| ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ... Stem cell reports 6 (3), 342-356, 2016 | 301 | 2016 |
| Physiological characterisation of human iPS-derived dopaminergic neurons EM Hartfield, M Yamasaki-Mann, HJ Ribeiro Fernandes, J Vowles, ... PloS one 9 (2), e87388, 2014 | 160 | 2014 |
| Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons F Zambon, M Cherubini, HJR Fernandes, C Lang, BJ Ryan, V Volpato, ... Human Molecular Genetics 28 (12), 2001-2013, 2019 | 111 | 2019 |
| Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing FH Siddiqi, FM Menzies, A Lopez, E Stamatakou, C Karabiyik, R Ureshino, ... Nature communications 10 (1), 1817, 2019 | 86 | 2019 |
| Delineating nonmotor symptoms in early Parkinson's disease and first‐degree relatives F Baig, M Lawton, M Rolinski, C Ruffmann, K Nithi, SG Evetts, ... Movement Disorders 30 (13), 1759-1766, 2015 | 70 | 2015 |
| Single-cell transcriptomics of Parkinson’s disease human in vitro models reveals dopamine neuron-specific stress responses HJR Fernandes, N Patikas, S Foskolou, SF Field, JE Park, ML Byrne, ... Cell Reports 33 (2), 108263, 2020 | 59 | 2020 |
| Cellular reprogramming: a new approach to modelling Parkinson's disease EM Hartfield, HJR Fernandes, J Vowles, SA Cowley, R Wade-Martins Biochemical Society transactions 40 (5), 1152-1157, 2012 | 26 | 2012 |
| Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease P Vazquez-Arango, J Vowles, C Browne, E Hartfield, HJR Fernandes, ... Nucleic acids research 44 (22), 10960-10973, 2016 | 24 | 2016 |
| MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development GE Parada, R Munita, I Georgakopoulos-Soares, HJR Fernandes, ... Genome biology 22, 1-26, 2021 | 12 | 2021 |
| Development and application of high-throughput single cell lipid profiling: a study of SNCA-A53T human dopamine neurons SG Snowden, HJR Fernandes, J Kent, S Foskolou, P Tate, SF Field, ... Iscience 23 (11), 101703, 2020 | 10 | 2020 |
| Beyond the lysosome: Cholesterol role on endoplasmic reticulum and lipid droplets in Parkinson's disease HJR Fernandes Movement Disorders 33 (2), 342-342, 2018 | 3 | 2018 |
| Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models HJR Fernandes, BJ Ryan, R Wade-Martins Frontiers in Neuroscience 10, 578, 2016 | 3 | 2016 |
| A novel post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson’s disease GBA-N370S dopamine neurons H Bogetofte, BJ Ryan, P Jensen, DLE Vergoossen, MB Barnkob, L Kiani, ... bioRxiv, 2021.06. 30.450333, 2021 | 1 | 2021 |
| Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson’s disease GBA-N370S dopamine neurons H Bogetofte, BJ Ryan, P Jensen, SI Schmidt, DLE Vergoossen, ... Cell Reports 42 (3), 2023 | | 2023 |
| CRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neuronal cell death S Pavlou, S Foskolou, N Patikas, SF Field, EK Papachristou, CD Santos, ... Scientific Reports 13 (1), 3934, 2023 | | 2023 |
| Mitochondrial and Endoplasmic Reticulum Stress Trigger Triglyceride Accumulation in Models of Parkinson’s Disease Independent of Mutations in MAPT HJR Fernandes, JP Kent, M Bruntraeger, AR Bassett, A Koulman, ... Metabolites 13 (1), 112, 2023 | | 2023 |
| Surface charge and dynamic mechanoelectrical stimuli improves adhesion, proliferation and differentiation of neuron-like cells T Marques-Almeida, HJR Fernandes, S Lanceros-Mendez, C Ribeiro Journal of Materials Chemistry B 11 (1), 144-153, 2023 | | 2023 |
| IMPACT & TREATMENT OF NON-MOTOR SYMPTOMS IN EARLY PARKINSON'S DISEASE F Baig, M Lawton, M Rolinski, C Ruffmann, K Nithi, S Evetts, H Fernandes, ... Journal of Neurology, Neurosurgery & Psychiatry 86 (11), e4-e4, 2015 | | 2015 |
| Dual proteostasis effect of glucocerebrosidase in the pathology of Parkinson's disease using patient derived induced pluripotent stem cells HJ Fernandes, E Hartfield, J Badger, J Vowles, S Evetts, K Talbot, M Hu, ... Society for Neuroscience, 43rd Annual Meeting, Nanosymposia Presentation 43, 2013 | | 2013 |
| Elucidating the role of GBA in the pathology of Parkinson's disease using human induced pluripotent stem cells derived from patients HJ Fernandes, E Hartfield, J Vowles, S Evetts, K Talbot, M Hu, S Cowley, ... Society for Neuroscience, 41st Annual Meeting, Nanosymposia Presentation 41, 2011 | | 2011 |
