Karthik A. Jagadeesh
Karthik A. Jagadeesh
Postdoctoral Associate, Broad Institute
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Zitiert von
Zitiert von
Intra-and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
CS Smillie, M Biton, J Ordovas-Montanes, KM Sullivan, G Burgin, ...
Cell 178 (3), 714-730. e22, 2019
M-CAP eliminates a majority of variants of uncertain significance in clinical exomes at high sensitivity
KA Jagadeesh, AM Wenger, MJ Berger, H Guturu, PD Stenson, ...
Nature genetics 48 (12), 1581-1586, 2016
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ...
Nature, 1-8, 2021
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ...
Nature medicine, 1-14, 2021
Emergent high fatality lung disease in systemic juvenile arthritis
VE Saper, G Chen, GH Deutsch, RP Guillerman, J Birgmeier, ...
Annals of the Rheumatic Diseases 78 (12), 1722-1731, 2019
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment
WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ...
Nature Genetics 54 (8), 1178-1191, 2022
Deriving genomic diagnoses without revealing patient genomes
KA Jagadeesh, DJ Wu, JA Birgmeier, D Boneh, G Bejerano
Science 357 (6352), 692-695, 2017
Severe autoinflammation in 4 patients with C-terminal variants in cell division control protein 42 homolog (CDC42) successfully treated with IL-1β inhibition
Y Gernez, AA de Jesus, H Alsaleem, C Macaubas, A Roy, D Lovell, ...
Journal of Allergy and Clinical Immunology 144 (4), 1122-1125. e6, 2019
Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics
KA Jagadeesh, KK Dey, DT Montoro, R Mohan, S Gazal, JM Engreitz, ...
Nature Genetics 54 (10), 1479-1492, 2022
AMELIE speeds Mendelian diagnosis by matching patient phenotype and genotype to primary literature
J Birgmeier, M Haeussler, CA Deisseroth, EH Steinberg, KA Jagadeesh, ...
Science translational medicine 12 (544), eaau9113, 2020
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity
S Gazal, O Weissbrod, F Hormozdiari, KK Dey, J Nasser, KA Jagadeesh, ...
Nature genetics 54 (6), 827-836, 2022
Polygenic architecture of rare coding variation across 394,783 exomes
DJ Weiner, A Nadig, KA Jagadeesh, KK Dey, BM Neale, EB Robinson, ...
Nature 614 (7948), 492-499, 2023
Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data
MJ Zhang, K Hou, KK Dey, S Sakaue, KA Jagadeesh, K Weinand, ...
Nature genetics 54 (10), 1572-1580, 2022
S-CAP extends pathogenicity prediction to genetic variants that affect RNA splicing
KA Jagadeesh, JM Paggi, JS Ye, PD Stenson, DN Cooper, JA Bernstein, ...
Nature genetics 51 (4), 755-763, 2019
Phrank measures phenotype sets similarity to greatly improve Mendelian diagnostic disease prioritization
KA Jagadeesh, J Birgmeier, H Guturu, CA Deisseroth, AM Wenger, ...
Genetics in Medicine, 2018
Convolutional neural networks for fashion classification and object detection
B Lao, K Jagadeesh
CCCV 2015 Comput. Vis 546, 120-129, 2015
SAIGE-GENE+ improves the efficiency and accuracy of set-based rare variant association tests
W Zhou, W Bi, Z Zhao, KK Dey, KA Jagadeesh, KJ Karczewski, MJ Daly, ...
Nature genetics 54 (10), 1466-1469, 2022
Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment
WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ...
BioRxiv, 2020.08. 25.267336, 2020
CRISPR/Cas9 Genome Engineering in Engraftable Human Brain-Derived Neural Stem Cells
DP Dever, SG Scharenberg, J Camarena, EJ Kildebeck, JT Clark, ...
iScience 15, 524-535, 2019
Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics
KA Jagadeesh, KK Dey, DT Montoro, R Mohan, S Gazal, JM Engreitz, ...
bioRxiv, 2021.03. 19.436212, 2021
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