| Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells JD Grevet, X Lan, N Hamagami, CR Edwards, L Sankaranarayanan, X Ji, ... Science 361 (6399), 285-290, 2018 | 151 | 2018 |
| ATXN7L3 and ENY2 coordinate activity of multiple H2B deubiquitinases important for cellular proliferation and tumor growth BS Atanassov, RD Mohan, X Lan, X Kuang, Y Lu, K Lin, E McIvor, W Li, ... Molecular cell 62 (4), 558-571, 2016 | 141 | 2016 |
| ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression X Lan, R Ren, R Feng, LC Ly, Y Lan, Z Zhang, N Aboreden, K Qin, ... Molecular cell 81 (2), 239-254. e8, 2021 | 63 | 2021 |
| The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression P Huang, SA Peslak, X Lan, E Khandros, JA Yano, M Sharma, CA Keller, ... Blood, The Journal of the American Society of Hematology 135 (24), 2121-2132, 2020 | 57 | 2020 |
| USP44 is an integral component of N-CoR that contributes to gene repression by deubiquitinating histone H2B X Lan, BS Atanassov, W Li, Y Zhang, L Florens, RD Mohan, PJ Galardy, ... Cell reports 17 (9), 2382-2393, 2016 | 53 | 2016 |
| Poly (Q) expansions in ATXN7 affect solubility but not activity of the SAGA deubiquitinating module X Lan, E Koutelou, AC Schibler, YC Chen, PA Grant, SYR Dent Molecular and cellular biology, 2015 | 38 | 2015 |
| The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells X Lan, E Khandros, P Huang, SA Peslak, SK Bhardwaj, JD Grevet, ... Blood Advances 3 (10), 1586-1597, 2019 | 33 | 2019 |
| HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription P Huang, SA Peslak, R Ren, E Khandros, K Qin, CA Keller, B Giardine, ... Nature genetics 54 (9), 1417-1426, 2022 | 25 | 2022 |
| Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells K Qin, P Huang, R Feng, CA Keller, SA Peslak, E Khandros, MS Saari, ... Nature genetics 54 (6), 874-884, 2022 | 24 | 2022 |
| Cytoplasmic ATXN7L3B interferes with nuclear functions of the SAGA deubiquitinase module W Li, BS Atanassov, X Lan, RD Mohan, SK Swanson, AT Farria, L Florens, ... Molecular and cellular biology 36 (22), 2855-2866, 2016 | 22 | 2016 |
| Comparative analysis of duplicated sox21 genes in zebrafish X Lan, L Wen, K Li, X Liu, B Luo, F Chen, D Xie, H Kung Development, growth & differentiation 53 (3), 347-356, 2011 | 20 | 2011 |
| HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation SA Peslak, E Khandros, P Huang, X Lan, CL Geronimo, JD Grevet, ... Blood Advances 4 (18), 4560-4572, 2020 | 18 | 2020 |
| Molecular basis of polycomb group protein–mediated fetal hemoglobin repression K Qin, X Lan, P Huang, MS Saari, E Khandros, CA Keller, B Giardine, ... Blood, The Journal of the American Society of Hematology 141 (22), 2756-2770, 2023 | 7 | 2023 |
| Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410–DNA interaction using small angle X-ray scattering G Kaur, R Ren, M Hammel, JR Horton, J Yang, Y Cao, C He, F Lan, X Lan, ... Nucleic acids research 51 (4), 1674-1686, 2023 | 4 | 2023 |
| Author Correction: HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription P Huang, SA Peslak, R Ren, E Khandros, K Qin, CA Keller, B Giardine, ... Nature Genetics 55 (9), 1608-1608, 2023 | 1 | 2023 |
| Heme-Regulated Inhibitor (HRI) Activates Transcription Factor ATF4 to Promote BCL11A Transcription and Fetal Hemoglobin Silencing P Huang, SA Peslak, X Lan, E Khandros, M Sharma, K Qin, CA Keller, ... Blood 134, 814, 2019 | 1 | 2019 |
| Domain-focused CRISPR-Cas9 screen identifies the E3 ubiquitin ligase substrate adaptor protein SPOP as a novel repressor of fetal hemoglobin X Lan, E Khandros, JD Grevet, SA Peslak, S Bhardwaj, CA Keller, ... Blood 132 (Supplement 1), 414-414, 2018 | 1 | 2018 |
| Mechanistic dissection of the CHD4 enhancers reveals cooperative functions among the homotypic ZNF410 clustered motifs S Xu, R Ren, C Peng, H Lu, LC Ly, M Crossley, B Xu, X Cheng, GA Blobel, ... bioRxiv, 2024.02. 24.581901, 2024 | | 2024 |
| Compositions and methods for hemoglobin production G Blobel, X Lan, J Shi US Patent App. 18/015,800, 2023 | | 2023 |
| Mechanisms of Polycomb Group Protein-Mediated Fetal Hemoglobin Silencing K Qin, P Huang, X Lan, MS Saari, E Khandros, OY Abdulmalik, CA Keller, ... Blood 140 (Supplement 1), 5382-5383, 2022 | | 2022 |
