Rhett Kovall
Rhett Kovall
Associate Professor, University of Cincinnati College of Medicine
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Zitiert von
Zitiert von
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA
JJ Wilson, RA Kovall
Cell 124 (5), 985-996, 2006
The canonical Notch signaling pathway: structural and biochemical insights into shape, sugar, and force
RA Kovall, B Gebelein, D Sprinzak, R Kopan
Developmental cell 41 (3), 228-241, 2017
Toroidal structure of λ-exonuclease
R Kovall, BW Matthews
Science 277 (5333), 1824-1827, 1997
Mechanistic insights into Notch receptor signaling from structural and biochemical studies
RA Kovall, SC Blacklow
Current topics in developmental biology 92, 31-71, 2010
Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA
RA Kovall, WA Hendrickson
The EMBO journal 23 (17), 3441-3451, 2004
More complicated than it looks: assembly of Notch pathway transcription complexes
RA Kovall
Oncogene 27 (38), 5099-5109, 2008
Crystal structure of human α-tocopherol transfer protein bound to its ligand: implications for ataxia with vitamin E deficiency
KC Min, RA Kovall, WA Hendrickson
Proceedings of the National Academy of Sciences 100 (25), 14713-14718, 2003
Type II restriction endonucleases: structural, functional and evolutionary relationships
RA Kovall, BW Matthews
Current opinion in chemical biology 3 (5), 578-583, 1999
Structures of CSL, Notch and Mastermind proteins: piecing together an active transcription complex
RA Kovall
Current opinion in structural biology 17 (1), 117-127, 2007
Notch signaling: genetics and structure
I Greenwald, R Kovall
WormBook: The Online Review of C. elegans Biology [Internet], 2018
RAM-induced allostery facilitates assembly of a notch pathway active transcription complex
DR Friedmann, JJ Wilson, RA Kovall
Journal of biological chemistry 283 (21), 14781-14791, 2008
Structural, functional, and evolutionary relationships between λ-exonuclease and the type II restriction endonucleases
RA Kovall, BW Matthews
Proceedings of the National Academy of Sciences 95 (14), 7893-7897, 1998
Activation of the Notch signaling pathway in vivo elicits changes in CSL nuclear dynamics
MJ Gomez-Lamarca, J Falo-Sanjuan, R Stojnic, SA Rehman, L Muresan, ...
Developmental Cell 44 (5), 611-623. e7, 2018
A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes
F Oswald, P Rodriguez, BD Giaimo, ZA Antonello, L Mira, G Mittler, ...
Nucleic acids research 44 (10), 4703-4720, 2016
Structure and function of the CSL-KyoT2 corepressor complex: a negative regulator of Notch signaling
KJ Collins, Z Yuan, RA Kovall
Structure 22 (1), 70-81, 2014
Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexes
BD VanderWielen, Z Yuan, DR Friedmann, RA Kovall
Journal of Biological Chemistry 286 (17), 14892-14902, 2011
RBPJ/CBF 1 interacts with L3 MBTL 3/MBT 1 to promote repression of Notch signaling via histone demethylase KDM 1A/LSD 1
T Xu, SS Park, BD Giaimo, D Hall, F Ferrante, DM Ho, K Hori, L Anhezini, ...
The EMBO journal 36 (21), 3232-3249, 2017
Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster
Z Yuan, H Praxenthaler, N Tabaja, R Torella, A Preiss, D Maier, RA Kovall
PLoS biology 14 (7), e1002509, 2016
Thermodynamic and structural insights into CSL‐DNA complexes
DR Friedmann, RA Kovall
Protein Science 19 (1), 34-46, 2010
Catalase (KatA) plays a role in protection against anaerobic nitric oxide in Pseudomonas aeruginosa
S Su, W Panmanee, JJ Wilson, HK Mahtani, Q Li, BD VanderWielen, ...
PLoS One 9 (3), e91813, 2014
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