| Rapid and efficient induction of functional astrocytes from human pluripotent stem cells I Canals, A Ginisty, E Quist, R Timmerman, J Fritze, G Miskinyte, E Monni, ... Nature methods 15 (9), 693-696, 2018 | 204 | 2018 |
| Therapeutic strategies based on modified U1 snRNAs and chaperones for Sanfilippo C splicing mutations L Matos, I Canals, L Dridi, Y Choi, MJ Prata, P Jordan, LR Desviat, ... Orphanet journal of rare diseases 9, 1-12, 2014 | 53 | 2014 |
| Sanfilippo syndrome: molecular basis, disease models and therapeutic approaches N Benetó, L Vilageliu, D Grinberg, I Canals International Journal of Molecular Sciences 21 (21), 7819, 2020 | 45 | 2020 |
| Activity and high-order effective connectivity alterations in Sanfilippo C patient-specific neuronal networks I Canals, J Soriano, JG Orlandi, R Torrent, Y Richaud-Patin, ... Stem cell reports 5 (4), 546-557, 2015 | 41 | 2015 |
| EXTL2 and EXTL3 inhibition with siRNAs as a promising substrate reduction therapy for Sanfilippo C syndrome I Canals, N Benetó, M Cozar, L Vilageliu, D Grinberg Scientific reports 5 (1), 13654, 2015 | 36 | 2015 |
| Molecular analysis of Sanfilippo syndrome type C in Spain: seven novel HGSNAT mutations and characterization of the mutant alleles I Canals, SC Elalaoui, M Pineda, V Delgadillo, M Szlago, IC Jaouad, ... Clinical Genetics 80 (4), 367-374, 2011 | 34 | 2011 |
| Mitochondrial dysfunction and calcium dysregulation in leigh syndrome induced pluripotent stem cell derived neurons T Galera-Monge, F Zurita-Díaz, I Canals, M Grønning Hansen, ... International Journal of Molecular Sciences 21 (9), 3191, 2020 | 25 | 2020 |
| Transcription factor-based direct conversion of human fibroblasts to functional astrocytes E Quist, F Trovato, N Avaliani, OG Zetterdahl, A Gonzalez-Ramos, ... Stem Cell Reports 17 (7), 1620-1635, 2022 | 20 | 2022 |
| Neuronal and astrocytic differentiation from Sanfilippo C syndrome iPSCs for disease modeling and drug development N Benetó, M Cozar, L Castilla-Vallmanya, OG Zetterdahl, M Sacultanu, ... Journal of Clinical Medicine 9 (3), 644, 2020 | 16 | 2020 |
| Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence L Oburoglu, E Mansell, I Canals, V Sigurdsson, C Guibentif, S Soneji, ... EMBO reports 23 (2), e54384, 2022 | 15 | 2022 |
| NGN2 mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities AM Tolomeo, C Laterza, E Grespan, F Michielin, I Canals, Z Kokaia, ... Frontiers in Cellular Neuroscience 15, 602888, 2021 | 14 | 2021 |
| In vitro functional characterization of human neurons and astrocytes using calcium imaging and electrophysiology MG Hansen, D Tornero, I Canals, H Ahlenius, Z Kokaia Neural stem cells: methods and protocols, 73-88, 2019 | 12 | 2019 |
| Transcription factor programming of human pluripotent stem cells to functionally mature astrocytes for monocultures and cocultures with neurons E Quist, H Ahlenius, I Canals Neural Reprogramming: Methods and Protocols, 133-148, 2021 | 11 | 2021 |
| Transcription factor-based strategies to generate neural cell types from human pluripotent stem cells I Canals, E Quist, H Ahlenius Cellular Reprogramming 23 (4), 206-220, 2021 | 10 | 2021 |
| Generation of two compound heterozygous HGSNAT-mutated lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo C syndrome N Benetó, M Cozar, M García-Morant, E Creus Bachiller, ... Stem Cell Research, 2019, vol. 41, num. 101616, p. 1-5, 2019 | 10 | 2019 |
| Serial magnetic resonance imaging and neurophysiological studies in multiple sulphatase deficiency DI Zafeiriou, E Vargiami, K Papadopoulou, E Dimitriou, I Mavridou, ... European Journal of Paediatric Neurology 12 (3), 190-194, 2008 | 8 | 2008 |
| Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome N Benetó, M Cozar, L Gort i Mas, L Pacheco, L Vilageliu i Arqués, ... Stem Cell Research, 2020, vol. 42, p. 101668, 2020 | 7 | 2020 |
| FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis A Monsalve, I Canals, L Oburoglu Frontiers in cell and developmental biology 10, 1039636, 2022 | 5 | 2022 |
| CRISPR/Cas9 genome engineering in human pluripotent stem cells for modeling of neurological disorders I Canals, H Ahlenius Neural Reprogramming: Methods and Protocols, 237-251, 2021 | 5 | 2021 |
| Transcription Factor–Forced Astrocytic Differentiation Impairs Human Glioblastoma Growth In Vitro and In Vivo F Trovato, FR Stefani, J Li, OG Zetterdahl, I Canals, H Ahlenius, ... Molecular Cancer Therapeutics 22 (2), 274-286, 2023 | 4 | 2023 |
