| A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma HV Erkizan, Y Kong, M Merchant, S Schlottmann, JS Barber-Rotenberg, ... Nature medicine 15 (7), 750-756, 2009 | 478 | 2009 |
| The molecular basis of vitamin D receptor and β-catenin crossregulation S Shah, MN Islam, S Dakshanamurthy, I Rizvi, M Rao, R Herrell, G Zinser, ... Molecular cell 21 (6), 799-809, 2006 | 302 | 2006 |
| A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors I Petrini, PS Meltzer, IK Kim, M Lucchi, KS Park, G Fontanini, J Gao, ... Nature genetics 46 (8), 844-849, 2014 | 248 | 2014 |
| Covalent binding to tubulin by isothiocyanates: a mechanism of cell growth arrest and apoptosis L Mi, Z Xiao, BL Hood, S Dakshanamurthy, X Wang, S Govind, ... Journal of biological chemistry 283 (32), 22136-22146, 2008 | 247 | 2008 |
| Asymmetric synthesis of 2, 3-dihydro-2-arylquinazolin-4-ones: methodology and application to a potent fluorescent tubulin inhibitor with anticancer activity GM Chinigo, M Paige, S Grindrod, E Hamel, S Dakshanamurthy, ... Journal of medicinal chemistry 51 (15), 4620-4631, 2008 | 241 | 2008 |
| Predicting new indications for approved drugs using a proteochemometric method S Dakshanamurthy, NT Issa, S Assefnia, A Seshasayee, OJ Peters, ... Journal of medicinal chemistry 55 (15), 6832-6848, 2012 | 182 | 2012 |
| Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells G Bulut, SH Hong, K Chen, EM Beauchamp, S Rahim, GW Kosturko, ... Oncogene 31 (3), 269-281, 2012 | 181 | 2012 |
| Mechanisms of unphosphorylated STAT3 transcription factor binding to DNA OA Timofeeva, S Chasovskikh, I Lonskaya, NI Tarasova, L Khavrutskii, ... Journal of Biological Chemistry 287 (17), 14192-14200, 2012 | 176 | 2012 |
| Machine and deep learning approaches for cancer drug repurposing NT Issa, V Stathias, S Schürer, S Dakshanamurthy Seminars in cancer biology 68, 132-142, 2021 | 153 | 2021 |
| Cancer preventive isothiocyanates induce selective degradation of cellular α-and β-tubulins by proteasomes L Mi, N Gan, A Cheema, S Dakshanamurthy, X Wang, DCH Yang, ... Journal of biological chemistry 284 (25), 17039-17051, 2009 | 138 | 2009 |
| Big data: the next frontier for innovation in therapeutics and healthcare NT Issa, SW Byers, S Dakshanamurthy Expert review of clinical pharmacology 7 (3), 293-298, 2014 | 110 | 2014 |
| Drug metabolism in preclinical drug development: a survey of the discovery process, toxicology, and computational tools N T Issa, H Wathieu, A Ojo, S W Byers, S Dakshanamurthy Current drug metabolism 18 (6), 556-565, 2017 | 108 | 2017 |
| Allelic variation in KIR2DL3 generates a KIR2DL2-like receptor with increased binding to its HLA-C ligand WR Frazier, N Steiner, L Hou, S Dakshanamurthy, CK Hurley The Journal of Immunology 190 (12), 6198-6208, 2013 | 84 | 2013 |
| Dramatically reduced surface expression of NK cell receptor KIR2DS3 is attributed to multiple residues throughout the molecule CJ VandenBussche, TJ Mulrooney, WR Frazier, S Dakshanamurthy, ... Genes & Immunity 10 (2), 162-173, 2009 | 81 | 2009 |
| Tumor suppressor RARRES1 interacts with cytoplasmic carboxypeptidase AGBL2 to regulate the α-tubulin tyrosination cycle ZJ Sahab, MD Hall, Y Me Sung, S Dakshanamurthy, Y Ji, D Kumar, ... Cancer research 71 (4), 1219-1228, 2011 | 79 | 2011 |
| Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells AS Oh, JT Lahusen, CD Chien, MP Fereshteh, X Zhang, ... Molecular and cellular biology 28 (21), 6580-6593, 2008 | 78 | 2008 |
| Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies S Assefnia, S Dakshanamurthy, JMG Auvil, C Hampel, PZ Anastasiadis, ... Oncotarget 5 (6), 1458, 2014 | 75 | 2014 |
| G-DOC: a systems medicine platform for personalized oncology S Madhavan, Y Gusev, M Harris, DM Tanenbaum, R Gauba, ... Neoplasia 13 (9), 771-783, 2011 | 75 | 2011 |
| Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK) AN Shajahan, ZC Dobbin, FE Hickman, S Dakshanamurthy, R Clarke Journal of Biological Chemistry 287 (21), 17682-17692, 2012 | 69 | 2012 |
| The role of calcium in the activation of estrogen receptor-alpha SD Divekar, GB Storchan, K Sperle, DJ Veselik, E Johnson, ... Cancer research 71 (5), 1658-1668, 2011 | 64 | 2011 |
