research 252, 3-25, 2020 | 14 | 2020 |
Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation QB Do, H Noor, R Marquez-Gomez, KML Cramb, B Ng, A Abbey, ... npj Parkinson's Disease 10 (1), 82, 2024 | 2 | 2024 |
The pathogenic relationship of Alpha Synuclein and Mitochondrial dysfunction in sporadic Parkinson's Disease C Lang UNSW Sydney, 2015 | 1 | 2015 |
Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation QB Do, B Ng, RM Gomez, D Beccano-Kelly, N Ibarra-Aizpura, ... bioRxiv, 2023.03. 01.530566, 2023 | | 2023 |