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Thomas Orasch
Thomas Orasch
Leibniz Institue for Natural Product Research and Infection Biology - HKI -
Bestätigte E-Mail-Adresse bei leibniz-hki.de
Titel
Zitiert von
Zitiert von
Jahr
Bronchoalveolar lavage triacetylfusarinine C (TAFC) determination for diagnosis of invasive pulmonary aspergillosis in patients with hematological malignancies
T Orascha, J Prattesa, K Faserl, S Eigl, W Düttmann, H Lindner, H Haas, ...
The Journal of infection 75 (4), 370, 2017
512017
Triacetylfusarinine C: A urine biomarker for diagnosis of invasive aspergillosis
M Hoenigl, T Orasch, K Faserl, J Prattes, J Loeffler, J Springer, F Gsaller, ...
Journal of Infection 78 (2), 150-157, 2019
472019
The Zn2Cys6-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus
N Long, T Orasch, S Zhang, L Gao, X Xu, P Hortschansky, J Ye, F Zhang, ...
PLoS Genetics 14 (10), e1007762, 2018
402018
Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores
J Pfister, D Summer, M Petrik, M Khoylou, A Lichius, P Kaeopookum, ...
Biomolecules 10 (2), 168, 2020
332020
The leucine biosynthetic pathway is crucial for adaptation to iron starvation and virulence in Aspergillus fumigatus
T Orasch, AM Dietl, Y Shadkchan, U Binder, I Bauer, C Lass-Flörl, ...
Virulence 10 (1), 925-934, 2019
252019
Modifying the siderophore triacetylfusarinine C for molecular imaging of fungal infection
P Kaeopookum, D Summer, J Pfister, T Orasch, BE Lechner, M Petrik, ...
Molecular imaging and biology 21, 1097-1106, 2019
232019
The Siderophore Transporters Sit1 and Sit2 Are Essential for Utilization of Ferrichrome-, Ferrioxamine- and Coprogen-Type Siderophores in Aspergillus fumigatus
M Aguiar, T Orasch, M Misslinger, AM Dietl, F Gsaller, H Haas
Journal of Fungi 7 (9), 768, 2021
212021
Exploiting the Concept of Multivalency with 68Ga- and 89Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression
D Summer, C Rangger, M Klingler, P Laverman, GM Franssen, ...
Contrast Media & Molecular Imaging 2018, 2018
212018
The Lysine Deacetylase RpdA Is Essential for Virulence in Aspergillus fumigatus
I Bauer, M Misslinger, Y Shadkchan, AM Dietl, V Petzer, T Orasch, B Abt, ...
Frontiers in microbiology 10, 2773, 2019
202019
Caspofungin functionalized polymethacrylates with antifungal properties
J Alex, K González, T Kindel, P Bellstedt, C Weber, T Heinekamp, ...
Biomacromolecules 21 (6), 2104-2115, 2020
142020
Rapid detection of the aspergillosis biomarker triacetylfusarinine C using interference-enhanced Raman spectroscopy
S Pahlow, T Orasch, O Žukovskaja, T Bocklitz, H Haas, K Weber
Analytical and Bioanalytical Chemistry 412, 6351-6360, 2020
102020
Uptake of the siderophore triacetylfusarinine C, but not fusarinine C, is crucial for virulence of Aspergillus fumigatus
M Aguiar, T Orasch, Y Shadkchan, P Caballero, J Pfister, ...
MBio 13 (5), e02192-22, 2022
92022
The lysine deacetylase RpdA is essential for virulence in Aspergillus fumigatus. Front Microbiol 10: 2773
I Bauer, M Misslinger, Y Shadkchan, AM Dietl, V Petzer, T Orasch, B Abt, ...
62019
The leucine biosynthetic pathway is crucial for adaptation to iron starvation and virulence in Aspergillus fumigatus. Virulence 10: 925–934
T Orasch, AM Dietl, Y Shadkchan, U Binder, I Bauer, C Lass-Flörl
Taylor & Francis, 2019
52019
The lipid raft-associated protein stomatin is required for accumulation of dectin-1 in the phagosomal membrane and for full activity of macrophages against Aspergillus fumigatus
M Goldmann, F Schmidt, Z Cseresnyés, T Orasch, S Jahreis, S Hartung, ...
Msphere 8 (1), e00523-22, 2023
32023
Polymer-based particles against pathogenic fungi: A non-uptake delivery of compounds
T Orasch, G Gangapurwala, A Vollrath, K González, J Alex, A De San Luis, ...
Biomaterials Advances 146, 213300, 2023
22023
Diagnostic performance of bronchoalveolar lavage triacetylfusarinine C (TAFC) determination for invasive pulmonary aspergillosis in patients with hematological malignancies
J Prattes, T Orasch, S Eigl, S Heldt, W Duettmann, K Faserl, H Lindner, ...
Open Forum Infectious Diseases 3 (suppl_1), 1558, 2016
22016
Targeting of phagolysosomes containing conidia of the fungus Aspergillus fumigatus with polymeric particles
K González, G Gangapurwala, J Alex, A Vollrath, Z Cseresnyés, C Weber, ...
Applied Microbiology and Biotechnology 107 (2), 819-834, 2023
12023
Research Article Exploiting the Concept of Multivalency with 68 Ga-and 89 Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression
D Summer, C Rangger, M Klingler, P Laverman, GM Franssen, ...
12018
Triacetylfusarinine C determination in urine samples from hematological malignancy patients: a potential new biomarker for invasive aspergillosis
J Prattes, T Orasch, K Faserl, H Lindner, F Reischies, W Duettmann, ...
MYCOSES 60, 35-35, 2017
12017
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