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Michael L. Whitfield, PhD
Michael L. Whitfield, PhD
Chair and Professor of Biomedical Data Science, Geisel School of Medicine at Dartmouth
Bestätigte E-Mail-Adresse bei dartmouth.edu
Titel
Zitiert von
Zitiert von
Jahr
Identification of genes periodically expressed in the human cell cycle and their expression in tumors
ML Whitfield, G Sherlock, AJ Saldanha, JI Murray, CA Ball, KE Alexander, ...
Molecular biology of the cell 13 (6), 1977-2000, 2002
18922002
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
T Hung, Y Wang, MF Lin, AK Koegel, Y Kotake, GD Grant, HM Horlings, ...
Nature genetics 43 (7), 621-629, 2011
13802011
Common markers of proliferation
ML Whitfield, LK George, GD Grant, CM Perou
Nature Reviews Cancer 6 (2), 99-106, 2006
6882006
Systemic and cell type-specific gene expression patterns in scleroderma skin
ML Whitfield, DR Finlay, JI Murray, OG Troyanskaya, JT Chi, ...
Proceedings of the National Academy of Sciences 100 (21), 12319-12324, 2003
5182003
Shared and distinct mechanisms of fibrosis
JHW Distler, AH Györfi, M Ramanujam, ML Whitfield, M Königshoff, ...
Nature Reviews Rheumatology 15 (12), 705-730, 2019
4682019
Molecular subsets in the gene expression signatures of scleroderma skin
A Milano, SA Pendergrass, JL Sargent, LK George, TH McCalmont, ...
PloS one 3 (7), e2696, 2008
4432008
The pathogenesis of systemic sclerosis
TR Katsumoto, ML Whitfield, MK Connolly
Annual Review of Pathology: Mechanisms of Disease 6 (1), 509-537, 2011
4022011
Diverse and specific gene expression responses to stresses in cultured human cells
JI Murray, ML Whitfield, ND Trinklein, RM Myers, PO Brown, D Botstein
Molecular biology of the cell 15 (5), 2361-2374, 2004
3842004
Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients
LM Rice, CM Padilla, SR McLaughlin, A Mathes, J Ziemek, S Goummih, ...
The Journal of clinical investigation 125 (7), 2795-2807, 2015
3782015
Myofibroblasts in murine cutaneous fibrosis originate from adiponectin‐positive intradermal progenitors
RG Marangoni, BD Korman, J Wei, TA Wood, LV Graham, ML Whitfield, ...
Arthritis & rheumatology 67 (4), 1062-1073, 2015
3422015
Stem-loop binding protein, the protein that binds the 3′ end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms
ML Whitfield, LX Zheng, A Baldwin, T Ohta, MM Hurt, WF Marzluff
Molecular and cellular biology, 2000
3192000
The protein that binds the 3'end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing.
ZF Wang, ML Whitfield, TC Ingledue, Z Dominski, WF Marzluff
Genes & development 10 (23), 3028-3040, 1996
3131996
Wnt/β‐catenin signaling is hyperactivated in systemic sclerosis and induces Smad‐dependent fibrotic responses in mesenchymal cells
J Wei, F Fang, AP Lam, JL Sargent, E Hamburg, ME Hinchcliff, CJ Gottardi, ...
Arthritis & Rheumatism 64 (8), 2734-2745, 2012
2612012
Abatacept in early diffuse cutaneous systemic sclerosis: results of a phase II investigator‐initiated, multicenter, double‐blind, randomized, placebo‐controlled trial
D Khanna, C Spino, S Johnson, L Chung, ML Whitfield, CP Denton, ...
Arthritis & rheumatology 72 (1), 125-136, 2020
2142020
PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis
J Wei, AK Ghosh, JL Sargent, K Komura, M Wu, QQ Huang, M Jain, ...
PloS one 5 (11), e13778, 2010
2132010
Identification of cell cycle–regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors
GD Grant, L Brooks 3rd, X Zhang, JM Mahoney, V Martyanov, TA Wood, ...
Molecular biology of the cell 24 (23), 3634-3650, 2013
1992013
Universal Reference RNA as a standard for microarray experiments
N Novoradovskaya, ML Whitfield, LS Basehore, A Novoradovsky, ...
BMC genomics 5, 1-13, 2004
1992004
Molecular signatures in skin associated with clinical improvement during mycophenolate treatment in systemic sclerosis
M Hinchcliff, CC Huang, TA Wood, JM Mahoney, V Martyanov, ...
Journal of Investigative Dermatology 133 (8), 1979-1989, 2013
1912013
Intrinsic gene expression subsets of diffuse cutaneous systemic sclerosis are stable in serial skin biopsies
SA Pendergrass, R Lemaire, IP Francis, JM Mahoney, R Lafyatis, ...
Journal of Investigative Dermatology 132 (5), 1363-1373, 2012
1862012
A TGFβ-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity
JL Sargent, A Milano, S Bhattacharyya, J Varga, MK Connolly, HY Chang, ...
Journal of Investigative Dermatology 130 (3), 694-705, 2010
1822010
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