| CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells R Flynn, A Grundmann, P Renz, W Hänseler, WS James, SA Cowley, ... Experimental hematology 43 (10), 838-848. e3, 2015 | 146 | 2015 |
| LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages A Härtlova, S Herbst, J Peltier, A Rodgers, O Bilkei‐Gorzo, A Fearns, ... The EMBO journal 37 (12), e98694, 2018 | 140 | 2018 |
| Correction of the ΔF508 mutation in the cystic fibrosis transmembrane conductance regulator gene by zinc-finger nuclease homology-directed repair CM Lee, R Flynn, JA Hollywood, MF Scallan, PT Harrison BioResearch open access 1 (3), 99-108, 2012 | 128 | 2012 |
| Alpha-synuclein induces the unfolded protein response in Parkinson’s disease SNCA triplication iPSC-derived neurons SM Heman-Ackah, R Manzano, JJM Hoozemans, W Scheper, R Flynn, ... Human molecular genetics 26 (22), 4441-4450, 2017 | 123 | 2017 |
| LRRK2 is recruited to phagosomes and co-recruits RAB8 and RAB10 in human pluripotent stem cell-derived macrophages H Lee, R Flynn, I Sharma, E Haberman, PJ Carling, FJ Nicholls, ... Stem Cell Reports 14 (5), 940-955, 2020 | 57 | 2020 |
| The current state of naïve human pluripotency BT Dodsworth, R Flynn, SA Cowley Stem Cells 33 (11), 3181-3186, 2015 | 39 | 2015 |
| Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by … NA Ababneh, J Scaber, R Flynn, A Douglas, P Barbagallo, A Candalija, ... Human molecular genetics 29 (13), 2200-2217, 2020 | 36 | 2020 |
| Expression of apolipoprotein AI in rabbit carotid endothelium protects against atherosclerosis R Flynn, K Qian, C Tang, N Dronadula, JM Buckler, B Jiang, S Wen, ... Molecular Therapy 19 (10), 1833-1841, 2011 | 33 | 2011 |
| Helper-dependent adenoviral vectors are superior in vitro to first-generation vectors for endothelial cell-targeted gene therapy R Flynn, JM Buckler, C Tang, F Kim, DA Dichek Molecular Therapy 18 (12), 2121-2129, 2010 | 19 | 2010 |
| Construction of a novel expression cassette for increasing transgene expression in vivo in endothelial cells of large blood vessels N Dronadula, L Du, R Flynn, J Buckler, J Kho, Z Jiang, S Tanaka, ... Gene therapy 18 (5), 501-508, 2011 | 14 | 2011 |
| Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs BT Dodsworth, K Hatje, M Rostovskaya, R Flynn, CA Meyer, SA Cowley Scientific Reports 10 (1), 10542, 2020 | 11 | 2020 |
| Application of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons C Überbacher, J Obergasteiger, M Volta, S Venezia, S Müller, I Pesce, ... Stem cell research 41, 101656, 2019 | 10 | 2019 |
| Improved animal models for testing gene therapy for atherosclerosis L Du, J Zhang, GRY De Meyer, R Flynn, DA Dichek Human Gene Therapy Methods 25 (2), 106-114, 2014 | 6 | 2014 |
| Overexpression of endothelial nitric oxide synthase improves endothelium-dependent vasodilation in arteries infused with helper-dependent adenovirus B Jiang, L Du, R Flynn, N Dronadula, J Zhang, F Kim, D Dichek Human gene therapy 23 (11), 1166-1175, 2012 | 6 | 2012 |
| Development of PCR conditions in a silicon microreactor DNA-amplification device MH Hofmann, A Akkoyun, R Flynn, A Mathewson, H Berney, MM Sheehan International Journal of Environmental Analytical Chemistry 84 (11), 821-833, 2004 | 5 | 2004 |
| Application of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons C Uberbacher, J Obergasteiger, M Volta, S Venezia, S Muller, I Pesce, ... Stem Cell Research 41, 101656-101656, 2019 | 4 | 2019 |
| Rates of homology directed repair of CRISPR-Cas9 induced double strand breaks are lower in naïve compared to primed human pluripotent stem cells BT Dodsworth, K Hatje, CA Meyer, R Flynn, SA Cowley Stem Cell Research 46, 101852, 2020 | 2 | 2020 |
| Deformable image registration (DIR) and radiobiological recalculation for retreat plan evaluation L Stenzel, R Flynn, M Moore RADIOTHERAPY AND ONCOLOGY 152, S888-S888, 2020 | | 2020 |
| PO-1625: Deformable image registration (DIR) and radiobiological recalculation for retreat plan evaluation L Stenzel, R Flynn, M Moore Radiotherapy and Oncology 152, S888, 2020 | | 2020 |
| Correction> 80% of CF Causing Mutations in CF Cells Using ZFN Homology-Directed Repair JA Hollywood, CM Lee, K Kaschig, R Flynn, MF Scallan, PT Harrison IRISH JOURNAL OF MEDICAL SCIENCE 185, S36-S37, 2016 | | 2016 |
sally cowleyHead, James Martin Stem Cell Facility, University of OxfordBestätigte E-Mail-Adresse bei path.ox.ac.uk
