Kourosh Ebrahimi
Kourosh Ebrahimi
Institute of Pharmaceutical Science, King's College London,
Bestätigte E-Mail-Adresse bei - Startseite
Zitiert von
Zitiert von
Unity in the biochemistry of the iron-storage proteins ferritin and bacterioferritin
K Honarmand Ebrahimi, PL Hagedoorn, WR Hagen
Chemical reviews 115 (1), 295-326, 2015
The catalytic center of ferritin regulates iron storage via Fe(II)-Fe(III) displacement
K Honarmand Ebrahimi, E Bill, PL Hagedoorn, WR Hagen
Nature chemical biology 8 (11), 941-948, 2012
A conserved tyrosine in ferritin is a molecular capacitor
KH Ebrahimi, PL Hagedoorn, WR Hagen
ChemBioChem 14 (9), 1123-1133, 2013
Catalysis of iron core formation in Pyrococcus furiosus ferritin
K Honarmand Ebrahimi, PL Hagedoorn, JA Jongejan, WR Hagen
JBIC Journal of Biological Inorganic Chemistry 14, 1265-1274, 2009
The workings of ferritin: a crossroad of opinions
WR Hagen, PL Hagedoorn, K Honarmand Ebrahimi
Metallomics 9 (6), 595-605, 2017
A unifying view of the broad-spectrum antiviral activity of RSAD2 (viperin) based on its radical-SAM chemistry
K Honarmand Ebrahimi
Metallomics 10 (4), 539-552, 2018
Mechanistic insights into the three steps of poly (ADP-ribosylation) reversal
JGM Rack, Q Liu, V Zorzini, J Voorneveld, A Ariza, ...
Nature Communications 12 (1), 4581, 2021
The radical‐SAM enzyme Viperin catalyzes reductive addition of a 5′‐deoxyadenosyl radical to UDP‐glucose in vitro
K Honarmand Ebrahimi, SB Carr, J McCullagh, J Wickens, NH Rees, ...
FEBS Letters, 2017
A synthetic peptide with the putative iron binding motif of amyloid precursor protein (APP) does not catalytically oxidize iron
KH Ebrahimi, PL Hagedoorn, WR Hagen
Public Library of Science 7 (8), e40287, 2012
SARS‐CoV‐2 spike glycoprotein‐binding proteins expressed by upper respiratory tract bacteria may prevent severe viral infection
K Honarmand Ebrahimi
FEBS Letters, 2020
The amyloid precursor protein (APP) does not have a ferroxidase site in its E2 domain
K Honarmand Ebrahimi, C Dienemann, S Hoefgen, ME Than, ...
PLoS One 8 (8), e72177, 2013
Viperin, through its radical‐SAM activity, depletes cellular nucleotide pools and interferes with mitochondrial metabolism to inhibit viral replication
KH Ebrahimi, D Howie, JS Rowbotham, J McCullagh, FA Armstrong, ...
FEBS letters 594 (10), 1624-1630, 2020
ddhCTP produced by the radical‐SAM activity of RSAD2 (viperin) inhibits the NAD+‐dependent activity of enzymes to modulate metabolism
K Honarmand Ebrahimi, J Vowles, C Browne, J McCullagh, WS James
FEBS letters 594 (10), 1631-1644, 2020
Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics
TM Quinn, EE Gaughan, A Bruce, J Antonelli, R O'Connor, F Li, ...
EBioMedicine 76, 103856, 2022
Inhibition and stimulation of formation of the ferroxidase center and the iron core in Pyrococcus furiosus ferritin
K Honarmand Ebrahimi, PL Hagedoorn, WR Hagen
JBIC Journal of Biological Inorganic Chemistry 15, 1243-1253, 2010
Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium
A Vaughan-Jackson, S Stodolak, KH Ebrahimi, C Browne, PK Reardon, ...
Stem cell reports 16 (7), 1735-1748, 2021
A double-mimetic peptide efficiently neutralizes HIV-1 by bridging the CD4-and coreceptor-binding sites of gp120
BD Quinlan, VR Joshi, MR Gardner, KH Ebrahimi, M Farzan
Journal of Virology 88 (6), 3353-3358, 2014
A novel mechanism of iron-core formation by Pyrococcus furiosus archaeoferritin, a member of an uncharacterized branch of the ferritin-like superfamily
KH Ebrahimi, PL Hagedoorn, L van der Weel, PDEM Verhaert, WR Hagen
JBIC Journal of Biological Inorganic Chemistry 17, 975-985, 2012
Phosphate accelerates displacement of Fe (III) by Fe (II) in the ferroxidase center of Pyrococcus furiosus ferritin
KH Ebrahimi, PL Hagedoorn, WR Hagen
FEBS letters 587 (2), 220-225, 2013
Mechanism of diol dehydration by a promiscuous radical‐SAM enzyme homologue of the antiviral enzyme viperin (RSAD2)
K Honarmand Ebrahimi, JS Rowbotham, J McCullagh, WS James
ChemBioChem 21, 2020
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