| Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease BJ Ryan, S Hoek, EA Fon, R Wade-Martins Trends in biochemical sciences 40 (4), 200-210, 2015 | 586 | 2015 |
| Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model S Janezic, S Threlfell, PD Dodson, MJ Dowie, TN Taylor, D Potgieter, ... Proceedings of the National Academy of Sciences 110 (42), E4016-E4025, 2013 | 355 | 2013 |
| ER stress and autophagic perturbations lead to elevated extracellular α-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ... Stem cell reports 6 (3), 342-356, 2016 | 350 | 2016 |
| Mitochondrial dysfunction and mitophagy in Parkinson’s disease: from mechanism to therapy AB Malpartida, M Williamson, DP Narendra, R Wade-Martins, BJ Ryan Trends in biochemical sciences 46 (4), 329-343, 2021 | 298 | 2021 |
| Single-cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes C Lang*, KR Campbell*, BJ Ryan, P Carling, M Attar, J Vowles, ... Cell stem cell 24 (1), 93-106. e6, 2019 | 150 | 2019 |
| Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons F Zambon, M Cherubini, HJR Fernandes, C Lang, BJ Ryan, V Volpato, ... Human Molecular Genetics 28 (12), 2001-2013, 2019 | 140 | 2019 |
| Autoantibodies to posttranslational modifications in rheumatoid arthritis AN Burska, L Hunt, M Boissinot, R Strollo, BJ Ryan, E Vital, A Nissim, ... Mediators of Inflammation 2014, 2014 | 120 | 2014 |
| Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease PG Winyard, B Ryan, P Eggleton, A Nissim, E Taylor, ML Lo Faro, ... Biochemical society transactions 39 (5), 1226-1232, 2011 | 111* | 2011 |
| Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases BJ Ryan, A Nissim, PG Winyard Redox biology 2, 715-724, 2014 | 109 | 2014 |
| Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells AM Smith, C Depp, BJ Ryan, GI Johnston, J Alegre‐Abarrategui, S Evetts, ... Movement Disorders 33 (10), 1580-1590, 2018 | 89 | 2018 |
| Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)–mediated apoptosis of T cells JM Tarr, PG Winyard, B Ryan, LW Harries, R Haigh, N Viner, P Eggleton Arthritis & Rheumatism 62 (10), 2919-2929, 2010 | 73 | 2010 |
| PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons H Bogetofte, P Jensen, M Ryding, SI Schmidt, J Okarmus, L Ritter, ... Frontiers in cellular neuroscience 13, 297, 2019 | 63 | 2019 |
| Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse TN Taylor, D Potgieter, S Anwar, SL Senior, S Janezic, S Threlfell, B Ryan, ... Neurobiology of disease 62, 193-207, 2014 | 60 | 2014 |
| A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance J Bailey, A Shaw, R Fischer, BJ Ryan, BM Kessler, J McCullagh, ... Free Radical Biology and Medicine 104, 214-225, 2017 | 59 | 2017 |
| Oxidative and other posttranslational modifications in extracellular vesicle biology K Szabó-Taylor, B Ryan, X Osteikoetxea, TG Szabó, B Sódar, M Holub, ... Seminars in cell & developmental biology 40, 8-16, 2015 | 55 | 2015 |
| α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease BJ Ryan, LL Lourenço-Venda, MJ Crabtree, AB Hale, KM Channon, ... Free Radical Biology and Medicine 67, 58-68, 2014 | 36 | 2014 |
| Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation H Bogetofte, P Jensen, J Okarmus, SI Schmidt, M Agger, M Ryding, ... Neurobiology of Disease 132, 104581, 2019 | 35 | 2019 |
| Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson’s disease H Keane*, BJ Ryan*, B Jackson, A Whitmore, R Wade-Martins Scientific reports 5 (1), 17004, 2015 | 34 | 2015 |
| Detection and isolation of human serum autoantibodies that recognize oxidatively modified autoantigens P Eggleton, A Nissim, BJ Ryan, M Whiteman, PG Winyard Free radical biology and medicine 57, 79-91, 2013 | 34 | 2013 |
| A requirement for Gch1 and tetrahydrobiopterin in embryonic development G Douglas, AB Hale, MJ Crabtree, BJ Ryan, A Hansler, K Watschinger, ... Developmental biology 399 (1), 129-138, 2015 | 32 | 2015 |
Paul WinyardUniversity of ExeterBestätigte E-Mail-Adresse bei exeter.ac.uk
