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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2789 | 2018 |
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression J Yu, J Yu, RS Mani, Q Cao, CJ Brenner, X Cao, X Wang, L Wu Cancer cell 17 (5), 443-454, 2010 | 1016 | 2010 |
A compendium of chromatin contact maps reveals spatially active regions in the human genome AD Schmitt, M Hu, I Jung, Z Xu, Y Qiu, CL Tan, Y Li, S Lin, Y Lin, CL Barr, ... Cell reports 17 (8), 2042-2059, 2016 | 871 | 2016 |
Integrative functional genomic analysis of human brain development and neuropsychiatric risks M Li, G Santpere, Y Imamura Kawasawa, OV Evgrafov, FO Gulden, ... Science 362 (6420), eaat7615, 2018 | 710 | 2018 |
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Circular ecDNA promotes accessible chromatin and high oncogene expression S Wu, KM Turner, N Nguyen, R Raviram, M Erb, J Santini, J Luebeck, ... Nature 575 (7784), 699-703, 2019 | 462 | 2019 |
Genome-wide mapping and analysis of chromosome architecture AD Schmitt, M Hu, B Ren Nature reviews Molecular cell biology 17 (12), 743-755, 2016 | 402 | 2016 |
Widespread rearrangement of 3D chromatin organization underlies polycomb-mediated stress-induced silencing L Li, X Lyu, C Hou, N Takenaka, HQ Nguyen, CT Ong, C Cubeñas-Potts, ... Molecular cell 58 (2), 216-231, 2015 | 341 | 2015 |
HiCNorm: removing biases in Hi-C data via Poisson regression M Hu, K Deng, S Selvaraj, Z Qin, B Ren, JS Liu Bioinformatics 28 (23), 3131-3133, 2012 | 294 | 2012 |
An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome C Zhu, M Yu, H Huang, I Juric, A Abnousi, R Hu, J Lucero, MM Behrens, ... Nature structural & molecular biology 26 (11), 1063-1070, 2019 | 290 | 2019 |
Emergency Department–Initiated Palliative Care in Advanced Cancer: A Randomized Clinical Trial CR Grudzen, LD Richardson, PN Johnson, M Hu, B Wang, JM Ortiz, ... JAMA Oncology, 2016 | 263 | 2016 |
Bayesian Inference of Spatial Organizations of Chromosomes M Hu, K Deng, Z Qin, J Dixon, S Selvaraj, J Fang, B Ren, JS Liu PLoS computational biology 9 (1), e1002893, 2013 | 256 | 2013 |
Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation N Kubo, H Ishii, X Xiong, S Bianco, F Meitinger, R Hu, JD Hocker, ... Nature structural & molecular biology 28 (2), 152-161, 2021 | 247 | 2021 |
Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer JH Kim, SM Dhanasekaran, JR Prensner, X Cao, D Robinson, ... Genome research 21 (7), 1028-1041, 2011 | 220 | 2011 |
Enhancing Hi-C data resolution with deep convolutional neural network HiCPlus Y Zhang, L An, J Xu, B Zhang, WJ Zheng, M Hu, J Tang, F Yue Nature communications 9 (1), 750, 2018 | 193 | 2018 |
Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers J Yan, SAA Chen, A Local, T Liu, Y Qiu, KM Dorighi, S Preissl, CM Rivera, ... Cell research 28 (2), 204-220, 2018 | 187 | 2018 |
Cooperation between Polycomb and androgen receptor during oncogenic transformation JC Zhao, J Yu, C Runkle, L Wu, M Hu, D Wu, JS Liu, Q Wang, ZS Qin, ... Genome Research 22 (2), 322-331, 2012 | 160 | 2012 |
Robust Hi-C maps of enhancer-promoter interactions reveal the function of non-coding genome in neural development and diseases L Lu, X Liu, WK Huang, P Giusti-Rodríguez, J Cui, S Zhang, W Xu, Z Wen, ... Molecular cell 79 (3), 521-534. e15, 2020 | 148 | 2020 |
HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data Z Qin, J Yu, J Shen, C Maher, M Hu, S Kalyana-Sundaram, J Yu, ... BMC bioinformatics 11 (1), 369, 2010 | 148 | 2010 |