| Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma JL Kopp, G von Figura, E Mayes, FF Liu, CL Dubois, JP Morris, FC Pan, ... Cancer cell 22 (6), 737-750, 2012 | 741 | 2012 |
| SOX9 is required for maintenance of the pancreatic progenitor cell pool PA Seymour, KK Freude, MN Tran, EE Mayes, J Jensen, R Kist, G Scherer, ... Proceedings of the National Academy of Sciences 104 (6), 1865-1870, 2007 | 695 | 2007 |
| Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas M Sander, L Sussel, J Conners, D Scheel, J Kalamaras, F Dela Cruz, ... Development 127 (24), 5533-5540, 2000 | 684 | 2000 |
| Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. M Sander, A Neubüser, J Kalamaras, HC Ee, GR Martin, MS German Genes & development 11 (13), 1662-1673, 1997 | 682 | 1997 |
| Inactivation of specific β cell transcription factors in type 2 diabetes S Guo, C Dai, M Guo, B Taylor, JS Harmon, M Sander, RP Robertson, ... The Journal of clinical investigation 123 (8), 3305-3316, 2013 | 535 | 2013 |
| Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas JL Kopp, CL Dubois, AE Schaffer, E Hao, HP Shih, PA Seymour, J Ma, ... Development 138 (4), 653-665, 2011 | 534 | 2011 |
| Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ... Cell metabolism 16 (4), 435-448, 2012 | 484 | 2012 |
| Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer J Font-Burgada, S Shalapour, S Ramaswamy, B Hsueh, D Rossell, ... Cell 162 (4), 766-779, 2015 | 466 | 2015 |
| The β cell transcription factors and development of the pancreas M Sander, MS German Journal of molecular medicine 75, 327-340, 1997 | 456 | 1997 |
| Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling J Cai, Y Qi, X Hu, M Tan, Z Liu, J Zhang, Q Li, M Sander, M Qiu Neuron 45 (1), 41-53, 2005 | 433 | 2005 |
| Pancreas organogenesis: from lineage determination to morphogenesis HP Shih, A Wang, M Sander Annual review of cell and developmental biology 29, 81-105, 2013 | 383 | 2013 |
| Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells BL Taylor, FF Liu, M Sander Cell reports 4 (6), 1262-1275, 2013 | 367 | 2013 |
| The MafA transcription factor appears to be responsible for tissue-specific expression of insulin T Matsuoka, I Artner, E Henderson, A Means, M Sander, R Stein Proceedings of the National Academy of Sciences 101 (9), 2930-2933, 2004 | 364 | 2004 |
| Ventral neural patterning by Nkx homeobox genes: Nkx6. 1 controls somatic motor neuron and ventral interneuron fates M Sander, S Paydar, J Ericson, J Briscoe, E Berber, M German, ... Genes & development 14 (17), 2134-2139, 2000 | 344 | 2000 |
| Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors AE Schaffer, KK Freude, SB Nelson, M Sander Developmental cell 18 (6), 1022-1029, 2010 | 336 | 2010 |
| Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification A Vallstedt, J Muhr, A Pattyn, A Pierani, M Mendelsohn, M Sander, ... Neuron 31 (5), 743-755, 2001 | 323 | 2001 |
| Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ... Nature genetics 54 (5), 560-572, 2022 | 292 | 2022 |
| Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells R Carpentier, RE Suñer, N Van Hul, JL Kopp, JB Beaudry, S Cordi, ... Gastroenterology 141 (4), 1432-1438. e4, 2011 | 292 | 2011 |
| Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity AE Schaffer, BL Taylor, JR Benthuysen, J Liu, F Thorel, W Yuan, Y Jiao, ... PLoS genetics 9 (1), e1003274, 2013 | 282 | 2013 |
| Sox9 plays multiple roles in the lung epithelium during branching morphogenesis BE Rockich, SM Hrycaj, HP Shih, MS Nagy, MAH Ferguson, JL Kopp, ... Proceedings of the National Academy of Sciences 110 (47), E4456-E4464, 2013 | 274 | 2013 |
