Timothy M. Ryan
Timothy M. Ryan
Instrument Scientist, SAXS/WAXS, Australian Synchrotron
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
The role of metallobiology and amyloid‐β peptides in Alzheimer’s disease
BR Roberts, TM Ryan, AI Bush, CL Masters, JA Duce
Journal of Neurochemistry 120, 149, 2012
Utility of an improved model of amyloid-beta (Abeta1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease
G McColl, BR Roberts, TL Pukala, VB Kenche, CM Roberts, CD Link, ...
Molecular Neurodegeneration 7 (1), 57, 2012
2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update
J Trewhella, AP Duff, D Durand, F Gabel, JM Guss, WA Hendrickson, ...
Acta Crystallographica Section D: Structural Biology 73 (9), 710-728, 2017
Improved radiation dose efficiency in solution SAXS using a sheath flow sample environment
N Kirby, N Cowieson, AM Hawley, ST Mudie, DJ McGillivray, M Kusel, ...
Acta Crystallographica Section D: Structural Biology 72 (12), 1254-1266, 2016
Biochemically-defined pools of amyloid-β in sporadic Alzheimer’s disease: correlation with amyloid PET
BR Roberts, M Lind, AZ Wagen, A Rembach, T Frugier, QX Li, TM Ryan, ...
Brain 140 (5), 1486-1498, 2017
Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization
TM Ryan, J Caine, HDT Mertens, N Kirby, J Nigro, K Breheney, ...
PeerJ 1, e73, 2013
Stabilization of nontoxic Aβ-oligomers: insights into the mechanism of action of hydroxyquinolines in Alzheimer's disease
TM Ryan, BR Roberts, G McColl, DJ Hare, PA Doble, QX Li, M Lind, ...
Journal of Neuroscience 35 (7), 2871-2884, 2015
Nanostructure of electrospun collagen: do electrospun collagen fibers form native structures?
KH Sizeland, KA Hofman, IC Hallett, DE Martin, J Potgieter, NM Kirby, ...
Materialia 3, 90-96, 2018
Metalloproteomics: Principles, challenges and applications to neurodegeneration
BR Roberts, A Lothian, DJ Hare, CL Masters, TM Ryan, R Grimm
Frontiers in Aging Neuroscience 1, 0, 2013
PcoE–a metal sponge expressed to the periplasm of copper resistance E. coli. Implication of its function role in copper resistance
M Zimmermann, S Udagedara, CM Sze, TM Ryan, GJ Howlett, Z Xiao, ...
Journal of Inorganic Biochemistry 115, 186-197, 2012
An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis
TM Ryan, J Trewhella, JM Murphy, JR Keown, L Casey, FG Pearce, ...
Journal of applied crystallography 51 (1), 97-111, 2018
The effect of paraformaldehyde fixation and sucrose cryoprotection on metal concentration in murine neurological tissue
DJ Hare, JL George, L Bray, I Volitakis, A Vais, TM Ryan, RA Cherny, ...
Journal of Analytical Atomic Spectrometry 29 (3), 565-570, 2014
Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass …
DJ Hare, A Grubman, TM Ryan, A Lothian, JR Liddell, R Grimm, ...
Metallomics 5 (12), 1656-1662, 2013
Small amphipathic molecules modulate the secondary structure and amyloid fibril forming kinetics of the Alzheimer's disease peptide Aβ1-42
TM Ryan, A Friedhuber, M Lind, GJ Howlett, CL Masters, BR Roberts
Journal of Biological Chemistry, 2012
Domain organization of the monomeric form of the Tom70 mitochondrial import receptor
RD Mills, J Trewhella, TW Qiu, T Welte, TM Ryan, T Hanley, RB Knott, ...
Journal of molecular biology 388 (5), 1043-1058, 2009
Fluorescence detection of a lipid-induced tetrameric intermediate in amyloid fibril formation by apolipoprotein C-II
TM Ryan, GJ Howlett, MF Bailey
Journal of biological chemistry 283 (50), 35118-35128, 2008
Effects of polysaccharide charge pattern on the microstructures of β-lactoglobulin-pectin complex coacervates, studied by SAXS and SANS
AY Xu, LD Melton, TM Ryan, JP Mata, A Rekas, MAK Williams, ...
Food Hydrocolloids 77, 952-963, 2018
High-affinity amphipathic modulators of amyloid fibril nucleation and elongation
TM Ryan, MDW Griffin, CL Teoh, J Ooi, GJ Howlett
Journal of molecular biology 406 (3), 416-429, 2011
Sedimentation velocity analysis of amyloid oligomers and fibrils using fluorescence detection
YF Mok, TM Ryan, S Yang, DM Hatters, GJ Howlett, MDW Griffin
Methods 54 (1), 67-75, 2011
The acute phase protein lactoferrin is a key feature of Alzheimer’s disease and predictor of Aβ burden through induction of APP amyloidogenic processing
A Tsatsanis, AN McCorkindale, BX Wong, E Patrick, TM Ryan, RW Evans, ...
Molecular psychiatry 26 (10), 5516-5531, 2021
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