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Jeremy R. Keown
Jeremy R. Keown
Assistant Professor, University of Warwick, UK
Bestätigte E-Mail-Adresse bei warwick.ac.uk - Startseite
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Zitiert von
Zitiert von
Jahr
Structures of influenza A virus RNA polymerase offer insight into viral genome replication
H Fan, AP Walker, L Carrique, JR Keown, I Serna Martin, D Karia, ...
Nature 573 (7773), 287-290, 2019
1712019
Host ANP32A mediates the assembly of the influenza virus replicase
L Carrique, H Fan, AP Walker, JR Keown, J Sharps, E Staller, WS Barclay, ...
Nature 587 (7835), 638-643, 2020
982020
An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis
TM Ryan, J Trewhella, JM Murphy, JR Keown, L Casey, FG Pearce, ...
Journal of applied crystallography 51 (1), 97-111, 2018
782018
Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification
HT Baddock, S Brolih, Y Yosaatmadja, M Ratnaweera, M Bielinski, ...
Nucleic acids research 50 (3), 1484-1500, 2022
552022
A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5α and mammalian autophagy-related ATG8 proteins
JR Keown, MM Black, A Ferron, M Yap, MJ Barnett, FG Pearce, JP Stoye, ...
Journal of Biological Chemistry 293 (47), 18378-18386, 2018
522018
Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins
M Renner, W Dejnirattisai, L Carrique, IS Martin, D Karia, SL Ilca, SF Ho, ...
Nature Communications 12 (1), 1238, 2021
512021
Small oligomers of ribulose-bisphosphate carboxylase/oxygenase (Rubisco) activase are required for biological activity
JR Keown, MDW Griffin, HDT Mertens, FG Pearce
Journal of Biological Chemistry 288 (28), 20607-20615, 2013
432013
The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme
AP Walker, H Fan, JR Keown, ML Knight, JM Grimes, E Fodor
Nucleic acids research 49 (22), 13019-13030, 2021
422021
Characterization of spinach ribulose-1, 5-bisphosphate carboxylase/oxygenase activase isoforms reveals hexameric assemblies with increased thermal stability
JR Keown, FG Pearce
Biochemical Journal 464 (3), 413-423, 2014
382014
Parallel evolution in the emergence of highly pathogenic avian influenza A viruses
M Escalera-Zamudio, M Golden, B Gutiérrez, J Thézé, JR Keown, ...
Nature Communications 11 (1), 5511, 2020
372020
A structural understanding of influenza virus genome replication
Z Zhu, E Fodor, JR Keown
Trends in microbiology 31 (3), 308-319, 2023
362023
Characterisation of assembly and ubiquitylation by the RBCC motif of Trim5α
JR Keown, JX Yang, J Douglas, DC Goldstone
Scientific reports 6 (1), 26837, 2016
362016
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
P Brown, Y Zhou
Database 2019, baz085, 2019
342019
A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family
Y Sun, JR Keown, MM Black, C Raclot, N Demarais, D Trono, P Turelli, ...
Journal of molecular biology 431 (14), 2511-2527, 2019
292019
The Protozoan Trichomonas vaginalis Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases
J Pinheiro, J Biboy, W Vollmer, RP Hirt, JR Keown, A Artuyants, MM Black, ...
MBio 9 (6), 10.1128/mbio. 01784-18, 2018
252018
Design, synthesis, and biological evaluation of novel indoles targeting the influenza PB2 cap binding region
DC McGowan, W Balemans, W Embrechts, M Motte, JR Keown, C Buyck, ...
Journal of medicinal chemistry 62 (21), 9680-9690, 2019
232019
Crystal structure of the Trim5α Bbox2 domain from rhesus macaques describes a plastic oligomerisation interface
JR Keown, DC Goldstone
Journal of structural biology 195 (3), 282-285, 2016
212016
Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases
AP Walker, H Fan, JR Keown, V Margitich, JM Grimes, E Fodor, ...
BioRxiv, 2020
202020
Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies
JR Keown, Z Zhu, L Carrique, H Fan, AP Walker, I Serna Martin, E Pardon, ...
Nature communications 13 (1), 251, 2022
152022
The C-terminal domains of the PB2 subunit of the influenza A virus RNA polymerase directly interact with cellular GTPase Rab11a
H Veler, H Fan, JR Keown, J Sharps, M Fournier, JM Grimes, E Fodor
Journal of Virology 96 (5), e01979-21, 2022
142022
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