Triggering the interferon antiviral response through an IKK-related pathway S Sharma, BR TenOever, N Grandvaux, GP Zhou, R Lin, J Hiscott Science 300 (5622), 1148-1151, 2003 | 1761 | 2003 |
Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation R Lin, C Heylbroeck, PM Pitha, J Hiscott Molecular and cellular biology 18 (5), 2986-2996, 1998 | 1088 | 1998 |
Interferon regulatory factors: the next generation Y Mamane, C Heylbroeck, P Génin, M Algarté, MJ Servant, C LePage, ... Gene 237 (1), 1-14, 1999 | 723 | 1999 |
Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes N Grandvaux, MJ Servant, B tenOever, GC Sen, S Balachandran, ... Journal of virology 76 (11), 5532-5539, 2002 | 506 | 2002 |
Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus SG Devaraj, N Wang, Z Chen, Z Chen, M Tseng, N Barretto, R Lin, ... Journal of Biological Chemistry 282 (44), 32208-32221, 2007 | 417 | 2007 |
Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains R Lin, Y Mamane, J Hiscott Molecular and cellular biology 19 (4), 2465-2474, 1999 | 370 | 1999 |
Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription R Lin, C Heylbroeck, P Genin, PM Pitha, J Hiscott Molecular and cellular biology 19 (2), 959-966, 1999 | 362 | 1999 |
The NEMO adaptor bridges the nuclear factor-κB and interferon regulatory factor signaling pathways T Zhao, L Yang, Q Sun, M Arguello, DW Ballard, J Hiscott, R Lin Nature immunology 8 (6), 592-600, 2007 | 356 | 2007 |
Regulation of type I interferon gene expression by interferon regulatory factor-3 SL Schafer, R Lin, PA Moore, J Hiscott, PM Pitha Journal of Biological Chemistry 273 (5), 2714-2720, 1998 | 350 | 1998 |
Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory … R Lin, P Génin, Y Mamane, J Hiscott Molecular and Cellular Biology 20 (17), 6342-6353, 2000 | 340 | 2000 |
The herpes simplex virus ICP0 RING finger domain inhibits IRF3-and IRF7-mediated activation of interferon-stimulated genes R Lin, RS Noyce, SE Collins, RD Everett, KL Mossman Journal of virology 78 (4), 1675-1684, 2004 | 337 | 2004 |
Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3 YT Juang, W Lowther, M Kellum, WC Au, R Lin, J Hiscott, PM Pitha Proceedings of the National Academy of Sciences 95 (17), 9837-9842, 1998 | 336 | 1998 |
Triggering the interferon response: the role of IRF-3 transcription factor J Hiscott, P Pitha, P Genin, H Nguyen, C Heylbroeck, Y Mamane, ... Journal of interferon & cytokine research 19 (1), 1-13, 1999 | 310 | 1999 |
Multiple regulatory domains control IRF-7 activity in response to virus infection R Lin, Y Mamane, J Hiscott Journal of Biological Chemistry 275 (44), 34320-34327, 2000 | 300 | 2000 |
Regulation of RANTES chemokine gene expression requires cooperativity between NF-κB and IFN-regulatory factor transcription factors P Génin, M Algarté, P Roof, R Lin, J Hiscott The Journal of Immunology 164 (10), 5352-5361, 2000 | 272 | 2000 |
Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKε molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage R Lin, J Lacoste, P Nakhaei, Q Sun, L Yang, S Paz, P Wilkinson, ... Journal of virology 80 (12), 6072-6083, 2006 | 271 | 2006 |
Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability R Lin, P Beauparlant, C Makris, S Meloche, J Hiscott Molecular and Cellular Biology 16 (4), 1401-1409, 1996 | 270 | 1996 |
Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA MJ Servant, N Grandvaux, D Duguay, R Lin, J Hiscott Journal of Biological Chemistry 278 (11), 9441-9447, 2003 | 268 | 2003 |
HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators R Lin, P Genin, Y Mamane, M Sgarbanti, A Battistini, WJ Harrington, ... Oncogene 20 (7), 800-811, 2001 | 260 | 2001 |
Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20 R Lin, L Yang, P Nakhaei, Q Sun, E Sharif-Askari, I Julkunen, J Hiscott Journal of Biological Chemistry 281 (4), 2095-2103, 2006 | 256 | 2006 |