| BET bromodomain inhibition as a therapeutic strategy to target c-Myc JE Delmore, GC Issa, ME Lemieux, PB Rahl, J Shi, HM Jacobs, E Kastritis, ... Cell 146 (6), 904-917, 2011 | 3177 | 2011 |
| RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia J Zuber, J Shi, E Wang, AR Rappaport, H Herrmann, EA Sison, D Magoon, ... Nature 478 (7370), 524-528, 2011 | 2145 | 2011 |
| Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control I Barbieri, K Tzelepis, L Pandolfini, J Shi, G Millán-Zambrano, SC Robson, ... Nature 552 (7683), 126-131, 2017 | 956 | 2017 |
| The mechanisms behind the therapeutic activity of BET bromodomain inhibition J Shi, CR Vakoc Molecular cell 54 (5), 728-736, 2014 | 897 | 2014 |
| Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains J Shi, E Wang, JP Milazzo, Z Wang, JB Kinney, CR Vakoc Nature biotechnology 33 (6), 661-667, 2015 | 789 | 2015 |
| Roles of Arabidopsis WRKY18, WRKY40 and WRKY60 transcription factors in plant responses to abscisic acid and abiotic stress H Chen, Z Lai, J Shi, Y Xiao, Z Chen, X Xu BMC plant biology 10, 1-15, 2010 | 571 | 2010 |
| Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation J Shi, WA Whyte, CJ Zepeda-Mendoza, JP Milazzo, C Shen, JS Roe, ... Genes & development 27 (24), 2648-2662, 2013 | 493 | 2013 |
| The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability B King, T Trimarchi, L Reavie, L Xu, J Mullenders, P Ntziachristos, ... Cell 153 (7), 1552-1566, 2013 | 350 | 2013 |
| POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer YH Huang, O Klingbeil, XY He, XS Wu, G Arun, B Lu, TDD Somerville, ... Genes & development 32 (13-14), 915-928, 2018 | 346 | 2018 |
| Optimized base editors enable efficient editing in cells, organoids and mice MP Zafra, EM Schatoff, A Katti, M Foronda, M Breinig, AY Schweitzer, ... Nature biotechnology 36 (9), 888-893, 2018 | 337 | 2018 |
| An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance J Zuber, AR Rappaport, W Luo, E Wang, C Chen, AV Vaseva, J Shi, ... Genes & development 25 (15), 1628-1640, 2011 | 305 | 2011 |
| Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem-and progenitor cells in acute myeloid leukemia (AML) H Herrmann, K Blatt, J Shi, KV Gleixner, S Cerny-Reiterer, L Müllauer, ... Oncotarget 3 (12), 1588, 2012 | 180 | 2012 |
| BET bromodomain inhibition releases the mediator complex from select cis-regulatory elements AS Bhagwat, JS Roe, BYL Mok, AF Hohmann, J Shi, CR Vakoc Cell reports 15 (3), 519-530, 2016 | 176 | 2016 |
| Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition AF Hohmann, LJ Martin, JL Minder, JS Roe, J Shi, S Steurer, G Bader, ... Nature chemical biology 12 (9), 672-679, 2016 | 175 | 2016 |
| Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma GL Brien, D Remillard, J Shi, ML Hemming, J Chabon, K Wynne, ... Elife 7, e41305, 2018 | 165 | 2018 |
| NSD3-short is an adaptor protein that couples BRD4 to the CHD8 chromatin remodeler C Shen, JJ Ipsaro, J Shi, JP Milazzo, E Wang, JS Roe, Y Suzuki, ... Molecular cell 60 (6), 847-859, 2015 | 161 | 2015 |
| Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia CC Bell, KA Fennell, YC Chan, F Rambow, MM Yeung, D Vassiliadis, ... Nature communications 10 (1), 2723, 2019 | 156 | 2019 |
| Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia E Wang, S Kawaoka, M Yu, J Shi, T Ni, W Yang, J Zhu, RG Roeder, ... Proceedings of the National Academy of Sciences 110 (10), 3901-3906, 2013 | 155 | 2013 |
| Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells JD Grevet, X Lan, N Hamagami, CR Edwards, L Sankaranarayanan, X Ji, ... Science 361 (6399), 285-290, 2018 | 151 | 2018 |
| In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer Z Chen, E Arai, O Khan, Z Zhang, SF Ngiow, Y He, H Huang, S Manne, ... Cell 184 (5), 1262-1280. e22, 2021 | 144 | 2021 |
