| Presence of SARS-Coronavirus-2 RNA in sewage and correlation with reported COVID-19 prevalence in the early stage of the epidemic in the Netherlands G Medema, L Heijnen, G Elsinga, R Italiaander, A Brouwer Environmental science & technology letters 7 (7), 511-516, 2020 | 1747 | 2020 |
| Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana K Mayer, C Schüller, R Wambutt, G Murphy, G Volckaert, T Pohl, ... Nature 402 (6763), 769-777, 1999 | 486 | 1999 |
| The tomato Mi-1 gene confers resistance to both root-knot nematodes and potato aphids T Jesse, J Wijbrandi, L Heinen, R Hogers, A Frijters, J Groenendijk, ... Nature biotechnology 16 (13), 1365-1369, 1998 | 429 | 1998 |
| Implementation of environmental surveillance for SARS-CoV-2 virus to support public health decisions: opportunities and challenges G Medema, F Been, L Heijnen, S Petterson Current opinion in environmental science & health 17, 49-71, 2020 | 302 | 2020 |
| Monitoring SARS-CoV-2 circulation and diversity through community wastewater sequencing, the Netherlands and Belgium R Izquierdo-Lara, G Elsinga, L Heijnen, BBO Munnink, ... Emerging infectious diseases 27 (5), 1405, 2021 | 198 | 2021 |
| Quantitative detection of E. coli, E. coli O157 and other shiga toxin producing E. coli in water samples using a culture method combined with real-time PCR L Heijnen, G Medema Journal of Water and Health 4 (4), 487-498, 2006 | 172 | 2006 |
| Direct comparison of selected methods for genetic categorisation of Cryptosporidium parvum and Cryptosporidium hominis species RM Chalmers, C Ferguson, S Cacciò, RB Gasser, YGA El-Osta, L Heijnen, ... International Journal for Parasitology 35 (4), 397-410, 2005 | 160 | 2005 |
| Intracellular transport of recombinant coronavirus spike proteins: implications for virus assembly H Vennema, L Heijnen, A Zijderveld, MC Horzinek, WJ Spaan Journal of virology 64 (1), 339-346, 1990 | 149 | 1990 |
| Escherichia coli O157: H7 in drinking water from private water supplies in the Netherlands FM Schets, M During, R Italiaander, L Heijnen, SA Rutjes, ... Water research 39 (18), 4485-4493, 2005 | 148 | 2005 |
| Surveillance of influenza A and the pandemic influenza A (H1N1) 2009 in sewage and surface water in the Netherlands L Heijnen, G Medema Journal of water and health 9 (3), 434-442, 2011 | 143 | 2011 |
| Mutational analysis of the murine coronavirus spike protein: effect on cell-to-cell fusion ECW BOS, LEO HEIJNEN, W LUYTJES, WJM SPAAN Virology 214 (2), 453-463, 1995 | 123 | 1995 |
| Droplet digital RT-PCR to detect SARS-CoV-2 signature mutations of variants of concern in wastewater L Heijnen, G Elsinga, M de Graaf, R Molenkamp, MPG Koopmans, ... Science of The Total Environment 799, 149456, 2021 | 108 | 2021 |
| Homologous RNA recombination allows efficient introduction of site-specific mutations into the genome of coronavirus MHV-A59 via synthetic co-replicating RNAs RG van der Most, L Heijnen, WJM Spaan, RJ de Groot Nucleic acids research 20 (13), 3375-3381, 1992 | 88 | 1992 |
| Method for generating oligonucleotides, in particular for the detection of amplified restriction fragments obtained using AFLP® MJT Van Eijk, RCJ Hogers, L Heijnen US Patent 7,166,429, 2007 | 86 | 2007 |
| Method for rapid detection of viable Escherichia coli in water using real-time NASBA L Heijnen, G Medema Water research 43 (12), 3124-3132, 2009 | 81 | 2009 |
| Prevalence and circulation patterns of SARS-CoV-2 variants in European sewage mirror clinical data of 54 European cities S Agrawal, L Orschler, S Schubert, K Zachmann, L Heijnen, S Tavazzi, ... Water research 214, 118162, 2022 | 56 | 2022 |
| Enhancement of the vaccinia virus/phage T7 RNA polymerase expression system using encephalomyocarditis virus 5'-untranslated region sequences H Vennema, R Rijnbrand, L Heijnen, MC Horzinek, WJM Spaan Gene 108 (2), 201-209, 1991 | 53 | 1991 |
| A novel glycoprotein of feline infectious peritonitis coronavirus contains a KDEL-like endoplasmic reticulum retention signal H Vennema, L Heijnen, PJ Rottier, MC Horzinek, WJ Spaan Journal of virology 66 (8), 4951-4956, 1992 | 45 | 1992 |
| Normalisation of SARS-CoV-2 concentrations in wastewater: The use of flow, electrical conductivity and crAssphage J Langeveld, R Schilperoort, L Heijnen, G Elsinga, CEM Schapendonk, ... Science of the Total Environment 865, 161196, 2023 | 38 | 2023 |
| Mobility and redox transformation of arsenic during treatment of artificially recharged groundwater for drinking water production A Ahmad, L Heijnen, L de Waal, F Battaglia-Brunet, W Oorthuizen, ... Water Research 178, 115826, 2020 | 38 | 2020 |
