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Christian Holland
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Benchmark and integration of resources for the estimation of human transcription factor activities
L Garcia-Alonso, CH Holland, MM Ibrahim, D Turei, J Saez-Rodriguez
Genome research 29 (8), 1363-1375, 2019
6762019
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
CH Holland, J Tanevski, J Perales-Patón, J Gleixner, MP Kumar, E Mereu, ...
Genome Biology 21 (1), 36, 2020
2382020
decoupleR: Ensemble of computational methods to infer biological activities from omics data
P Badia-i-Mompel, J Vélez Santiago, J Braunger, C Geiss, D Dimitrov, ...
Bioinformatics Advances 2 (1), vbac016, 2022
1912022
Transfer of regulatory knowledge from human to mouse for functional genomics analysis
CH Holland, B Szalai, J Saez-Rodriguez
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1863 (6), 194431, 2020
1132020
Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis
A Mohs, T Otto, KM Schneider, M Peltzer, M Boekschoten, CH Holland, ...
Journal of Hepatology 74 (3), 638-648, 2021
1052021
Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment
KM Schneider, A Mohs, W Gui, EJC Galvez, LS Candels, L Hoenicke, ...
Nature Communications 13 (1), 3964, 2022
1002022
Influence of Liver Fibrosis on Lobular Zonation
A Ghallab, M Myllys, C H Holland, A Zaza, W Murad, R Hassan, ...
Cells 8 (12), 1556, 2019
602019
Signatures of cell death and proliferation in perturbation transcriptomics data—from confounding factor to effective prediction
B Szalai, V Subramanian, CH Holland, R Alföldi, LG Puskás, ...
Nucleic acids research 47 (19), 10010-10026, 2019
512019
Consensus Transcriptional Landscape of Human End‐Stage Heart Failure
RO Ramirez Flores, JD Lanzer, CH Holland, F Leuschner, P Most, ...
Journal of the American Heart Association 10 (7), e019667, 2021
442021
Transcriptomic Cross‐Species Analysis of Chronic Liver Disease Reveals Consistent Regulation Between Humans and Mice
CH Holland, RO Ramirez Flores, M Myllys, R Hassan, K Edlund, ...
Hepatology Communications 6 (1), 161-177, 2022
352022
Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression
A Ghallab, M Myllys, A Friebel, J Duda, K Edlund, E Halilbasic, M Vucur, ...
Cells 10 (10), 2516, 2021
352021
A functional landscape of CKD entities from public transcriptomic data
F Tajti, C Kuppe, A Antoranz, MM Ibrahim, H Kim, F Ceccarelli, ...
Kidney International Reports 5 (2), 211-224, 2020
20*2020
Transcription Factor Activity Inference in Systemic Lupus Erythematosus
R Lopez-Dominguez, D Toro-Dominguez, J Martorell-Marugan, ...
Life 11 (4), 299, 2021
112021
Stabilization but no functional influence of HIF-1α expression in the intestinal epithelium during Salmonella Typhimurium infection
L Robrahn, A Dupont, S Jumpertz, K Zhang, CH Holland, J Guillaume, ...
Infection and Immunity 90 (2), e00222-21, 2022
82022
FUNKI: interactive functional footprint-based analysis of omics data
R Hernansaiz-Ballesteros, CH Holland, A Dugourd, J Saez-Rodriguez
Bioinformatics 38 (7), 2075-2076, 2022
22022
Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation
S Hammad, C Ogris, A Othman, P Erdoesi, W Schmidt-Heck, I Biermayer, ...
Cell Death & Disease 14 (7), 414, 2023
12023
Increased sinusoidal export of drug glucuronides is a compensative mechanism in liver cirrhosis of mice
R Fendt, A Ghallab, M Myllys, U Hofmann, R Hassan, Z Hobloss, ...
Frontiers in Pharmacology 14, 2023
2023
Novel short-termed mouse model of intrahepatic cholangiocarcinoma by orthotopic transplantation of Hep-55.1 C in mice with human homology
TH Wirtz, EF Brandt, P Fischer, C Holland, A Röth, M Baues, JN May, ...
Zeitschrift für Gastroenterologie 60 (01), e34-e34, 2022
2022
From gene expression to pathway and transcription factor activities to study chronic liver diseases
CH Holland
2021
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