| Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility Australo-Anglo-American Spondyloarthritis Consortium (TASC), ... Nature genetics 43 (8), 761-767, 2011 | 917 | 2011 |
| Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming G Kochan, T Krojer, D Harvey, R Fischer, L Chen, M Vollmar, F von Delft, ... Proceedings of the National Academy of Sciences 108 (19), 7745-7750, 2011 | 263 | 2011 |
| Role of severe acute respiratory syndrome coronavirus viroporins E, 3a, and 8a in replication and pathogenesis C Castaño-Rodriguez, JM Honrubia, J Gutiérrez-Álvarez, ML DeDiego, ... MBio 9 (3), e02325-17, 2018 | 236* | 2018 |
| PDL1 signals through conserved sequence motifs to overcome interferon-mediated cytotoxicity M Gato-Cañas, M Zuazo, H Arasanz, M Ibañez-Vea, L Lorenzo, ... Cell reports 20 (8), 1818-1829, 2017 | 228 | 2017 |
| PD1 signal transduction pathways in T cells H Arasanz, M Gato-Cañas, M Zuazo, M Ibañez-Vea, K Breckpot, ... Oncotarget 8 (31), 51936, 2017 | 222 | 2017 |
| The intracellular signalosome of PD-L1 in cancer cells D Escors, M Gato-Cañas, M Zuazo, H Arasanz, MJ García-Granda, R Vera, ... Signal transduction and targeted therapy 3 (1), 26, 2018 | 192 | 2018 |
| Role of non-classical MHC class I molecules in cancer immunosuppression G Kochan, D Escors, K Breckpot, D Guerrero-Setas Oncoimmunology 2 (11), e26491, 2013 | 164 | 2013 |
| Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases NR Rose, ECY Woon, A Tumber, LJ Walport, R Chowdhury, XS Li, ... Journal of medicinal chemistry 55 (14), 6639-6643, 2012 | 140 | 2012 |
| Functional systemic CD 4 immunity is required for clinical responses to PD‐L1/PD‐1 blockade therapy M Zuazo, H Arasanz, G Fernández‐Hinojal, MJ García‐Granda, M Gato, ... EMBO molecular medicine 11 (7), e10293, 2019 | 139 | 2019 |
| Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation DS Froese, G Kochan, JRC Muniz, X Wu, C Gileadi, E Ugochukwu, ... Journal of Biological Chemistry 285 (49), 38204-38213, 2010 | 125 | 2010 |
| Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A G Kochan, ES Pilka, F von Delft, U Oppermann, WW Yue Journal of molecular biology 388 (5), 997-1008, 2009 | 117 | 2009 |
| Crystal structure of the 2-oxoglutarate-and Fe (II)-dependent lysyl hydroxylase JMJD6 M Mantri, T Krojer, EA Bagg, CJ Webby, DS Butler, G Kochan, ... Journal of molecular biology 401 (2), 211-222, 2010 | 99 | 2010 |
| Structural and mechanistic studies on γ-butyrobetaine hydroxylase IKH Leung, TJ Krojer, GT Kochan, L Henry, F von Delft, TDW Claridge, ... Chemistry & biology 17 (12), 1316-1324, 2010 | 91 | 2010 |
| PD-L1 expression in systemic immune cell populations as a potential predictive biomarker of responses to PD-L1/PD-1 blockade therapy in lung cancer A Bocanegra, G Fernandez-Hinojal, M Zuazo-Ibarra, H Arasanz, ... International journal of molecular sciences 20 (7), 1631, 2019 | 73 | 2019 |
| A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice T Liechtenstein, N Perez-Janices, M Gato, F Caliendo, G Kochan, ... Oncotarget 5 (17), 7843, 2014 | 69 | 2014 |
| MVA-LACK as a safe and efficient vector for vaccination against leishmaniasis E Pérez-Jiménez, G Kochan, MM Gherardi, M Esteban Microbes and infection 8 (3), 810-822, 2006 | 66 | 2006 |
| Structural basis for substrate specificity in human monomeric carbonyl reductases ES Pilka, FH Niesen, WH Lee, Y El-Hawari, JE Dunford, G Kochan, ... PLoS One 4 (10), e7113, 2009 | 64 | 2009 |
| Understanding LAG-3 signaling L Chocarro, E Blanco, M Zuazo, H Arasanz, A Bocanegra, ... International journal of molecular sciences 22 (10), 5282, 2021 | 60 | 2021 |
| Early detection of hyperprogressive disease in non-small cell lung cancer by monitoring of systemic T cell dynamics H Arasanz, M Zuazo, A Bocanegra, M Gato, M Martínez-Aguillo, I Morilla, ... Cancers 12 (2), 344, 2020 | 58 | 2020 |
| Crystal structure of the secretory isozyme of mammalian carbonic anhydrases CA VI: implications for biological assembly and inhibitor development ES Pilka, G Kochan, U Oppermann, WW Yue Biochemical and Biophysical Research Communications 419 (3), 485-489, 2012 | 55 | 2012 |
David Escors Murugarren (ORCID:000...Principal Investigator, NavarraBiomed, University College LondonBestätigte E-Mail-Adresse bei ucl.ac.uk
