Extensive variation in chromatin states across humans M Kasowski, S Kyriazopoulou-Panagiotopoulou, F Grubert, JB Zaugg, ... Science 342 (6159), 750-752, 2013 | 409 | 2013 |
Variation and genetic control of protein abundance in humans L Wu, SI Candille, Y Choi, D Xie, L Jiang, J Li-Pook-Than, H Tang, ... Nature 499 (7456), 79-82, 2013 | 389 | 2013 |
Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species D Xie, CC Chen, LM Ptaszek, S Xiao, X Cao, F Fang, HH Ng, HA Lewin, ... Genome research 20 (6), 804-815, 2010 | 254 | 2010 |
5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages CX Song, S Yin, L Ma, A Wheeler, Y Chen, Y Zhang, B Liu, J Xiong, ... Cell research 27 (10), 1231-1242, 2017 | 244 | 2017 |
Whole-genome haplotyping using long reads and statistical methods V Kuleshov, D Xie, R Chen, D Pushkarev, Z Ma, T Blauwkamp, M Kertesz, ... Nature biotechnology 32 (3), 261-266, 2014 | 224 | 2014 |
Comparative analysis of regulatory information and circuits across distant species AP Boyle, CL Araya, C Brdlik, P Cayting, C Cheng, Y Cheng, K Gardner, ... Nature 512 (7515), 453-456, 2014 | 222 | 2014 |
Comparative Epigenomic Annotation of Regulatory DNA S Xiao, D Xie, X Cao, P Yu, X Xing, CC Chen, M Musselman, M Xie, ... Cell 149 (6), 1381-1392, 2012 | 214 | 2012 |
LOCSVMPSI: a web server for subcellular localization of eukaryotic proteins using SVM and profile of PSI-BLAST D Xie, A Li, M Wang, Z Fan, H Feng Nucleic acids research 33 (suppl_2), W105-W110, 2005 | 200 | 2005 |
Dynamic trans-acting factor colocalization in human cells D Xie, AP Boyle, L Wu, J Zhai, T Kawli, M Snyder Cell 155 (3), 713-724, 2013 | 156 | 2013 |
Regulatory analysis of the C. elegans genome with spatiotemporal resolution CL Araya, T Kawli, A Kundaje, L Jiang, B Wu, D Vafeados, R Terrell, ... Nature 512 (7515), 400-405, 2014 | 122 | 2014 |
Longitudinal personal DNA methylome dynamics in a human with a chronic condition R Chen, L Xia, K Tu, M Duan, K Kukurba, J Li-Pook-Than, D Xie, ... Nature medicine 24 (12), 1930-1939, 2018 | 57 | 2018 |
Cross-species de novo identification of cis-regulatory modules with GibbsModule: application to gene regulation in embryonic stem cells D Xie, J Cai, NY Chia, HH Ng, S Zhong Genome Research 18 (8), 1325-1335, 2008 | 39 | 2008 |
Modeling co-expression across species for complex traits: insights to the difference of human and mouse embryonic stem cells J Cai, D Xie, Z Fan, H Chipperfield, J Marden, WH Wong, S Zhong PLoS computational biology 6 (3), e1000707, 2010 | 38 | 2010 |
Transcriptomic and open chromatin atlas of high-resolution anatomical regions in the rhesus macaque brain S Yin, K Lu, T Tan, J Tang, J Wei, X Liu, X Hu, H Wan, W Huang, Y Fan, ... Nature communications 11 (1), 474, 2020 | 36 | 2020 |
Integrated epigenetic biomarkers in circulating cell-free DNA as a robust classifier for pancreatic cancer F Cao, A Wei, X Hu, Y He, J Zhang, L Xia, K Tu, J Yuan, Z Guo, H Liu, ... Clinical epigenetics 12, 1-14, 2020 | 34 | 2020 |
Understanding variation in transcription factor binding by modeling transcription factor genome-epigenome interactions CC Chen, S Xiao, D Xie, X Cao, CX Song, T Wang, C He, S Zhong PLoS computational biology 9 (12), e1003367, 2013 | 29 | 2013 |
Subtypes of schizophrenia identified by multi-omic measures associated with dysregulated immune function C Luo, XN Pi, N Hu, X Wang, Y Xiao, S Li, JA Sweeney, JR Bishop, ... Molecular psychiatry 26 (11), 6926-6936, 2021 | 28 | 2021 |
The open chromatin landscape of non–small cell lung carcinoma Z Wang, K Tu, L Xia, K Luo, W Luo, J Tang, K Lu, X Hu, Y He, W Qiao, ... Cancer research 79 (19), 4840-4854, 2019 | 25 | 2019 |
Dissecting early differentially expressed genes in a mixture of differentiating embryonic stem cells F Hong, F Fang, X He, X Cao, H Chipperfield, D Xie, WH Wong, HH Ng, ... PLoS computational biology 5 (12), e1000607, 2009 | 24 | 2009 |
Liquid biopsy by combining 5-hydroxymethylcytosine signatures of plasma cell-free DNA and protein biomarkers for diagnosis and prognosis of hepatocellular carcinoma Z Cai, J Zhang, Y He, L Xia, X Dong, G Chen, Y Zhou, X Hu, S Zhong, ... ESMO open 6 (1), 100021, 2021 | 19 | 2021 |